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  • Ca2+-CaM Dependent Inactivation of RyR2 Underlies Ca2+ Alternans in Intact Heart 

    Guo, Wenting; Benítez Iglesias, Raúl; Hove-Madsen, Leif; Álvarez Lacalle, Enrique; Echebarría Domínguez, Blas (2021-02-19)
    Article
    Open Access
    Rationale: Ca2+ alternans plays an essential role in cardiac alternans that can lead to ventricular fibrillation, but the mechanism underlying Ca2+ alternans remains undefined. Increasing evidence suggests that Ca2+ ...

  • The ethical use of high-performance computing and artificial intelligence: fighting COVID-19 at Barcelona Supercomputing Center 

    Cortés García, Claudio Ulises; Cortés Martínez, Atia; García Gasulla, Dario; Pérez Arnal, Raquel; Álvarez Napagao, Sergio; Álvarez Lacalle, Enrique (Springer Science and Business Media LLC, 2021-05-06)
    Article
    Restricted access - publisher's policy
    The COVID-19 pandemic has created an extraordinary medical, economic and humanitarian emergency. Artificial intelligence, in combination with other digital technologies, is being used as a tool to support the fight against ...

  • Negative-tension instability of scroll waves and Winfree turbulence in the Oregonator model 

    Alonso Muñoz, Sergio; Sagués Mestres, Francesc; Mikhailov, Alexander S (2006-10-06)
    Article
    Open Access
    Excitable media support self-organized scroll waves which can be unstable and give rise to three-dimensional wave chaos. Winfree turbulence of scroll waves results from the negative-tension instability of scroll waves; it ...

  • Wave pattern dynamics in fluctuating media 

    Sagués Mestres, Francesc; Alonso Muñoz, Sergio; Sancho Herrero, José María (2002-11-01)
    Article
    Open Access
    Analytical and numerical results on the ordering role of external random fluctuations in excitable systems are presented. Our study focuses on a simple model for excitable systems. Regular waves are created and sustained ...

  • Comparative analysis of geolocation information through mobile-devices under different COVID-19 mobility restriction patterns in Spain 

    Pérez Arnal, Raquel; Conesa Ortega, David; Álvarez Napagao, Sergio; Suzumura, Toyotaro; Català Sabaté, Martí; Álvarez Lacalle, Enrique; Garcia Gasulla, Dario (Multidisciplinary Digital Publishing Institute (MDPI), 2021-02-13)
    Article
    Open Access
    The COVID-19 pandemic is changing the world in unprecedented and unpredictable ways. Human mobility, being the greatest facilitator for the spread of the virus, is at the epicenter of this change. In order to study mobility ...

  • Empirical model for short-time prediction of COVID-19 spreading 

    Català Sabaté, Martí; Alonso Muñoz, Sergio; Álvarez Lacalle, Enrique; López Codina, Daniel; Cardona Iglesias, Pere Joan; Prats Soler, Clara (2020-12-09)
    Article
    Open Access
    The appearance and fast spreading of Covid-19 took the international community by surprise. Collaboration between researchers, public health workers, and politicians has been established to deal with the epidemic. One ...

  • Incidence and impact of COVID-19 in MS. A survey from a Barcelona MS Unit. 

    Sepúlveda, Maria; Llufriu, Sara; Martínez-Hernández, Eugenia; Català Sabaté, Martí; Artola, Montse; Hernando, Ana; Montejo, Carmen; Pulido-Valdeolivas, Irene; Martinez-Heras, Eloy; Guasp, Mar; Solana, Elisabeth; Llançó, Laura; Escudero, Domingo; Aldea, Marta; Prats Soler, Clara; Graus Ribas, Francesc; Blanco, Yolanda; Saiz, Albert (Lippincott Williams & Wilkins, 2021-01-27)
    Article
    Open Access
    Objective: To investigate the incidence of coronavirus disease 2019 (COVID-19) in a single-center cohort of patients with MS and to explore the contribution of their comorbidities and therapies to the outcome. Methods: ...

  • Modelización computacional cardiaca 

    Bragard, Jean; Camara Rey, Oscar; Echebarría Domínguez, Blas; Pueyo, Esther; Soudah Prieto, Eduardo; Vázquez, Mariano (Elsevier, 2020-08-01)
    Article
    Restricted access - publisher's policy
    Las enfermedades cardiovasculares tienen en la actualidad un gran impacto social y económico y constituyen una de las principales causas de mortalidad y morbilidad. Los modelos computacionales personalizados del corazón ...

  • Buffering and total calcium levels determine the presence of oscillatory regimes in cardiac cells 

    Marchena Angos, Miquel; Echebarría Domínguez, Blas; Shiferaw, Yohannes; Álvarez Lacalle, Enrique (2020-09-24)
    Article
    Open Access
    Calcium oscillations and waves induce depolarization in cardiac cells which are believed to cause life-threathening arrhythimas. In this work, we study the conditions for the appearance of calcium oscillations in both a ...

  • Origin of tuberculosis in the Paleolithic predicts unprecedented population growth and female resistance 

    Cardona Iglesias, Pere Joan; Català Sabaté, Martí; Prats Soler, Clara (Nature, 2020-01-08)
    Article
    Open Access
    Current data estimate the origin of Mycobacterium tuberculosis complex (MtbC) infection around 73,000 years before the common era (BCE), and its evolution to “modern” lineages around 46,000 BCE. Being MtbC a major killer ...

  • Effects of strain aging in NiTi SMA wire for dampers 

    Isalgué Buxeda, Antonio; Auguet Sangrá, Carlota E.; Torra Ferré, Vicenç; Carreras, Guillem; Lovey, Francisco Carlos (Elsevier, 2015)
    Article
    Open Access
    The thermo-mechanical properties of Shape Memory Alloys (SMA) as smart materials suggest their application as actuators, but also as dampers, thanks to the high damping properties during the hysteresis of the thermo-elastic ...

  • Modeling cell crawling strategies with a bistable model: from amoeboid to fan-shaped cell motion 

    Moreno Ramos, Eduardo; Flemming, Sven; Font Clos, Francesc; Holschneider, Matthias; Beta, Carsten; Alonso Muñoz, Sergio (2020-11-01)
    Article
    Restricted access - publisher's policy
    Eukaryotic cell motility involves a complex network of interactions between biochemical components and mechanical processes. The cell employs this network to polarize and induce shape changes that give rise to membrane ...

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