El GRBIO és un grup interdisciplinari amb interessos diversos tant metodològics com aplicats amb una base comuna que és l'aplicació rigorosa de l'estadística a problemes suscitats a les Ciències de la Vida i de la Salut. Les activitats científiques les agrupem en tres àmbits:
1) Assajos clínics: aportacions metodològiques en les fases de disseny i modelat estadístic;
2) Anàlisi integrativa de dades òmiques: mètodes estadístics multivariants i de "machine learning";
3) Desenvolupament d'eines estadístiques i informàtiques per l'explotació dels resultats de la recerca biomèdica.
Mencionem també les contribucions a l'anàlisi i representació de dades multivariants, a l'anàlisi de dades de supervivència amb censura en un interval, a l'optimització del disseny de fàrmacs amb simulació i a la resolució de problemes aplicats en camps com VIH/SIDA, oncologia, neurociències, cardiologia o immunologia.

Research Group in Biostatistics and Bioinformatics (GRBIO) combines researchers with solid basis in statistics, good background in mathematics and/or computer science and significant knowledge of the scientific field of application in which we collaborate. GRBIO aims to address interdisciplinary problems by merging Biostatistics and Bioinformatics knowledge and to make relevant scientific contributions on health areas where closer collaboration is needed.

Research Group in Biostatistics and Bioinformatics (GRBIO) combines researchers with solid basis in statistics, good background in mathematics and/or computer science and significant knowledge of the scientific field of application in which we collaborate. GRBIO aims to address interdisciplinary problems by merging Biostatistics and Bioinformatics knowledge and to make relevant scientific contributions on health areas where closer collaboration is needed.

Recent Submissions

  • Compulsive sexual behavior online and non-online in adult male patients and healthy controls: comparison in sociodemographic, clinical, and personality variables 

    González Bueso, Vega; Santamaría, Juan José; Caro Pérez, Oriol; Fernández Martínez, Daniel; Baño-Alcazar, Marta; Jiménez Murcia, Susana; Hakansson, Anders; del Pino Gutiérrez, Amparo; Ribas, Joan (Frontiers Media SA, 2022-05-03)
    Article
    Open Access
    Background and Aims: Compulsive sexual behavior (CSB) is characterized by a persistent pattern of failure to control sexual impulses, resulting in repetitive sexual behavior over a prolonged period that causes marked ...
  • Use of GPS to measure external load and estimate the incidence of muscle injuries in men’s football: a novel descriptive study 

    Guitart, Marc; Casals Toquero, Martí; Casamichana, David; Cortés Martínez, Jordi; Valle, Francesc Xavier; McCall, Alan; Cos, Francesc; Rodas, Gil (Public Library of Science (PLOS), 2022-02-04)
    Article
    Open Access
    Measurement of external load in players provides objective information to optimise the weekly balance between training and recovery to improve performance and prevent injuries. Our aim was to evaluate the incidence of ...
  • Detection of adulterations in fruit juices using machine learning methods over FT-IR spectroscopic data 

    Pérez Calle, José Luis; Ferreiro González, Marta; Ruiz-Rodríguez, Ana; Fernández Martínez, Daniel; Palma, Miguel (Multidisciplinary Digital Publishing Institute (MDPI), 2022-03)
    Article
    Open Access
    Fruit juices are one of the most adulterated beverages, usually because of the addition of water, sugars, or less expensive fruit juices. This study presents a method based on Fourier transform infrared spectroscopy (FT-IR), ...
  • Daidzein modulates cocaine-reinforcing effects and cue-induced cocaine reinstatement in CD-1 male mice 

    Martin, Miquel; Langohr, Klaus; De la Torre Fornell, Rafael; Farré Albadalejo, Magí; Cabrera Ortega, Roberto; Gutiérrez Martos, Miriam; Maldonado López, Rafael (2021-04-11)
    Article
    Open Access
    Rationale Cocaine addiction is a chronic relapsing disorder that lacks of an effective treatment. Isoflavones are a family of compounds present in different plants and vegetables like soybeans that share a common chemical ...
  • Neonatal feeding trajectories in mothers with bipolar disorder taking lithium: pharmacokinetic data 

    Imaz, María Luisa; Langohr, Klaus; Torra, Mercè; Soy, Dolors; Garcia Esteve, Lluïsa; Martin Santos, Rocío (Frontiers Media SA, 2021-09-22)
    Article
    Open Access
    Purpose: Women who take lithium during pregnancy and continue after delivery may choose to breastfeed, formula feed, or mix these options. The aim of the study was to evaluate the neonatal lithium serum concentrations based ...
  • Importancia del diseño experimental 

    Langohr, Klaus (Elsevier, 2021-12)
    Article
    Open Access
    El diseño balanceado es una opción útil y eficiente para evitar la confusión de efectos en un estudio clínico. En nuestro ejemplo, si la intervención y el tamaño del cálculo renal son independientes, las estimaciones de ...
  • Sesgo de selección 

    Langohr, Klaus (Elsevier, 2021-12)
    Article
    Open Access
  • Confusión de efectos 

    Langohr, Klaus (Elsevier, 2021-12)
    Article
    Open Access
  • 5È. Audit clínic de l'ictus. Catalunya 2018/19 

    Salvat Plana, Mercè; Pérez de la Ossa, Natalia; Cortés Martínez, Jordi; Ayesta, Mercè; Gallofré, Guillem (2021-02-01)
    Research report
    Open Access
    S’han auditat 4.008 casos ingressats per ictus agut entre 2018 i 2019. El període d’estudi s’ha ampliat a 6 mesos, en períodes de 1 mes i mig al llarg de 12 mesos, similars per a tots els centres. L’obtenció prospectiva ...
  • Consumo de substancias durante el embarazo y dimensiones de personalidad 

    Imaz, María Luisa; Navinés, Ricard; Gelabert, Estel; Fonseca, Francina; Gutiérrez Zotes, Alfonso; Guillamat, Roser; Langohr, Klaus; Canellas, Francesca; Gornemann, Inmaculada; Costas, Javier (2020-12-02)
    Article
    Open Access
    Este estudio evalúa los patrones de consumo de substancias durante el embarazo y las dimensiones de personalidad asociadas, en una muestra multicéntrica de 1804 mujeres de población general. En el 2-3 día posparto, completaron ...
  • A class of two-sample nonparametric statistics for binary and time-to-event outcomes 

    Bofill Roig, Marta; Gómez Melis, Guadalupe (2022)
    Article
    Open Access
    We propose a class of two-sample statistics for testing the equality of proportions and the equality of survival functions. We build our proposal on a weighted combination of a score test for the difference in proportions ...
  • Monotherapy with boosted PIs as an ART simplification strategy in clinical practice 

    Santos, Jose R.; Llibre, Josep M.; Berrio Galan, Daniel; Bravo, Isabel; Miranda, Cristina; Pérez Álvarez, Susana; Pérez Álvarez, Nuria; Paredes Deirós, Roger; Clotet Sala, Bonaventura; Molto Marhuenda, Jose (2015-04-01)
    Article
    Restricted access - publisher's policy
    Background: Data on the efficacy of simplifying therapy using darunavir/ritonavir and lopinavir/ritonavir monotherapy in clinical practice remain limited.; Methods: A retrospective single-centre study including patients ...

View more