BIOCOM-SC - Grup de Biologia Computacional i Sistemes Complexos

 

El grup de recerca BIOCOM-SC aspira a crear sinergies de manera que els coneixements de física bàsica (fluids, materials, sistemes complexos) s’utilitzin per abordar problemes en biociència, des d’aquells d’interès en biomedicina (dinàmica d’ones elèctriques al cor, xarxes neuronals, tuberculosi) a d’altres d’enginyeria de sistemes biològics (simulació de sistemes microbians d’interès agroalimentari i medi ambiental). Per assolir aquest objectiu comptem amb un grup interdisciplinari on a més de físics hi ha matemàtics, enginyers i biòlegs, en col·laboració amb grups de biologia experimental de dins i fora de Catalunya. L’objectiu final és esdevenir un grup de referència en biologia teòrica i computacional capaç de fer el salt des de les idees de física fonamental a problemes d’interès biosanitari o mediambiental.

The group studies out-of-equilibrium systems by means of nonlinear dynamics techniques and their application to the self-organisation of complex systems, spatiotemporal pattern formation, biophysical systems, materials science, nanometric devices, studies and measurements in architectural and environmental acoustics and energetic efficiency in buildings.

The group studies out-of-equilibrium systems by means of nonlinear dynamics techniques and their application to the self-organisation of complex systems, spatiotemporal pattern formation, biophysical systems, materials science, nanometric devices, studies and measurements in architectural and environmental acoustics and energetic efficiency in buildings.

Recent Submissions

  • Nonlinearities due to refractoriness in SR Ca release 

    Peñaranda Ayllón, Angelina; Álvarez Lacalle, Enrique; Rodríguez Cantalapiedra, Inma; Echebarría Domínguez, Blas (Institute of Electrical and Electronics Engineers (IEEE), 2013-01-01)
    Conference lecture
    Open Access
    Calcium alternans is a pro-arrhytmic cardiac dysfunction related to beat-to-beat changes in the amplitude of intracellular calcium transient, that typically occurs at rapid pacing rates. Although oscillations in sarcoplasmic ...

  • Mecanismes que expliquen el manteniment de la TB en l'espècie humana 

    Cardona Iglesias, Pere Joan; Prats Soler, Clara (2019-03)
    Article
    Open Access

  • Unstable state decay in non-Markovian heat baths and weak signals detection 

    Jiménez Aquino, José Inés; Sánchez Salas, Norma; Ramírez de la Piscina Millán, Laureano; Romero Bastida, M. (2019-09-01)
    Article
    Open Access
    The statistics of the first passage and nonlinear relaxation times are used to characterize the decay process of an unstable state for an electrically charged Brownian particle embedded in non-Markovian heat baths under ...

  • Identification of yeast isolated from laboratory sourdoughs prepared with grape, apple, and yogurt 

    Gordún Quiles, Elena; Puig Pujol, Anna; Piñol, Lola; Carbó Moliner, Rosa (2018-02-01)
    Article
    Open Access
    Sourdough; Apple; Grap;, Yogurt; Molecular identification; Yeast

  • Effects of gravity level on bubble detachment, rise, and bouncing with a free surface 

    Suñol Galofre, Francesc Xavier; González Cinca, Ricardo (2019-02-05)
    Article
    Open Access
    Bubble detachment, rise, and bouncing upon impact with a free surface is studied experimentally in variable gravity conditions. Previous investigations focused on the effects of fluid properties such as ...

  • ESA/ELGRA Gravity-Related Research Summer School 

    González Cinca, Ricardo; Callens, Natacha; Carvil, Phil (2018)
    Conference report
    Open Access
    The European Low Gravity Research Association (ELGRA) and the European Space Agency (ESA) Education Office co -organi se at the ESA Academy’s Training and Learning Centre in ESA -ESEC, Belgium, ...

  • CD5L Drives M2 Polarization of Human Macrophages in Liver Cancer 

    Sanjurjo, Lucía; Aran, G.; Téllez, Érica; Silva-Martins, B.; López Codina, Daniel; Prats Soler, Clara; Armengol, C.; Sarrias, Maria Rosa (Wiley, 2018)
    Conference report
    Open Access

  • Stochastic coupled map model of subcellular calcium cycling in cardiac cells 

    Romero Castañeda, Luis; Álvarez Lacalle, Enrique; Shiferaw, Yohannes (Institute of Physics (IOP), 2019-02-01)
    Article
    Restricted access - publisher's policy
    In this study, we analyze a nonlinear map model of intracellular calcium (Ca) and voltage in cardiac cells. In this model, Ca release from the sarcoplasmic reticulum (SR) occurs at spatially distributed dyadic junctions ...

  • A General Equilibrium Model to Study Intracellular Calcium Homeostasis. New Insights on Ventricular Function 

    Álvarez Lacalle, Enrique; Conesa, David; Echebarría Domínguez, Blas; Shiferaw, Yohannes; Peñaranda Ayllón, Angelina; Rodríguez Cantalapiedra, Inma (2018)
    Conference report
    Open Access

  • Stability of oscillating hexagons in rotating convection 

    Echebarría Domínguez, Blas; Riecke, Hermann (2000)
    Article
    Open Access
    Breaking the chiral symmetry, rotation induces a secondary Hopf bifurcation in weakly nonlinear hexagon patterns which gives rise to oscillating hexagons. We study the stability of the oscillating hexagons using three ...

  • Sideband instabilities and defects of quasipatterns 

    Echebarría Domínguez, Blas; Riecke, Hermann (2001)
    Article
    Open Access
    Quasipatterns have been found in dissipative systems ranging from Faraday waves in vertically vibrated fluid layers to nonlinear optics. We describe the dynamics of octagonal, decagonal and dodecagonal quasipatterns by ...

  • Spatiotemporal control of cardiac alternans 

    Echebarría Domínguez, Blas; Karma, Alain (Institute of Physics (IOP), 2002)
    Article
    Restricted access - publisher's policy
    Electrical alternans are believed to be linked to the onset of life-threatening ventricular arrhythmias and sudden cardiac death. Recent studies have shown that alternans can be suppressed temporally by dynamic feedback ...

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