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Recent Submissions
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Impact of medication adherence on mortality and cardiovascular morbidity: a population-based cohort study. IMPACT study
(2018-03-09)
Article
Restricted access - publisher's policy -
Efficacy of high doses of penicillin versus amoxicillin in the treatment of uncomplicated community acquired pneumonia in adults. A non-inferiority controlled clinical trial
(2017-10)
Article
Open AccessCommunity-acquired pneumonia; Randomized controlled trial; Penicillin; Amoxicillin; Adults -
Communication key performance indicators for selecting construction project bidders
(2017-11)
Article
Open AccessIt is vital to select the right project bidders, as this affects the success of a project. Although there are numerous methods for assessing bidders, communication is rarely taken into account. This paper discusses the ... -
FHtest: an R package for the comparison of survival curves with censored data
(2017-11)
Article
Open AccessThe Fleming-Harrington class for right-censored data was first introduced by Harrington and Fleming (1982). This class is widely used in survival analysis studies and it is a subset of the so-called weighted logrank test ... -
The STROBE extensions: protocol for a qualitative assessment of content and a survey of endorsement
(2018-02-16)
Article
Open AccessIntroduction The STrengthening the Reporting of OBservational studies in Epidemiology (STROBE) Statement was developed in response to inadequate reporting of observational studies. In recent years, several extensions to ... -
On the selection of significant variables in a model for the deteriorating process of facades
(Institute of Physics (IOP), 2017)
Article
Open AccessIn previous works the authors of this paper have introduced a predictive system that uses survival analysis techniques for the study of time-to-failure in the facades of a building stock. The approach is population based, ... -
Non-linear formation of EtG and FAEEs after controlled administration of low to moderate doses of ethanol
(2017-09-01)
Article
Restricted access - publisher's policyAims Ethyl glucuronide (EtG) and fatty acid ethyl esters (FAEEs) are non-oxidative metabolites of alcohol that can be detected in conventional and non-conventional biological matrices for longer periods than alcohol. The ... -
Role of PARP activity in lung cancer-induced cachexia: effects on muscle oxidative stress, proteolysis, anabolic markers, and phenotype
(2017-12)
Article
Restricted access - publisher's policyStrategies to treat cachexia are still at its infancy. Enhanced muscle protein breakdown and ubiquitin-proteasome system are common features of cachexia associated with chronic conditions including lung cancer (LC). ... -
Two-stage designs versus European scaled average designs in bioequivalence studies for highly variable drugs: which to choose?
(2017-12)
Article
Restricted access - publisher's policyThe usual approach to determine bioequivalence for highly variable drugs is scaled average bioequivalence, which is based on expanding the limits as a function of the within-subject variability in the reference formulation. ... -
Selection of composite binary endpoints in clinical trials
(2017-10-12)
Article
Restricted access - publisher's policyThe choice of a primary endpoint is an important issue when designing a clinical trial. It is common to use composite endpoints as a primary endpoint because it increases the number of observed events, captures more ... -
Pharmacokinetics in morbid obesity: influence of two bariatric surgery techniques on paracetamol and caffeine metabolism
(2017-05-30)
Article
Restricted access - publisher's policyThe purpose of the study was to study the impact of the two most common bariatric surgery techniques on paracetamol pharmacokinetics (a marker of gastric emptying) and caffeine metabolism (a marker of liver function). In ... -
Are CONSORT checklists submitted by authors adequately reflecting what information is actually reported in published papers?
(2018-01-29)
Article
Open AccessBackground: Compulsory submission of a checklist from the relevant reporting guideline is one of the most widespread journal requirements aiming to improve completeness of reporting. However, the current suboptimal levels ...
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