BIOCOM-SC - Grup de Biologia Computacional i Sistemes Complexos
El grup de recerca BIOCOM-SC aspira a crear sinergies de manera que els coneixements de física bàsica (fluids, materials, sistemes complexos) s’utilitzin per abordar problemes en biociència, des d’aquells d’interès en biomedicina (dinàmica d’ones elèctriques al cor, xarxes neuronals, tuberculosi) a d’altres d’enginyeria de sistemes biològics (simulació de sistemes microbians d’interès agroalimentari i medi ambiental). Per assolir aquest objectiu comptem amb un grup interdisciplinari on a més de físics hi ha matemàtics, enginyers i biòlegs, en col·laboració amb grups de biologia experimental de dins i fora de Catalunya. L’objectiu final és esdevenir un grup de referència en biologia teòrica i computacional capaç de fer el salt des de les idees de física fonamental a problemes d’interès biosanitari o mediambiental.
The group studies out-of-equilibrium systems by means of nonlinear dynamics techniques and their application to the self-organisation of complex systems, spatiotemporal pattern formation, biophysical systems, materials science, nanometric devices, studies and measurements in architectural and environmental acoustics and energetic efficiency in buildings.
The group studies out-of-equilibrium systems by means of nonlinear dynamics techniques and their application to the self-organisation of complex systems, spatiotemporal pattern formation, biophysical systems, materials science, nanometric devices, studies and measurements in architectural and environmental acoustics and energetic efficiency in buildings.
Col·leccions
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Altres [1]
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Articles de revista [58]
Enviaments recents
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Seedling emergence through soil surface seals under laboratory conditions: effect of mechanical impedance and seal moisture
(2017)
Article
Accés obertIt is well known that soil sealing strongly affects seedling emergence. The effect of soil sealing on the emergence of flax and turnip seedlings was studied in the laboratory. Seeds were sown in pots, watered, then covered ... -
How to deal with the modelling of epidemics? Some ideas and examples to be implemented in the classroom!
(2017)
Article
Accés restringit per política de l'editorialThe general objective of this work is to deal with different approaches for the representation of an epidemic considering the state of the individuals in the population, Susceptible, Infected or Recovered (SIR), which ... -
Ordering kinetics evaluation of FeAl powders
(2017-12-01)
Article
Accés obertIn this study, time resolved X-ray diffraction experiments using synchrotron X-ray radiation have been performed to get insight on the time and temperature dependent atomic ordering of an intermetallic Fe-40Al (at.%) ... -
Discretization-dependent model for weakly connected excitable media
(American Chemical Society (ACS), 2018-03-23)
Article
Accés obertPattern formation has been widely observed in extended chemical and biological processes. Although the biochemical systems are highly heterogeneous, homogenized continuum approaches formed by partial differential equations ... -
An automatic system for computing malaria parasite density in thin blood films
(Springer, 2018-01)
Capítol de llibre
Accés restringit per política de l'editorialMalaria is a major worldwide health problem, specially in countries with tropical climates and remote areas. In this paper, we present an automatic system for estimating malaria parasite density in thin blood smears. ... -
CD5L promotes M2 macrophage polarization through autophagy-mediated upregulation of ID3
(2018-03-12)
Article
Accés obertCD5L (CD5 molecule-like) is a secreted glycoprotein that controls key mechanisms in inflammatory responses, with involvement in processes such as infection, atherosclerosis, and cancer. In macrophages, CD5L promotes an ... -
Improving dating of three sites from Catalonia (NE Spain) via Archaeomagnetism
(2017-12-06)
Article
Accés obertArchaeomagnetic dating for four archaeological structures has been attempted in Catalonia (NE Spain) using magnetic inclination and declination values from three reference curves: the Iberian SVC and two curves computed ... -
Calcium alternans produced by increased sarcoplasmic reticulum refractoriness
(2011-09-29)
Article
Accés obertDespite the important role of electro-mechanical alternans in cardiac arrhythmogenesis, its molecular origin is not well understood. In this paper we want to study alternans that can be associated with alternations in the ... -
Calcium alternans is a global order-disorder phase transition: robustness on ryanodine receptor release dynamics
(2016-01-01)
Article
Accés obertElectromechanical alternans is a beat-to-beat alterna- tion in the strength of contraction of a cardiac cell which appears often due to an instability of calcium cycling. The global calcium signal in cardiomyocytes is ... -
Propagation malfunctions due to gap junction dysregulation
(2015-01-02)
Article
Accés obertGap junctions are membrane channels that connect the cytoplasm of adjacent cells allowing the cell-to-cell elec- trical coupling necessary for action potential propagation. Pathological conditions, such as malformations ... -
Effect of RyR2 refractoriness and hypercalcemia on calcium overload, spontaneous release, and calcium alternans
(2013)
Article
Accés restringit per política de l'editorialIn this work we use a computer model of a ventricular rabbit myocyte to study several factors that affect sarcoplasmic reticulum (SR) calcium load, such as hypercalcemia, SR calcium buffering, or ryanodine receptor ... -
Modeling tuberculosis transmission in urban cities through agent-based simulation: the case of Barcelona
(Association for Computing Machinery (ACM), 2017)
Comunicació de congrés
Accés obertTuberculosis remains one of the world’s deadliest infectious diseases. About one-third of the world’s population is infected with tuberculosis bacteria. Understanding the dynamics of transmission at different spatial ...
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