Paternal contribution to development: Spermgenetic damage and repair in fish
Visualitza/Obre
10.1016/j.aquaculture.2016.03.007
Inclou dades d'ús des de 2022
Cita com:
hdl:2117/99567
Tipus de documentArticle
Data publicació2016
Condicions d'accésAccés obert
Llevat que s'hi indiqui el contrari, els
continguts d'aquesta obra estan subjectes a la llicència de Creative Commons
:
Reconeixement-NoComercial-SenseObraDerivada 3.0 Espanya
Abstract
In this review we provide an overview of the components of the spermatozoa playing an important role in reproductive success beyond fertilization , showing the relationship between the integrity of the diverse elements and the development of a healthy offspring . The present knowledge about fish sperm chromatin organization, epigenetic modifications of DNA and histones and sperm - borne RNAs , essential i n controlling embryo development, is summarized , pointing out the possibility of using specific genes or transcripts as biomarkers of sperm quality . Data about commercial species are reported when available and more detailed information about zebrafish sperm is presented. Considering the implications that the integrity of sperm genom e and epigenom e has on the preservation of a proper genotype and phenotype in the progeny, the methods applied for the study of chromatin damage and for the study of transcr iptome are described. Moreover we discuss some injuring agents affecting paternal information , from the presence of contaminants in the aquatic environment, to the reproductive *Manuscript Click here to download Manuscript: Herrez et al revised aquaculture.docx Click here to view linked References practices applied in fish farming . The consequences of fertilizing with damaged spermatozoa, as well as the zygotic ability to repair damage are also reviewed.
CitacióHerráez, M.P., Ausió, J., Devaux, A., González-Rojo, S., Fernández-Díez, C., Bony, S., Saperas, N., Robles, V. Paternal contribution to development: Spermgenetic damage and repair in fish. "Journal of the World Aquaculture Society", 2016.
ISSN0893-8849
Fitxers | Descripció | Mida | Format | Visualitza |
---|---|---|---|---|
AQUA-D-15-00909R2.pdf | 996,8Kb | Visualitza/Obre |