Life Sciences
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Threats from the Candida parapsilosis complex: the surge of multidrug resistance and a hotbed for new emerging pathogens
(American Society for Microbiology, 2024-11-07)
Article
Open AccessCandida parapsilosis is a common agent of candidiasis that has gained increased attention in recent years, culminating with its recent consideration as a high-priority fungal pathogen by the World Health Organization. ... -
The ELIXIR Biodiversity Community: Understanding short- and long-term changes in biodiversity
(F1000 Research Ltd, 2024)
Article
Open AccessBiodiversity loss is now recognised as one of the major challenges for humankind to address over the next few decades. Unless major actions are taken, the sixth mass extinction will lead to catastrophic effects on the ... -
Profiling Bacteria in the Lungs of Patients with Severe Influenza Versus COVID-19 with or without Aspergillosis
(American Thoracic Society, 2024)
Article
Open AccessRationale: The influence of the lung bacterial microbiome, including potential pathogens, in patients with influenza-associated pulmonary aspergillosis (IAPA) or coronavirus disease (COVID-19)–associated pulmonary aspergillosis ... -
Trustworthy AI. The AI4EU approach
(PoS - Proceedings of Science, 2019)
Conference report
Open AccessThe Ethical, Legal, Socio-Economic and Cultural aspects of Artificial Intelligence have been a burning issue over the last five years. In the EU, especially this has been brought into focus by the High-Level Experts Group ... -
MONFIT: multi-omics factorization-based integration of time-series data sheds light on Parkinson’s disease
(Oxford University Press, 2024-10)
Article
Open AccessParkinson’s disease (PD) is a severe and complex multifactorial neurodegenerative disease with still elusive pathophysiology preventing the development of curative treatments. Molecular deep phenotyping by longitudinal ... -
LaFresCat: a Catalan multi-accent speech dataset for text-to-speech
(International Speech Communication Association (ISCA), 2024)
Conference lecture
Open AccessCurrent generative text-to-speech (TTS) models are very robust and capable of learning the phonetics of a language almost perfectly. To do so, it remains crucial that the speech data used to train such models covers all ... -
Graphlet-based hyperbolic embeddings capture evolutionary dynamics in genetic networks
(Oxford University Press, 2024-11-04)
Article
Open AccessMotivation Spatial Analysis of Functional Enrichment (SAFE) is a popular tool for biologists to investigate the functional organization of biological networks via highly intuitive 2D functional maps. To create these maps, ... -
Unlocking a Key Residue in a Lipase for Efficient Polyethylene Terephthalate (PET) Hydrolysis and Influencing Depolymerization Product Profiles
(Wiley, 2024-09-05)
Article
Open AccessPolyethylene terephthalate (PET) pollution is a global challenge. Advancing the bioprospecting of PET-degrading enzymes through metagenomics and using computational and functional methods to identify key positions influencing ... -
Artificial intelligence across Europe: a study on awareness, attitude and trust
(Institute of Electrical and Electronics Engineers (IEEE), 2024)
Article
Open AccessThis paper presents the results of an extensive study investigating the opinions on Artificial Intelligence (AI) of a sample of 4,006 European citizens from eight distinct countries (France, Germany, Italy, Netherlands, ... -
ONCOLINER: A new solution for monitoring, improving, and harmonizing somatic variant calling across genomic oncology centers
(Elsevier, 2024-09-11)
Article
Open AccessThe characterization of somatic genomic variation associated with the biology of tumors is fundamental for cancer research and personalized medicine, as it guides the reliability and impact of cancer studies and genomic-based ... -
Comparison between 16S rRNA and shotgun sequencing in colorectal cancer, advanced colorectal lesions, and healthy human gut microbiota
(BioMed Central (BMC), 2024)
Article
Open AccessBackground Gut dysbiosis has been associated with colorectal cancer (CRC), the third most prevalent cancer in the world. This study compares microbiota taxonomic and abundance results obtained by 16S rRNA gene sequencing ... -
Long-term stability of acquired drug resistance and resistance associated mutations in the fungal pathogen Nakaseomyces glabratus (Candida glabrata)
(Frontiers Media, 2024)
Article
Open AccessThe limited number of available antifungal drugs and the increasing number of fungal isolates that show drug or multidrug resistance pose a serious medical threat. Several yeast pathogens, such as Nakaseomyces glabratus ...