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A randomized pilot trial to evaluate the benefit of the concomitant use of atorvastatin and Raltegravir on immunological markers in protease-inhibitor-treated subjects living with HIV
(Public Library of Science (PLOS), 2020-09-17)
Article
Open AccessObjective Optimization of antiretroviral therapy and anti-inflammatory treatments, such as statins, are among the strategies aimed at reducing metabolic disorders, inflammation and immune activation in people living ... -
UAV, digital processing and vectorization techniques applied to building condition assessment and follow-up
(2020-12-09)
Article
Open AccessThe aim of the paper is to explain the basic principles of carrying out an inventory and follow-up of buildings and their condition assessment, by using the Full Interactive Visualization Method for Building Condition ... -
Using the STROBE statement: survey findings emphasized the role of journals in enforcing reporting guidelines
(2019-12-01)
Article
Open AccessObjectives The objective of the study was to identify factors affecting the use of the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement, specifically authors’ attitudes toward and ... -
A systematic review describes models for recruitment prediction at the design stage of a clinical trial
(2019-11-01)
Article
Open AccessPatient recruitment in clinical trials is challenging with failure to recruit to time and target sample size common. This may be caused by unanticipated problems or by overestimation of the recruitment rate. This study is ... -
A hazard ratio was estimated by a ratio of median survival times, but with considerable uncertainty
(2014-10-01)
Article
Open AccessObjectives: To evaluate the empirical concordance between the hazard ratio (HR) and the median ratio (MR) in survival cancer studies. Study Design and Setting: We selected all cancer survival articles from the New England ... -
Model selection for mixture-based clustering for ordinal data
(2016-12)
Article
Restricted access - publisher's policyOne of the key questions in the use of mixture models concerns the choice of the number of components most suitable for a given data set. In this paper we investigate answers to this problem in the context of likelihood-based ... -
Are environmental pollution and biodiversity levels associated to the spread and mortality of COVID-19? A four-month global analysis
(2021-02-15)
Article
Restricted access - publisher's policyOn March 12th, 2020, the WHO declared COVID-19 as a pandemic. The collective impact of environ-mental and ecosystem factors, as well as biodiversity, on the spread of COVID-19 and its mortalityevolution remain empirically ... -
A goodness-of-fit test for the ordered stereotype model
(2016-11-10)
Article
Open AccessThis paper presents a new goodness-of-fit test for an ordered stereotype model used for an ordinal response variable. The proposed test is based on the well-known Hosmer–Lemeshow test and its version for the proportional ... -
An iterative method to protect the type I error rate in bioequivalence studies under two-stage adaptive 2×2 crossover designs
(2021-01)
Article
Restricted access - publisher's policyBioequivalence studies are the pivotal clinical trials submitted to regulatory agen- cies to support the marketing applications of generic drug products. Average bioequivalence (ABE) is used to determine whether the mean ... -
Estimation of spatial sampling effort based on presence-only data over a class of species
(2015-03-10)
Article
Restricted access - publisher's policySampling bias contained in data of biological surveys is very common. Bias is clearly a function of roads, cities, rivers, or other physical features that determines accessibility of collectors, and many data sets of species ... -
Covid-19: la malinterpretación de los datos de la pandemia daña la confianza del público
(2020-11-04)
Article
Open Access -
Biclustering models for two-mode ordinal data
(2016-09)
Article
Open AccessThe work in this paper introduces finite mixture models that can be used to simultaneously cluster the rows and columns of two-mode ordinal categorical response data, such as those resulting from Likert scale responses. ...
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