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Influence of gap junction dynamics on the stability of reentrant waves in cadiac tissue
dc.contributor.author | Hawks, Claudia |
dc.contributor.author | Elorza Barbajero, Jorge |
dc.contributor.author | Echebarría Domínguez, Blas |
dc.contributor.author | Rodríguez Cantalapiedra, Inma |
dc.contributor.author | Peñaranda Ayllón, Angelina |
dc.contributor.author | Bragard, Jean |
dc.contributor.other | Universitat Politècnica de Catalunya. Departament de Física |
dc.date.accessioned | 2016-09-20T12:26:35Z |
dc.date.available | 2016-09-20T12:26:35Z |
dc.date.issued | 2015 |
dc.identifier.citation | Hawks, C., Elorza, J., Echebarria, B., Rodriguez Cantalapiedra, I., Peñaranda, A., Bragard, J. Influence of gap junction dynamics on the stability of reentrant waves in cadiac tissue. A: Computing in Cardiology Annual Conference. "Computing in Cardiology 42, 2015". Niza: 2015, p. 437-440. |
dc.identifier.isbn | 0276-6574 |
dc.identifier.uri | http://hdl.handle.net/2117/90072 |
dc.description.abstract | Constant conductances are often assumed when model- ing cardiac tissue. However experimental evidences have shown that gap junctions (GJ) actually connect adjacent cardiac myocytes. These GJ are complex proteins of the connexin family (Cx40; Cx43; Cx45 are the most common in human). These GJ modify the conductances between cardiac cell through a dynamical process. The aim of this study is to develop a bidomain model of the cardiac tis- sue where the dynamics of the connexins is also included. In particular we will compare the differences associated with the use of a monodomain versus bidomain formula- tion in inducing intra-cellular conductance variations. We have found that the monodomain formulation gives con- ductance variations a factor four to five larger with respect to the bidomain formulation |
dc.format.extent | 4 p. |
dc.language.iso | eng |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ |
dc.subject | Àrees temàtiques de la UPC::Ciències de la salut::Medicina::Anatomia i fisiologia humana |
dc.subject.lcsh | Gap junctions (Cell biology) |
dc.title | Influence of gap junction dynamics on the stability of reentrant waves in cadiac tissue |
dc.type | Conference report |
dc.subject.lemac | Unions gap (Biologia cel·lular) |
dc.contributor.group | Universitat Politècnica de Catalunya. BIOCOM-SC - Grup de Biologia Computacional i Sistemes Complexos |
dc.contributor.group | Universitat Politècnica de Catalunya. GICITED - Grup Interdiciplinari de Ciència i Tecnologia en l'Edificació |
dc.description.peerreviewed | Peer Reviewed |
dc.relation.publisherversion | http://www.cinc.org/archives/2015/pdf/0437.pdf |
dc.rights.access | Open Access |
local.identifier.drac | 18733991 |
dc.description.version | Postprint (published version) |
local.citation.author | Hawks, C.; Elorza, J.; Echebarria, B.; Rodriguez Cantalapiedra, I.; Peñaranda, A.; Bragard, J. |
local.citation.contributor | Computing in Cardiology Annual Conference |
local.citation.pubplace | Niza |
local.citation.publicationName | Computing in Cardiology 42, 2015 |
local.citation.startingPage | 437 |
local.citation.endingPage | 440 |