Nanostructured amphiphilic systems based on hyaluronic acid ionic complexes

Abstract

In this communication we wish to report on HyA ionic complexes prepared by coupling with a) choline-based surfactants (nACh·HyA complexes), and b) alkylphosphonium surfactants (nATMP·HyA complexes) with n being the number of carbons of the alkanoyl or alkyl side chain. nACh surfactants are synthesized from choline and fatty acids, and distinguished because they are fully biobased and biocompatible. The nATMP surfactants have been scarcely studied as counterions of polyacids in spite of being more stable to heat and less harmful than their alkylammonium analogs.