Longitudinal and transversal bioimpedance measurements in addition to diagnosis of heart failure
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Heart Failure (HF) is a clinical syndrome characterised by signs of systemic and pulmonary fluid retention, shortness of breath and/or fatigue. There is a lack of reliable indicators of disease state. Benefits and applicability of non-invasive bioimpedance measurement in the hydration state of soft tissues have been validated, fundamentally, in dialysis patients. Four impedance configurations (2 longitudinal and 2 transversal) were analyzed in 48 HF patients (M=28, F=20) classified according to a clinical disease severity score (CDSS) derived from the Framingham criteria: CDSS2 (G1: M= 23, F= 14) and CDSS>2 (G2: M= 5, F= 6). The aim of this study is to analyze longitudinal and transversal bioimpedance measurement at 50 kHz, in addition to clinical diagnosis parameters of heart failure, including: clinical disease severity score (CDSS) and a biomarker concentrations (NTproBNP). The Kolmogorov-Smirnov test was used for the normality test of all variables. The CDSS, NTproBNP and impedance parameters between groups (G1 and G2) were compared by mean of Mann Withney U-test. The statistical significance was considered with P < 0.05. Whole-body impedance measured was analyzed using RXc graph.
CitationRibas, N. [et al.]. Longitudinal and transversal bioimpedance measurements in addition to diagnosis of heart failure. A: International Conference on Electrical Bioimpedance. "Journal of Physics: Conference Series. Volume 224, 2010". Gainesville-Florid, April 04-08: 2010.