El GRBIO és un grup interdisciplinari amb interessos diversos tant metodològics com aplicats amb una base comuna que és l'aplicació rigorosa de l'estadística a problemes suscitats a les Ciències de la Vida i de la Salut. Les activitats científiques les agrupem en tres àmbits:
1) Assajos clínics: aportacions metodològiques en les fases de disseny i modelat estadístic;
2) Anàlisi integrativa de dades òmiques: mètodes estadístics multivariants i de "machine learning";
3) Desenvolupament d'eines estadístiques i informàtiques per l'explotació dels resultats de la recerca biomèdica.
Mencionem també les contribucions a l'anàlisi i representació de dades multivariants, a l'anàlisi de dades de supervivència amb censura en un interval, a l'optimització del disseny de fàrmacs amb simulació i a la resolució de problemes aplicats en camps com VIH/SIDA, oncologia, neurociències, cardiologia o immunologia.

Research Group in Biostatistics and Bioinformatics (GRBIO) combines researchers with solid basis in statistics, good background in mathematics and/or computer science and significant knowledge of the scientific field of application in which we collaborate. GRBIO aims to address interdisciplinary problems by merging Biostatistics and Bioinformatics knowledge and to make relevant scientific contributions on health areas where closer collaboration is needed.

Research Group in Biostatistics and Bioinformatics (GRBIO) combines researchers with solid basis in statistics, good background in mathematics and/or computer science and significant knowledge of the scientific field of application in which we collaborate. GRBIO aims to address interdisciplinary problems by merging Biostatistics and Bioinformatics knowledge and to make relevant scientific contributions on health areas where closer collaboration is needed.

Recent Submissions

  • Retirements of professional tennis players in second- and third-tier tournaments on the ATP and WTA tours 

    Palau, Maria; Baiget Vidal, Ernest; Cortés Martínez, Jordi; Martínez, Joan; Crespo Celda, Miguel; Casals Toquero, Martí (Public Library of Science (PLOS), 2024-06-03)
    Article
    Open Access
    The demands of professional tennis, including physical and psychological aspects, contribute to the frequency of retirements at elite levels of the sport. The aim of this study was to analyze epidemiological patterns and ...
  • Research and numerical assessment of design and construction errors in the swimming pool facility structures 

    Pawlowicz, Joanna A.; Skotnicka-Siepsiak, Aldona; Szelag, Romuald; Krentowski, Janusz; Serrat Piè, Carles (2023)
    Conference lecture
    Open Access
    The proper performance of swimming pool halls depends on many factors. An extremely important one is the ventilation system, which is supposed to provide, among other things, the prevention of high temperatures, excessive ...
  • Group-by-treatment interaction effects in comparative bioavailability studies 

    Schütz, Helmut; Burger, Divan Aristo; Cobo Valeri, Erik; Dubins, David D.; Farkás, Tibor; Labes, Detlew; Lang, Benjamin; Ocaña Rebull, Jordi; Ring, Arne; Shitova, Anastasia; Stus, Volodymyr; Tomashevskiy, Michael (2024-04-17)
    Article
    Open Access
    Comparative bioavailability studies often involve multiple groups of subjects for a variety of reasons, such as clinical capacity limitations. This raises questions about the validity of pooling data from these groups in ...
  • N20 potential and imaging biomarkers of functional recovery in acute ischemic stroke patients and EVT 

    Martínez Piñeiro, Alicia; Lucente, Giuseppe; Hernández Pérez, María; Cortés Martínez, Jordi; Arbex Bassols, Andrea; Gomis Cortina, Meritxell; Dorado Bouix, Laura; Pérez de la Ossa, Natalia; Ramos Fransi, Alba; Almendrote Muñoz, Miriam; Castaño, Carlos; Remollo Friedemann, Sebastián; Garcia Sort, Rosa; Cuadras Collsamata, Patricia; Millán Torné, Mònica; Dávalos Errando, Antoni (2023)
    Conference lecture
    Open Access
    Introduction: PROMISE trial has shown high predictive accuracy of the N20 somatosensory evoked potential (SEP) response on functional recovery in patients with AIS undergoing endovascular thrombectomy (EVT). This secondary ...
  • Research and numerical assessment of design and construction errors in the swimming pool facility structures 

