Assessment of responsiveness levels during sedation-analgesia by entropy analysis of EEG
Visualitza/Obre
Cita com:
hdl:2117/89087
Tipus de documentArticle
Data publicació2016-03-18
Condicions d'accésAccés obert
Tots els drets reservats. Aquesta obra està protegida pels drets de propietat intel·lectual i
industrial corresponents. Sense perjudici de les exempcions legals existents, queda prohibida la seva
reproducció, distribució, comunicació pública o transformació sense l'autorització del titular dels drets
Abstract
The level of sedation in patients undergoing medical procedures is decided to assure unconsciousness and prevent pain. The monitors of depth of anesthesia, based on the analysis of the electroencephalogram (EEG), have been progressively introduced into the daily practice to provide additional information about the state of the patient. However, the quantification of analgesia still remains an open problem. The purpose of this work was to analyze the capability of prediction of nociceptive responses based on refined multiscale entropy (RMSE) and auto mutual information function (AMIF) applied to EEG signals recorded in 378 patients scheduled to undergo ultrasonographic endoscopy under sedationanalgesia. Two observed categorical responses after the application of painful stimulation were analyzed: the evaluation of the Ramsay Sedation Scale (RSS) after nail bed compression and the presence of gag reflex (GAG) during endoscopy tube insertion. Also, BIS, heart rate (HR), predicted concentrations of propofol (CeProp) and remifentanil (CeRemi) were annotated with a resolution of 1 second. Results showed that functions based on RMSE, AMIF, HR and CeRemi permitted to predict different stimulation responses during sedation with better than BIS.
CitacióValencia, J., Melia, U., Vallverdu, M., Jospin, M., Jensen, E.W., Porta, A., Gambus, P., Caminal, P. Assessment of responsiveness levels during sedation-analgesia by entropy analysis of EEG. "Entropy: international and interdisciplinary journal of entropy and information studies", 18 Març 2016, vol. 18, núm. 3.
ISSN1099-4300
Fitxers | Descripció | Mida | Format | Visualitza |
---|---|---|---|---|
Article_UPCcommons.pdf | 296,7Kb | Visualitza/Obre |