Browsing by Subject "G proteins -- Receptors"
Now showing items 1-8 of 8
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Beyond spectral tuning: human cone visual pigments adopt different transient conformations for chromophore regeneration
(2016-03)
Article
Open AccessHuman red and green visual pigments are seven transmembrane receptors of cone photoreceptor cells of the retina that mediate color vision. These pigments share a very high degree of homology and have been assumed to feature ... -
Effect of sodium valproate on the conformational stability of the visual G Protein-coupled receptor rhodopsin
(2021-05-19)
Article
Open AccessRhodopsin is the G protein-coupled receptor of rod photoreceptor cells that mediates vertebrate vision at low light intensities. Mutations in rhodopsin cause inherited retinal degenerative diseases such as retinitis ... -
Elaboración de un modelo 3D del receptor Humano de NK1 a partir del receptor delta Opiode
(Universitat Politècnica de Catalunya, 2015-06)
Master thesis
Open AccessLa publicación de la primera estructura cristalográfica de resolución atómica de un miembro de la familia de los receptores acoplados a proteínas G (GPCR) como es la Rodopsina Bovina (Rho) (1)marcó el comienzo de los ... -
Human blue cone opsin regeneration involves secondary retinal binding with analog specificity
(2018-03-27)
Article
Open AccessHuman color vision is mediated by the red, green, and blue cone visual pigments. Cone opsins are G-protein-coupled receptors consisting of an opsin apoprotein covalently linked to the 11-cis-retinal chromophore. All visual ... -
Hydrophobic amino acids at the cytoplasmic ends of helices 3 and 6 of rhodopsin conjointly modulate transducin activation
(2011-02-15)
Article
Restricted access - publisher's policyRhodopsin is the visual photoreceptor responsible for dim light vision. This receptor is located in the rod cell of the retina and is a prototypical member of the G-protein-coupled receptor superfamily. The structural ... -
Ligand binding mechanisms in human cone visual pigments
(2019-07)
Article
Open AccessVertebrate vision starts with light absorption by visual pigments in rod and cone photoreceptor cells of the retina. Rhodopsin, in rod cells, responds to dim light, whereas three types of cone opsins (red, green, and blue) ... -
Mercury-induced dark-state instability and photobleaching alterations of the visual G-protein coupled receptor rhodopsin
(2014-07-01)
Article
Restricted access - publisher's policyMercuric compounds were previously shown to affect the visual phototransduction cascade, and this could result in vision impairment. We have analyzed the effect of mercuric chloride on the structure and stability of the ... -
Obtención de receptores muscarínicos de acetilcolina recombinantes involucrados en patologías neurodegenerativas
(Universitat Politècnica de Catalunya, 2014-02)
Master thesis
Open AccessRecientemente se han logrado grandes avances en la determinación de la estructura y función de los receptores acoplados a proteínas G (GPCR’s). Los GPCR´s constituyen gran familia de proteína integrales de membrana y se ...
