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14.384 Articles in journals published by the UPC
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  • Biomecánica: Órgano de la Sociedad Ibérica de Biomecánica y Biomateriales
  • 2001, vol. 9, núm. 1. Desembre
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Potential periodontal regeneration by application of monoclonal antibodies against integrin-subunits a6 and b1

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10.5821/sibb.v9i1.1662
 
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hdl:2099/5596

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Georg Graber, Hans
Becker, Christoph
Lampert, Friedrich
Document typeArticle
Defense date2001-12
PublisherSociedad Ibérica de Biomecánica y Biomateriales
Rights accessOpen Access
Attribution-NonCommercial-NoDerivs 2.5 Spain
This work is protected by the corresponding intellectual and industrial property rights. Except where otherwise noted, its contents are licensed under a Creative Commons license : Attribution-NonCommercial-NoDerivs 2.5 Spain
Abstract
Successful guided tissue regeneration (GTR) should result in a functional attachment apparatus of the periodontium. The crucial points in the healing process are potential microbiological colonization of mechanical barrier membranes, lacking contact to the connective tissue and apical growth of the gingival epithelium. The membranes‘ success might be improved by equipping them with antibiotics, specific inhibitors for the epithelial growth and growth factors for periodontal ligament cells (PLC) or progenitor cells. Monoclonal antibodies (mAb) directed to integrin subunits a6 and b1 were tested for their specificity to epithelial growth. In vitro assays were performed as direct and indirect contact by seeding the human HaCaT-cell-line and gingival fibroblasts.
CitationGeorg Graber, Hans. [et al]. Potential periodontal regeneration by application of monoclonal antibodies against integrin-subunits a6 and b1. Biomecánica, 2001, vol. XI, núm. 1, p. 49-54. 
URIhttp://hdl.handle.net/2099/5596
DOI10.5821/sibb.v9i1.1662
ISSN1885-9518
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  • Biomecánica: Órgano de la Sociedad Ibérica de Biomecánica y Biomateriales - 2001, vol. 9, núm. 1. Desembre [11]
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