Enviaments recents

  • Spatial distribution of calcium sparks determines their ability to induce afterdepolarizations in human atrial myocytes 

    Tarifa Lora, Carmen; Vallmitjana Lees, Alexander; Jiménez Sábado, Verónica; Marchena Angos, Miquel; Llach, Anna; Herraiz Martínez, Adela; Nolla Colomer, Carme; Ginel Iglesias, Antonino; Montiel Dacosta, José Antonio; Ciruela, Francisco; Echebarría Domínguez, Blas; Benítez Iglesias, Raúl; Cinca Cuscullola, Juan Maria; Hove-Madsen, Leif (Elsevier, 2023-01)
    Article
    Accés obert
    Analysis of the spatio-temporal distribution of calcium sparks showed a preferential increase in sparks near the sarcolemma in atrial myocytes from patients with atrial fibrillation (AF), linked to higher ryanodine receptor ...
  • Increased Ca2+ transient underlies RyR2-related left ventricular noncompaction 

    Ni, Mingke; Li, Yanhui; Wei, Jinhong; Song, Zhenpeng; Wang, Hui; Yao, Jinjing; Chen, Yong-Xiang; Belke, Darrell; Estillore, John Paul; Wang, Ruiwu; Vallmitjana Lees, Alexander; Benítez Iglesias, Raúl; Hove Madsen, Leif; Feng, Wei; Chen, Ju (2023-07-07)
    Article
    Accés obert
    Background: A loss-of-function cardiac ryanodine receptor (RyR2) mutation, I4855M+/–, has recently been linked to a new cardiac disorder termed RyR2 Ca2+ release deficiency syndrome (CRDS) as well as left ventricular ...
  • Single-cell Bayesian deconvolution 

    Torregrosa Cortés, Gabriel; Oriola Santandreu, David; Trivedi, Vikas; García Ojalvo, Jordi (Elsevier, 2023-10-20)
    Article
    Accés obert
    Individual cells exhibit substantial heterogeneity in protein abundance and activity, which is frequently reflected in broad distributions of fluorescently labeled reporters. Since all cellular components are intrinsically ...
  • TS-CNN: a three-tier self-interpretable CNN for multi-region medical image classification 

    Ashwath, V. A.; Okkath Krishnanunni, Sikha; Benítez Iglesias, Raúl (Institute of Electrical and Electronics Engineers (IEEE), 2023-07-31)
    Article
    Accés obert
    Medical image classification is critical, where reliability and transparency are crucial for the safe and accurate diagnosis of diseases. Deep Convolutional Neural Networks (DCNNs) are widely used in medical image ...
  • Light distribution in tanks with the green seaweed Ulva ohnoi: effect of stocking density, incident irradiance and chlorophyll content 

    Ginovart Gisbert, Marta; Pintado Valverde, José; Del Olmo Berenguer, Gonzalo; Cremades Ugarte, Javier; Jiménez de Ridder, Patrícia; Masaló Llorà, Ingrid (2023-09-01)
    Article
    Accés restringit per política de l'editorial
    eaweed farming is an interesting technique to meet the future global food demand. However, it is essential to increase productivity in order to reduce the land surface required and make tank-based production more cost ...
  • Semi-automatic GUI platform to characterize brain development in preterm children using ultrasound images 

    Rabanaque, David; Regalado, Maria; Benítez Iglesias, Raúl; Rabanaque Rodríguez, Sonia; Agut, Thais; Carreras, Núria; Mata Miquel, Cristian (2023-07-15)
    Article
    Accés obert
    The third trimester of pregnancy is the most critical period for human brain development, during which significant changes occur in the morphology of the brain. The development of sulci and gyri allows for a considerable ...
  • Ante-hoc generation of task-agnostic interpretation maps 

    Guna R. T., Akash; Okkath Krishnanunni, Sikha; Benítez Iglesias, Raúl (Institute of Electrical and Electronics Engineers (IEEE), 2023-06-23)
    Article
    Accés obert
    Existing explainability approaches for convolutional neural networks (CNNs) are mainly applied after training (post-hoc) which is generally unreliable. Ante-hoc explainers trained simultaneously with the CNN are more ...
  • Using in silico perturbational approach to identify critical areas in schizophrenia 

    Vila Vidal, Manel; Kringelbach, Morten L.; Deco, Gustavo (2023-06-15)
    Article
    Accés restringit per política de l'editorial
    Schizophrenia is a debilitating neuropsychiatric disorder whose underlying correlates remain unclear despite decades of neuroimaging investigation. One contentious topic concerns the role of global signal (GS) fluctuations ...
  • Transition from the old to the new viral normality: Where are we? 

    Perramon Malavez, Aida; López de Rioja, Víctor; López Codina, Daniel; Prats Soler, Clara (2023-05)
    Article
    Accés obert
    Background: The seasonality of respiratory diseases caused by viruses has been altered by the emergence of SARS-CoV-2. After a period of almost no bronchiolitis and influenza diagnoses, these seasonal infectious diseases ...
  • Mortality in Catalonia during the summer of 2022 and its relation with high temperatures and COVID-19 cases 

    Coma, Ermengol; Pino González, David; Moras Planes, Núria; Mora, Núria; Fina Avilés, Francesc; Perramon Malavez, Aida; Prats Soler, Clara; Medina, Manuel; Planella, Antoni; Mompart Penina, Anna; Mendioroz, Jacobo; Cabezas Martínez, Carlos (Frontiers Media SA, 2023-05-19)
    Article
    Accés obert
    Purpose: To analyse the association between the mortality during the summer 2022 and either high temperatures or the COVID-19 wave with data from the Catalan Health Care System (7.8 million people). Methods: We performed ...
  • Multiscale image analysis of calcium dynamics in cardiac myocytes 

    Vallmitjana Lees, Alexander; Benítez Iglesias, Raúl (2022-06-01)
    Article
    Accés obert
    Cardiac myocytes are the muscle cells that build up heart tissue and provide the mechanical action to pump blood by synchronously contracting at every heartbeat. Heart muscle contraction is regulated by intracellular calcium ...
  • Pitx2c deficiency confers cellular electrophysiological hallmarks of atrial fibrillation to isolated atrial myocytes 

    Tarifa Lora, Carmen; Serra, Selma A.; Herraiz Martínez, Adela; Lozano Velasco, Estefanía; Benítez Iglesias, Raúl; Aránega Jiménez, Amelia; Franco Jaime, Diego; Hove Madsen, Leif (Elsevier, 2023-06-01)
    Article
    Accés obert
    Aims Atrial fibrillation (AF) has been associated with altered expression of the transcription factor Pitx2c and a high incidence of calcium release-induced afterdepolarizations. However, the relationship between Pitx2c ...

Mostra'n més