BIOCOM-SC - Grup de Biologia Computacional i Sistemes Complexos
El grup de recerca BIOCOM-SC aspira a crear sinergies de manera que els coneixements de física bàsica (fluids, materials, sistemes complexos) s’utilitzin per abordar problemes en biociència, des d’aquells d’interès en biomedicina (dinàmica d’ones elèctriques al cor, xarxes neuronals, tuberculosi) a d’altres d’enginyeria de sistemes biològics (simulació de sistemes microbians d’interès agroalimentari i medi ambiental). Per assolir aquest objectiu comptem amb un grup interdisciplinari on a més de físics hi ha matemàtics, enginyers i biòlegs, en col·laboració amb grups de biologia experimental de dins i fora de Catalunya. L’objectiu final és esdevenir un grup de referència en biologia teòrica i computacional capaç de fer el salt des de les idees de física fonamental a problemes d’interès biosanitari o mediambiental.
The group studies out-of-equilibrium systems by means of nonlinear dynamics techniques and their application to the self-organisation of complex systems, spatiotemporal pattern formation, biophysical systems, materials science, nanometric devices, studies and measurements in architectural and environmental acoustics and energetic efficiency in buildings.
The group studies out-of-equilibrium systems by means of nonlinear dynamics techniques and their application to the self-organisation of complex systems, spatiotemporal pattern formation, biophysical systems, materials science, nanometric devices, studies and measurements in architectural and environmental acoustics and energetic efficiency in buildings.
Col·leccions
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Altres [1]
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Articles de revista [73]
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Capítols de llibre [10]
Enviaments recents
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Editorial: The individual microbe: single-cell analysis and agent-based modelling
(2018-11-21)
Article
Accés obertThe field of microbial individual-based ecology, or µ IBE ( Kreft et al., 2013 ), is grounded in the notion that to truly understand the interactions of micr oorganisms with their biotic and abiotic environment, one ... -
Can systems immunology lead tuberculosis eradication?
(Elsevier, 2018-10-30)
Article
Accés obert25 years after the declaration of a Global Emergency by the World Health Organization, tuberculosis (TB) remains a major enemy to the humankind. During this period, much progress has been done to better understand its ... -
Ectopic beats arise from micro-reentries near infarct regions in simulations of a patient-specific heart model
(Nature, 2018-12-01)
Article
Accés obertEctopic beats are known to be involved in the initiation of a variety of cardiac arrhythmias. Although their location may vary, ectopic excitations have been found to originate from infarct areas, regions of micro-fibrosis ... -
Histidine decarboxylase-positive lactic acid bacteria strains and the formation of histamine in ripened cheeses
(2018-09-14)
Article
Accés obertThe relationship between histidine decarboxylase-positive (hdc+) lactic acid bacteria (LAB) counts and the amounts of biogenic amines, particularly histamine, in cheeses made with and without LAB starter were investigated. ... -
Killing many birds with two stones: hypoxia and fibrosis can generate ectopic beats in a human ventricular model
(2018-06-22)
Article
Accés obertDuring cardiac diseases many types of anatomical and functional remodeling of cardiac tissue can occur. In this work, we focus on two conditions: hypoxia and fibrosis, which are part of complex pathological modifications ... -
Development of a computational model of abscess formation
(2018-06-26)
Article
Accés obertIn some bacterial infections, the immune system cannot eliminate the invading pathogen. In these cases, the invading pathogen is successful in establishing a favorable environment to survive and persist in the host organism. ... -
Experimental study of a microchannel bubble injector for microgravity applications
(2009-01)
Article
Accés restringit per política de l'editorialWe perform a quantitative characterization of a microbubble injector in conditions relevant to microgravity. The injector pregenerates a slug flow by using a capillary T-junction, whose operation is robust to changes in ... -
Pattern forming instabilities of the nematic smectic-B interface
(2000-10)
Article
Accés restringit per política de l'editorialFree growth properties of the smectic B liquid crystalline phase into the supercooled nematic have been investigated in quasi-two-dimensional geometry. Different orientation combinations of the two phases have been achieved ... -
Heat diffusion anisotropy in dendritic growth: phase field simulations and experiments in liquid crystals
(1998-10)
Article
Accés restringit per política de l'editorialAn anisotropic heat diffusion coefficient is introduced in order to study some interfacial growth phenomena. This anisotropy has been incorporated in a phase field model which has been studied numerically to reproduce some ... -
Modeling random crawling, membrane deformation and intracellular polarity of motile amoeboid cells
(Public Library of Science (PLOS), 2018-08-01)
Article
Accés obertAmoeboid movement is one of the most widespread forms of cell motility that plays a key role in numerous biological contexts. While many aspects of this process are well investigated, the large cell-to-cell variability ... -
Bubble dynamics in turbulent duct flows: Lattice-Boltzmann simulations and drop tower experiments
(2018-06-23)
Article
Accés obertLattice-Boltzmann simulations of a turbulent duct flow have been carried out to obtain trajectories of passive tracers in the conditions of a series of microgravity experiments of turbulent bubble suspensions. The statistics ... -
Generation and control of monodisperse bubble suspensions in microgravity
(2018-06-01)
Article
Accés obertA new experimental setup for the generation of homogeneous, monodisperse bubble suspensions in turbulent duct flows in microgravity has been designed and tested in drop tower experiments. The setup provides independent ...
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