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dc.contributor.authorValle Mendoza, Luis Javier del
dc.contributor.authorFranco García, María Lourdes
dc.contributor.authorKatsarava, Ramaz
dc.contributor.authorPuiggalí Bellalta, Jordi
dc.contributor.otherUniversitat Politècnica de Catalunya. Departament d'Enginyeria Química
dc.date.accessioned2016-09-26T09:37:19Z
dc.date.available2016-09-26T09:37:19Z
dc.date.issued2016-01-01
dc.identifier.citationdel Valle, LJ., Franco, M., Katsarava, R., Puiggali, J. Electrospun biodegradable polymers loaded with bactericide agents. "AIMS MOLECULAR SCIENCE", 1 Gener 2016, vol. 3, núm. 1, p. 52-87.
dc.identifier.issn2372-0301
dc.identifier.urihttp://hdl.handle.net/2117/90182
dc.description.abstractDevelopment of materials with an antimicrobial activity is fundamental for different sectors, including medicine and health care, water and air treatment, and food packaging. Electrospinning is a versatile and economic technique that allows the incorporation of different natural, industrial, and clinical agents into a wide variety of polymers and blends in the form of micro/nanofibers. Furthermore, the technique is versatile since different constructs (e.g. those derived from single electrospinning, co-electrospinning, coaxial electrospinning, and miniemulsion electrospinning) can be obtained to influence the ability to load agents with different characteristics and stability and to modify the release behaviour. Furthermore, antimicrobial agents can be loaded during the electrospinning process or by a subsequent coating process. In order to the mitigate burst release effect, it is possible to encapsulate the selected drug into inorganic nanotubes and nanoparticles, as well as in organic cyclodextrine polysaccharides. In the same way, processes that involve covalent linkage of bactericide agents during surface treatment of electrospun samples may also be considered.; The present review is focused on more recent works concerning the electrospinning of antimicrobial polymers. These include chitosan and common biodegradable polymers with activity caused by the specific load of agents such as metal and metal oxide particles, quaternary ammonium compounds, hydantoin compounds, antibiotics, common organic bactericides, and bacteriophages.
dc.format.extent36 p.
dc.language.isoeng
dc.publisherAMER INST MATHEMATICAL SCIENCES-AIMS
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
dc.subjectÀrees temàtiques de la UPC::Enginyeria química
dc.subject.lcshPolymers
dc.subject.lcshBiomedical materials
dc.subject.lcshNanotechnology
dc.subject.lcshElectrospinning
dc.subject.otherElectrospinning
dc.subject.otherdrug encapsulation
dc.subject.othermetal particles
dc.subject.otherchitosan
dc.subject.otherhydantoin compounds
dc.subject.otherantibiotics
dc.subject.otherquaternary ammonium compounds
dc.subject.otherbactericides
dc.subject.otherbacteriophages
dc.subject.othertriclosan/cyclodextrin inclusion complexes
dc.subject.otherresistant staphylococcus-aureus
dc.subject.otherbiologically-active polymers
dc.subject.otherwound-dressing applications
dc.subject.otherantimicrobial activity
dc.subject.othersilver nanoparticles
dc.subject.otherquaternary ammonium
dc.titleElectrospun biodegradable polymers loaded with bactericide agents
dc.typeArticle
dc.subject.lemacPolímers
dc.subject.lemacBiomaterials
dc.subject.lemacNanotecnologia
dc.contributor.groupUniversitat Politècnica de Catalunya. PSEP - Polimers Sintètics: Estructura i Propietats. Polimers Biodegradables.
dc.identifier.doi10.3934/molsci.2016.1.52
dc.description.peerreviewedPeer Reviewed
dc.relation.publisherversionhttp://www.aimspress.com/article/10.3934/molsci.2016.1.52
dc.rights.accessOpen Access
drac.iddocument18545339
dc.description.versionPostprint (published version)
upcommons.citation.authordel Valle, LJ., Franco, M., Katsarava, R., Puiggali, J.
upcommons.citation.publishedtrue
upcommons.citation.publicationNameAIMS MOLECULAR SCIENCE
upcommons.citation.volume3
upcommons.citation.number1
upcommons.citation.startingPage52
upcommons.citation.endingPage87
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