Recent Submissions

  • A framework to assess the quality and impact of bioinformatics training across ELIXIR 

    Gurwitz, Kim T.; Singh Gaur, Prakash; Bellis, Louisa J.; Larcombe, Lee; Alloza, Eva; Laszlo Balint, Balint; Botzki, Alexander; Dimec, Jure; Dominguez del Angel, Victoria; Fernandes, Pedro L.; Korpelainen, Eija; Krause, Roland; Kuzak, Mateusz; Le Pera, Loredana; Leskošek, Brane; Lindvall, Jessica M.; Marek, Diana; Martinez, Paula A.; Muyldermans, Tuur; Nygård, Ståle; Palagi, Patricia M.; Peterson, Hedi; Psomopoulos, Fotis; Spiwok, Vojtech; Gelder, Celia W. G. van; Via, Allegra; Vidak, Marko; Wibberg, Daniel; Morgan, Sarah L.; Rustici, Gabriella (Public Library of Science (PLOS), 2020-07)
    Article
    Open Access
    ELIXIR is a pan-European intergovernmental organisation for life science that aims to coordinate bioinformatics resources in a single infrastructure across Europe; bioinformatics training is central to its strategy, which ...
  • Genomic evidence for recurrent genetic admixture during the domestication of Mediterranean olive trees (Olea europaea L.) 

    Julca, Irene; Marcet-Houben, Marina; Cruz, Fernando; Gómez-Garrido, Jèssica; Gaut, Brandon S.; Díez, Concepción M.; Gut, Ivo G.; Alioto, Tyler S.; Vargas, Pablo; Gabaldon, Toni (Springer Nature, 2020)
    Article
    Open Access
    Background Olive tree (Olea europaea L. subsp. europaea, Oleaceae) has been the most emblematic perennial crop for Mediterranean countries since its domestication around 6000 years ago in the Levant. Two taxonomic varieties ...
  • Detection of SARS-CoV-2 in a cat owned by a COVID-19−affected patient in Spain 

    Segalés, Joaquim; Puig, Mariona; Rodon, Jordi; Avila-Nieto, Carlos; Carrillo, Jorge; Cantero, Guillermo; Terrón, Maria Teresa; Cruz, Sílvia; Parera, Mariona; Noguera-Julián, Marc; Izquierdo-Useros, Nuria; Guallar, Victor; Vidal, Enric; Valencia, Alfonso; Blanco, Ignacio; Blanco, Julià; Clotet, Bonaventura; Vergara-Alert, Júlia (National Academy of Sciences, 2020-10)
    Article
    Open Access
    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological agent of COVID-19, is considered a zoonotic pathogen mainly transmitted human to human. Few reports indicate that pets may be exposed to the ...
  • Pigs are not susceptible to SARS‐CoV‐2 infection but are a model for viral immunogenicity studies 

    Vergara-Alert, Júlia; Rodon, Jordi; Carrillo, Jorge; Te, Nigeer; Izquierdo‐Useros, Nuria; Rodríguez de la Concepción, María Luisa; Ávila‐Nieto, Carlos; Guallar, Victor; Valencia, Alfonso; Cantero, Guillermo; Blanco, Julià; Clotet, Bonaventura; Bensaid, Albert; Segalés, Joaquim (Wiley, 2020-10)
    Article
    Open Access
    Conventional piglets were inoculated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) through different routes, including intranasal, intratracheal, intramuscular and intravenous ones. Although piglets ...
  • Hybridization and the origin of new yeast lineages 

    Gabaldón, Toni (Oxford University Press (OUP), 2020-08)
    Article
    Open Access
    Hybrids originate from the mating of two diverged organisms, resulting in novel lineages that have chimeric genomes. Hybrids may exhibit unique phenotypic traits that are not necessarily intermediate between those present ...
  • Fungal evolution: cellular, genomic and metabolic complexity 

    Naranjo‐Ortiz, Miguel A.; Gabaldón, Toni (Wiley, 2020-10)
    Article
    Open Access
    The question of how phenotypic and genomic complexity are inter‐related and how they are shaped through evolution is a central question in biology that historically has been approached from the perspective of animals and ...
  • Predicción de mortalidad en recién nacidos prematuros. Revisión sistemática actualizada 

    Río, Ruth del; Thió, Marta; Bosio, Mattia; Figueras, Josep; Iriondo, Martín (Elsevier, 2020-07)
    Article
    Open Access
    Introducción La prematuridad extrema se asocia a altas tasas de mortalidad. Para profesionales y familias, es prioritario establecer de forma individualizada las probabilidades de muerte en diferentes momentos. El objetivo ...
  • The quiet and underappreciated rise of drug-resistant invasive fungal pathogens 

    Arastehfar, Amir; Lass-Flörl, Cornelia; Garcia-Rubio, Rocio; Daneshnia, Farnaz; Ilkit, Macit; Boekhout, Teun; Gabaldon, Toni; Perlin, David S. (MDPI, 2020-08)
    Article
    Open Access
    Human fungal pathogens are attributable to a significant economic burden and mortality worldwide. Antifungal treatments, although limited in number, play a pivotal role in decreasing mortality and morbidities posed by ...
  • Tracking of antibiotic resistance transfer and rapid plasmid evolution in a hospital setting by Nanopore sequencing 

    Peter, Silke; Bosio, Mattia; Gross, Caspar; Bezdan, Daniela; Gutierrez, Javier; Oberhettinger, Philipp; Liese, Jan; Vogel, Wichard; Dörfel, Daniela; Berger, Lennard; Marschal, Matthias; Willmann, Matthias; Gut, Ivo; Gut, Marta; Autenrieth, Ingo; Ossowski, Stephan (American Society for Microbiology, 2020)
    Article
    Open Access
    Infections with multidrug-resistant bacteria often leave limited or no treatment options. The transfer of antimicrobial resistance genes (ARG) carrying plasmids between bacterial species by horizontal gene transfer represents ...
  • Patterns and impacts of nonvertical evolution in eukaryotes: a paradigm shift 

    Gabaldon, Toni (Wiley, 2020)
    Article
    Open Access
    Abstract Evolution of eukaryotic species and their genomes has been traditionally understood as a vertical process in which genetic material is transmitted from parents to offspring along a lineage, and in which genetic ...
  • Cis and trans effects differentially contribute to the evolution of promoters and enhancers 

    Mattioli, Kaia; Oliveros, Winona; Gerhardinger, Chiara; Andergassen, Daniel; Maass, Philipp G.; Rinn, John L.; Melé, Marta (Springer Nature, 2020-08-20)
    Article
    Open Access
    Background Gene expression differences between species are driven by both cis and trans effects. Whereas cis effects are caused by genetic variants located on the same DNA molecule as the target gene, trans effects are ...
  • Modeling of protein complexes and molecular assemblies with pyDock 

    Rosell, Mireia; Rodríguez-Lumbreras, Luis Angel; Fernández-Recio, Juan (Springer Link, 2020)
    Part of book or chapter of book
    Restricted access - publisher's policy
    The study of the 3D structural details of protein interactions is essential to understand biomolecular functions at the molecular level. In this context, the limited availability of experimental structures of protein–protein ...

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