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Effect of genetically predicted sclerostin on cardiovascular biomarkers, risk factors, and disease outcomes
(2024-11-13)
Article
Open AccessSclerostin inhibitors protect against osteoporotic fractures, but their cardiovascular safety remains unclear. We conducted a cis-Mendelian randomisation analysis to estimate the causal effect of sclerostin levels on ... -
Effectiveness of nirsevimab immunoprophylaxis against respiratory syncytial virus-related outcomes in hospital and primary care settings: a retrospective cohort study in infants in Catalonia (Spain)
(2024-01-01)
Article
Open AccessBackground In Catalonia, infants under 6¿months old were eligible to receive nirsevimab, a novel monoclonal antibody against respiratory syncytial virus (RSV). We aimed to analyse nirsevimab’s effectiveness across primary ... -
Introduction of nirsevimab in Catalonia, Spain: description of the incidence of bronchiolitis and respiratory syncytial virus in the 2023/2024 season
(Springer, 2024-09-28)
Article
Open AccessRespiratory syncytial virus (RSV) causes most of the cases of bronchiolitis and thousands of deaths annually, particularly in infants less than 6 months old. In Catalonia (Spain), infants born between April 2023 and March ... -
Development of a low-cost robotized 3D-prototype for automated optical microscopy diagnosis: an open-source system
(Public Library of Science (PLOS), 2024-06-21)
Article
Open AccessIn a clinical context, conventional optical microscopy is commonly used for the visualization of biological samples for diagnosis. However, the availability of molecular techniques and rapid diagnostic tests are reducing ... -
Overview on cognitive impairment in psychotic disorders: from impaired microcircuits to dysconnectivity
(Elsevier, 2024-07-01)
Article
Open AccessSchizophrenia's cognitive deficits, often overshadowed by positive symptoms, significantly contribute to the disorder's morbidity. Increasing attention highlights these deficits as reflections of neural circuit dysfunction ... -
A comparative study between a power and a connectivity sEEG biomarker for seizure-onset zone identification in temporal lobe epilepsy
(2024-11)
Article
Open AccessBackground: Ictal stereo-encephalography (sEEG) biomarkers for seizure onset zone (SOZ) localization can be classified depending on whether they target abnormalities in signal power or functional connectivity between ... -
Thalamocortical interactions shape hierarchical neural variability during stimulus perception
(Elsevier, 2024-07-19)
Article
Open AccessThe brain is organized hierarchically to process sensory signals. But, how do functional connections within and across areas contribute to this hierarchical order? We addressed this problem in the thalamocortical network, ... -
Mathematical modeling of SARS-CoV-2 variant substitutions in European countries: transmission dynamics and epidemiological insights
(Frontiers Media SA, 2024-05-15)
Article
Open AccessBackground: Countries across Europe have faced similar evolutions of SARS-CoV-2 variants of concern, including the Alpha, Delta, and Omicron variants.Materials and methods: We used data from GISAID and applied a robust, ... -
Severity of Omicron subvariants and vaccine impact in Catalonia, Spain
(2024-04-27)
Article
Open AccessIn the current COVID-19 landscape dominated by Omicron subvariants, understanding the timing and efficacy of vaccination against emergent lineages is crucial for planning future vaccination campaigns, yet detailed studies ... -
Country-report pattern corrections of new cases allow accurate 2-week predictions of COVID-19 evolution with the Gompertz model
(Springer, 2024-05-11)
Article
Open AccessAccurate short-term predictions of COVID-19 cases with empirical models allow Health Officials to prepare for hospital contingencies in a two–three week window given the delay between case reporting and the admission of ... -
Subconductance states in a semimicroscopic model for a tetrameric pore
(American Institute of Physics (AIP), 2024-04-02)
Article
Open AccessA physical model for a structured tetrameric pore is studied. The pore is modeled as a device composed of four subunits, each one exhibiting two possible states (open and closed). The pore is located within a membrane that ... -
A mixture of mobility and meteorological data provides a high correlation with COVID-19 growth in an infection-naive population: a study for Spanish provinces
(Frontiers Media SA, 2024-03-07)
Article
Open AccessIntroduction: We use Spanish data from August 2020 to March 2021 as a natural experiment to analyze how a standardized measure of COVID-19 growth correlates with asymmetric meteorological and mobility situations in 48 ...
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