    Skotnicka-Siepsiak, Aldona; Pawlowicz, Joanna A.; Szelag, Romuald; Krentowski, Janusz; Serrat Piè, Carles (Elsevier, 2024-05-01)
    Article
    Open Access
    Swimming pools are characterized by high humidity, high temperature, an aggressive environment caused by disinfection processes, high energy consumption, and extensive technical infrastructure. As a result, these facilities ...
  • COVID-19 patient profiles over four waves in Barcelona metropolitan area: a clustering approach 

    Fernández Martínez, Daniel; Pérez Álvarez, Nuria; Molist Señé, Gemma (Public Library of Science (PLOS), 2024-05-07)
    Article
    Open Access
    Objectives: Identifying profiles of hospitalized COVID-19 patients and explore their association with different degrees of severity of COVID-19 outcomes (i.e. in-hospital mortality, ICU assistance, and invasive mechanical ...
  • Reverse engineering as a non-invasive examining method of the water tower brick structure condition 

    Pawlowicz, Joanna A.; Knyziak, Piotr; Krentowski, Janusz; Mackiewicz, Monika; Skotnicka-Siepsiak, Aldona; Serrat Piè, Carles (Elsevier, 2024-04-02)
    Article
    Open Access
    Reverse engineering is a method of obtaining information about the geometry of an existing object. To obtain such information, among others: 3D laser scanning is used. The result of measurements using this method is a point ...
  • Determining the degree of deformation in rain drainage installations through point cloud modelling 

    Pawlowicz, Joanna A.; Skotnicka-Siepsiak, Aldona; Serrat Piè, Carles (2023)
    Article
    Open Access
    Buildings are often complex and hindered by identifying and measuring deformation in both the building itself and its elements. However, we have the assistance of 3D laser scanning technology which allows us to collect ...
  • Moving from an ERASMUS+ innovation project on mathematics in engineering education to the teaching practice: Learnings from the UPC experience 

    Serrat Piè, Carles; Estela Carbonell, M. Rosa; Bruguera Padró, Maria Montserrat; Pantazi, Chara (Institute of Electrical and Electronics Engineers (IEEE), 2023)
    Conference report
    Open Access
    The main aim of this Research-to-Practice Workin-Progress paper is to analyze, discuss and share with the academic community the application of the outputs of research and innovation projects to the real teaching practice ...
  • Classification systems for the built environment: a cornerstone for the long-term performance analysis 

    Serrat Piè, Carles; Royano García, Verónica; Gibert Armengol, Vicente; Rapinski, Jacek (Scipedia, 2023)
    Conference report
    Open Access
    In the long-term performance analysis of the built environment, classification systems are seen as a key consideration. When classifying residential building objects, characteristics such as accuracy, exhaustivity, and ...
  • Survival analysis with censored data: a further twist on ignorability conditions 

    Oller Piqué, Ramón; Gómez Melis, Guadalupe (Taylor & Francis Group, 2024-02-04)
    Article
    Open Access
    A key assumption for the application of methods concerning censored data is that the random nature of the censoring mechanism should be ignorable when making likelihood-based inferences. The constant-sum property is an ...
  • Burnout in residents during the first wave of the COVID-19 pandemic: a systematic review and meta-analysis 

    Navinés, Ricard; Olivé, Victòria; Hidalgo Mazzei, Diego; Langohr, Klaus; Vieta, E.; Martín-Santos, Rocío (Frontiers Media SA, 2024-01-24)
    Article
    Open Access
    The high prevalence of burnout in resident physicians is expected to have increased as a result of the expansion of the pandemic. We conducted a systematic review with a meta-analysis of studies conducted during the first ...

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