The actual manufacturing process of lithium-ion batteries has a few potential areas to be improved. At iwb has been built a complete production line with the purpose of improving all the stages, including the filling and the following wetting of the cells. Because of the barely existence of a wetting measurement method in the literature, a method was already proposed in a former work. The system was composed of a vacuum chamber, a case to hold the cell’s layers that were pressed with a Plexiglas block, a liquid circuit, and a camera to record the phenomena. This master thesis has contributed to improve the method, redesigning the setup, and creating a completely new video analysis. A statistical model with four main factors has been formulated. These describe a pressure profile using as variables a filling and a wetting pressure, a held time, and the number of cycles this is repeated. The chosen response is the percentage that the electrolyte has soaked at the end on the process. The study is performed to provide guidance on the trends of the response. The maximal process’s performance with two cycles is one of the most relevant acquired results. Another worthy finding has been the great influence that the wetting pressure has on the soaked surface, in addition to the interaction that has this one with the filling pressure. The establishment of these patterns could serve as a guideline to develop improved battery production lines.