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dc.contributor.authorPeralvarez Marin, Alex
dc.contributor.authorGarriga Solé, Pere
dc.contributor.otherUniversitat Politècnica de Catalunya. Departament d'Enginyeria Química
dc.date.accessioned2016-03-16T14:53:06Z
dc.date.available2017-01-05T01:30:26Z
dc.date.issued2016-02-02
dc.identifier.citationPeralvarez, A., Garriga, P. Optogenetics comes of age: novel inhibitory light-gated anionic channels allow efficient silencing of neural function. "Chembiochem", 02 Febrer 2016, vol. 17, núm. 3, p. 204-206.
dc.identifier.issn1439-4227
dc.identifier.urihttp://hdl.handle.net/2117/84512
dc.descriptionThis is the peer reviewed version of the following article: A. Peralvárez-Marín, P. Garriga, Optogenetics Comes of Age: Novel Inhibitory Light-Gated Anionic Channels Allow Efficient Silencing of Neural Function. ChemBioChem 2016, 17, 204-206, which has been published in final form at http://dx.doi.org/10.1002/cbic.201500608. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving
dc.description.abstractOptogenetics, the developing field of research that uses light-switchable biochemical tools in a sophisticated technological approach to monitor or control neural function, is rapidly evolving with the discovery and development of novel microbial rhodopsins. Light-absorbing membrane proteins, as tools for brain research, are promoting new applications within the discipline of optogenetics. Light-gated rhodopsin ion channels with better intrinsic light sensitivity and improved resolution are needed to overcome some of the current limitations of existing molecules. The recent discovery of light-gated inhibitory anion channels opens new opportunities for studying physiological neural processes and, at the same time, represent a powerful approach for elucidating the mechanisms of neurological and mental disorders that could benefit from this approach.
dc.format.extent3 p.
dc.language.isoeng
dc.subjectÀrees temàtiques de la UPC::Enginyeria química::Química orgànica::Bioquímica
dc.subject.lcshNeurobiology
dc.subject.lcshCellular signal transduction
dc.subject.otherBrain function
dc.subject.otherLight-activated ion channels
dc.subject.otherRhodopsins
dc.subject.otherSignal transduction
dc.titleOptogenetics comes of age: novel inhibitory light-gated anionic channels allow efficient silencing of neural function
dc.typeArticle
dc.subject.lemacNeurobiologia
dc.subject.lemacTransducció de senyal cel·lular
dc.contributor.groupUniversitat Politècnica de Catalunya. GBMI - Grup de Biotecnologia Molecular i Industrial
dc.identifier.doi10.1002/cbic.201500608
dc.description.peerreviewedPeer Reviewed
dc.rights.accessOpen Access
local.identifier.drac17659553
dc.description.versionPostprint (published version)
local.citation.authorPeralvarez, A.; Garriga, P.
local.citation.publicationNameChembiochem
local.citation.volume17
local.citation.number3
local.citation.startingPage204
local.citation.endingPage206


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