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Chemotherapeutic drug-specific alteration of microvascular blood flow in murine breast cancer as measured by diffuse correlation spectroscopy
dc.contributor.author | Gabriel, Ramirez |
dc.contributor.author | Proctor, Ashley R. |
dc.contributor.author | Jung, Ki Won |
dc.contributor.author | Wu, Tong Tong |
dc.contributor.author | Han, Songfeng |
dc.contributor.author | Adams, Russell R. |
dc.contributor.author | Ren, Jingxuan |
dc.contributor.author | Byun, Daniel K. |
dc.contributor.author | Madden, Kelley S. |
dc.contributor.author | Brown, Edward B. |
dc.contributor.author | Foster, Thomas H. |
dc.contributor.author | Farzam, Parisa |
dc.contributor.author | Durduran, Turgut |
dc.contributor.author | Choe, Regine |
dc.contributor.other | Universitat Politècnica de Catalunya. Institut de Ciències Fotòniques |
dc.date.accessioned | 2016-10-18T10:23:04Z |
dc.date.available | 2016-10-18T10:23:04Z |
dc.date.issued | 2016-09-01 |
dc.identifier.citation | Gabriel, Ramirez [et al.]. Chemotherapeutic drug-specific alteration of microvascular blood flow in murine breast cancer as measured by diffuse correlation spectroscopy. "Biomedical Optics Express", 1 Setembre 2016, vol. 7, núm. 9, p. 3610-3630. |
dc.identifier.issn | 2156-7085 |
dc.identifier.uri | http://hdl.handle.net/2117/90835 |
dc.description.abstract | The non-invasive, in vivo measurement of microvascular blood flow has the potential to enhance breast cancer therapy monitoring. Here, longitudinal blood flow of 4T1 murine breast cancer (N=125) under chemotherapy was quantified with diffuse correlation spectroscopy based on layer models. Six different treatment regimens involving doxorubicin, cyclophosphamide, and paclitaxel at clinically relevant doses were investigated. Treatments with cyclophosphamide increased blood flow as early as 3 days after administration, whereas paclitaxel induced a transient blood flow decrease at 1 day after administration. Early blood flow changes correlated strongly with the treatme |
dc.format.extent | 20 p. |
dc.language.iso | eng |
dc.publisher | OSA |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Spain |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ |
dc.subject | Àrees temàtiques de la UPC::Física |
dc.subject.lcsh | spectroscopy |
dc.subject.other | Medical optics and biotechnology |
dc.title | Chemotherapeutic drug-specific alteration of microvascular blood flow in murine breast cancer as measured by diffuse correlation spectroscopy |
dc.type | Article |
dc.subject.lemac | Òptica |
dc.description.peerreviewed | Peer Reviewed |
dc.relation.publisherversion | https://www.osapublishing.org/boe/abstract.cfm?uri=boe-7-9-3610 |
dc.rights.access | Open Access |
dc.description.version | Postprint (published version) |
local.citation.publicationName | Biomedical Optics Express |
local.citation.volume | 7 |
local.citation.number | 9 |
local.citation.startingPage | 3610 |
local.citation.endingPage | 3630 |
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