In this paper we use a simplified model of cardiac excitation-contraction coupling to study the effect of tissue deformation on the dynamics of alternans, i.e., alternations in the duration of the cardiac action potential, ...

Hutchinson–Gilford progeria syndrome (HGPS) is a rare genetic disease caused by defective prelamin A processing, leading to nuclear lamina alterations, severe cardiovascular pathology, and premature death. Prelamin A ...

Cardiac ryanodine receptor (RyR2) gain-of-function mutations cause catecholaminergic polymorphic ventricular tachycardia, a condition characterized by prominent ventricular ectopy in response to catecholamine stress, which ...

Percutaneous auricular vagus nerve stimulation (aVNS) is a promising therapy to treat a wide range of diseases by stimulating the auricular branch of the vagus nerve along a well-defined neuroanatomical pathway. It induces ...

We introduce Cardinality Networks, a new CNF encoding of cardinality constraints. It improves upon the previously existing encodings such as the sorting networks of [ES06] in that it requires much less clauses and auxiliary ...

As the limits of human exploration expand farther into space, there becomes an increasing need to condition and maintain the human body for life beyond our planet. Astronauts on space missions experience various detrimental ...