Roadmap on biosensing and photonics with advanced nano-optical methods
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Tipus de documentArticle
Data publicació2016-05-10
EditorIOP
Condicions d'accésAccés obert
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Reconeixement-NoComercial-SenseObraDerivada 3.0 Espanya
Abstract
This roadmap, through the contributions of ten groups worldwide, contains different techniques,
methods and materials devoted to sensing in nanomedicine. Optics is used in different ways in
the detection schemes. Raman, fluorescence and infrared spectroscopies, plasmonics, second
harmonic generation and optical tweezers are all used in applications from single molecule
detection (both in highly diluted and in highly concentrated solutions) to single cell
manipulation. In general, each optical scheme, through device miniaturization and
electromagnetic field localization, exploits an intrinsic optical enhancement mechanism in order
to increase the sensitivity and selectivity of the device with respect to the complex molecular
construct. The materials used for detection include nanoparticles and nanostructures fabricated
with different 2D and 3D lithographic methods. It is shown that sensitivity to a single molecule is
already accessible whether the system under study is a single cell or a multitude of cells in a
molecular mixture. Throughout the roadm
CitacióFabrizio, Enzo Di [et al.]. Roadmap on biosensing and photonics with advanced nano-optical methods. "Journal of Optics", 10 Maig 2016, vol. 18, núm. 063003, p. 1-27.
GuardóDocument premiat
ISSN2040-8978
Versió de l'editorhttp://iopscience.iop.org/article/10.1088/2040-8978/18/6/063003
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