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Precision proteogenomics reveals pan-cancer impact of germline variants
(Elsevier, 2025)
Article
Open AccessWe investigate the impact of germline variants on cancer patients’ proteomes, encompassing 1,064 individuals across 10 cancer types. We introduced an approach, “precision peptidomics,” mapping 337,469 coding germline ... -
Heterologous mRNA/MVA delivering trimeric-RBD as effective vaccination regimen against SARS-CoV-2: COVARNA Consortium
(Taylor and Francis, 2024)
Article
Open AccessDespite the high efficiency of current SARS-CoV-2 mRNA vaccines in reducing COVID-19 morbidity and mortality, waning immunity and the emergence of resistant variants underscore the need for novel vaccination strategies. ... -
Empowering cancer research in Europe: the EUCAIM cancer imaging infrastructure
(Springer Nature, 2025)
Internal report
Open AccessArtificial intelligence (AI) is a powerful technology with the potential to disrupt cancer detection, diagnosis and treatment. However, the development of new AI algorithms requires access to large and complex real-world ... -
The Federated European Genome–Phenome Archive as a global network for sharing human genomics data
(Nature Research, 2025)
Article
Restricted access - publisher's policyIn this era of rapidly expanding human genomics in research and healthcare, efficient data reuse is essential to maximize benefits for society. In response, the Federated European Genome–Phenome Archive (FEGA) was launched ... -
Risk of cancer development associated with disease-modifying therapies for multiple sclerosis: study protocol for a systematic review and meta-analysis of randomised and non-randomised studies
(BioMed Central (BMC), 2024)
Article
Open AccessBackground The association between cancer and multiple sclerosis has long been investigated. Several studies and reviews have examined the risk of cancer among patients with multiple sclerosis treated with disease-modifying ... -
BioASQ Synergy: a dialogue between question-answering systems and biomedical experts for promoting COVID-19 research
(Oxford University Press, 2024-08)
Article
Open AccessAbstract Objective This article presents the novel BioASQ Synergy research process which aims to facilitate the interaction between biomedical experts and automated question-answering systems. Materials and Methods The ... -
Multi-omic and single-cell profiling of chromothriptic medulloblastoma reveals genomic and transcriptomic consequences of genome instability
(Nature Research, 2024)
Article
Open AccessChromothripsis is a frequent form of genome instability, whereby a presumably single catastrophic event generates extensive genomic rearrangements of one or multiple chromosome(s). However, little is known about the ... -
Synthesis of All-Peptide-Based Rotaxane from a Proline-Containing Cyclic Peptide
(American Chemical Society, 2024)
Article
Open AccessRotaxane cross-linkers enhance the toughness of the resulting rotaxane cross-linked polymers through a stress dispersion effect, which is attributed to the mobility of the interlocked structure. To date, the compositional ... -
Threats from the Candida parapsilosis complex: the surge of multidrug resistance and a hotbed for new emerging pathogens
(American Society for Microbiology, 2024-11-07)
Article
Open AccessCandida parapsilosis is a common agent of candidiasis that has gained increased attention in recent years, culminating with its recent consideration as a high-priority fungal pathogen by the World Health Organization. ... -
The ELIXIR Biodiversity Community: Understanding short- and long-term changes in biodiversity
(F1000 Research Ltd, 2024)
Article
Open AccessBiodiversity loss is now recognised as one of the major challenges for humankind to address over the next few decades. Unless major actions are taken, the sixth mass extinction will lead to catastrophic effects on the ... -
Profiling Bacteria in the Lungs of Patients with Severe Influenza Versus COVID-19 with or without Aspergillosis
(American Thoracic Society, 2024)
Article
Open AccessRationale: The influence of the lung bacterial microbiome, including potential pathogens, in patients with influenza-associated pulmonary aspergillosis (IAPA) or coronavirus disease (COVID-19)–associated pulmonary aspergillosis ... -
MONFIT: multi-omics factorization-based integration of time-series data sheds light on Parkinson’s disease
(Oxford University Press, 2024-10)
Article
Open AccessParkinson’s disease (PD) is a severe and complex multifactorial neurodegenerative disease with still elusive pathophysiology preventing the development of curative treatments. Molecular deep phenotyping by longitudinal ...
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