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An invasive and a noninvasive approach for the automatic differentiation of obstructive and central hypopneas
dc.contributor.author | Morgenstern de Muller, Christian Rudolf |
dc.contributor.author | Schwaibold, Matthias |
dc.contributor.author | Randerath, Winfried J. |
dc.contributor.author | Bolz, Armin |
dc.contributor.author | Jané Campos, Raimon |
dc.contributor.other | Universitat Politècnica de Catalunya. Departament d'Enginyeria de Sistemes, Automàtica i Informàtica Industrial |
dc.contributor.other | Institut de Bioenginyeria de Catalunya |
dc.date.accessioned | 2010-11-05T09:53:57Z |
dc.date.available | 2010-11-05T09:53:57Z |
dc.date.created | 2010-04-15 |
dc.date.issued | 2010-04-15 |
dc.identifier.citation | Morgenstern, C.R. [et al.]. An invasive and a noninvasive approach for the automatic differentiation of obstructive and central hypopneas. "IEEE transactions on biomedical engineering", 15 Abril 2010, vol. 57, núm. 8, p. 1927-1936. |
dc.identifier.issn | 0018-9294 |
dc.identifier.uri | http://hdl.handle.net/2117/10135 |
dc.description.abstract | The automatic differentiation of obstructive and central respiratory events is a major challenge in the diagnosis of sleep-disordered breathing. Esophageal pressure (Pes) measurement is the gold-standard method to identify these events. This study presents a new classifier that automatically differentiates obstructive and central hypopneas with the Pes signal and a new approach for an automatic noninvasive classifierwith nasal airflow. An overall of 28 patients underwent night polysomnography with Pes recording, and a total of 769 hypopneas were manually scored by human experts to create a gold-standard annotation set. Features were automatically extracted fromthe Pes signal to train and test the classifiers (discriminant analysis, support vector machines, and adaboost). After a significantly (p < 0.01) higher incidence of inspiratory flow limitation episodes in obstructive hypopneas was objectively, invasively assessed compared to central hypopneas, the feasibility of an automatic noninvasive classifier with features extracted from the airflow signal was demonstrated. The automatic invasive classifier achieved a mean sensitivity, specificity, and accuracy of 0.90 after a 100-fold cross validation. The automatic noninvasive feasibility study obtained similar hypopnea differentiation results as a manual noninvasive classification algorithm. Hence, both systems seem promising for the automatic differentiation of obstructive and central hypopneas. |
dc.format.extent | 10 p. |
dc.language.iso | eng |
dc.subject | Àrees temàtiques de la UPC::Informàtica::Aplicacions de la informàtica::Bioinformàtica |
dc.subject | Àrees temàtiques de la UPC::Ciències de la salut |
dc.subject.lcsh | Esophageal Diseases |
dc.subject.lcsh | Biomedical engineering |
dc.subject.lcsh | Polysomnography |
dc.title | An invasive and a noninvasive approach for the automatic differentiation of obstructive and central hypopneas |
dc.type | Article |
dc.subject.lemac | Enginyeria biomèdica |
dc.subject.lemac | Respiració -- Mesurament |
dc.subject.lemac | Síndromes d'apnea del son |
dc.contributor.group | Universitat Politècnica de Catalunya. SISBIO - Senyals i Sistemes Biomèdics |
dc.identifier.doi | 10.1109/TBME.2010.2047505 |
dc.description.peerreviewed | Peer Reviewed |
dc.relation.publisherversion | http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=5447740&tag=1 |
dc.rights.access | Open Access |
local.identifier.drac | 2748824 |
dc.description.version | Postprint (published version) |
local.citation.author | Morgenstern, C.R.; Schwaibold, M.; Randerath, W.; Bolz, A.; Jané, R. |
local.citation.publicationName | IEEE transactions on biomedical engineering |
local.citation.volume | 57 |
local.citation.number | 8 |
local.citation.startingPage | 1927 |
local.citation.endingPage | 1936 |
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