Articles de revista: Recent submissions

Now showing items 13-24 of 133

    • Action potential propagation: ion current or intramembrane electric field? 

      Martí Cabarrocas, Albert; Pérez González, Juan Jesús; Madrenas Boadas, Jordi (2018-01-22)
      Article
      Open Access
      The established action potential propagation mechanisms do not satisfactorily explain propagation on myelinated axons given the current knowledge of biological channels and membranes. The flow across ion channels presents ...

    • Effect of set up protocols on the accuracy of alchemical free energy calculation over a set of ACK1 inhibitors 

      Granadino, Jose Manuel; Mey, Antonia S. J. S.; Pérez González, Juan Jesús; Bosisio, Stefano; Rubio Martínez, Jaime; Michel, Julien (Public Library of Science (PLOS), 2019-03-01)
      Article
      Open Access
      Hit-to-lead virtual screening frequently relies on a cascade of computational methods that starts with rapid calculations applied to a large number of compounds and ends with more expensive computations restricted to a ...

    • Electrical evaluation of bacterial virulence factors using nanopores 

      Escosura Muñiz, Alfredo de la; Ivanova, Kristina Dimitrova; Tzanov, Tzanko (2019-03-19)
      Article
      Open Access
      In this work, we propose a novel methodology for electrical monitoring using nanoporous alumina membranes of virulence factors secreted by bacterial pathogens. Bacterial hyaluronidase (HYAL), which is produced by a number ...

    • Ligand binding mechanisms in human cone visual pigments 

      Srinivasan, Sundaramoorthy; Guixà González, Ramon; Cordomí, Arnau; Garriga Solé, Pere (2019-07)
      Article
      Open Access
      Vertebrate vision starts with light absorption by visual pigments in rod and cone photoreceptor cells of the retina. Rhodopsin, in rod cells, responds to dim light, whereas three types of cone opsins (red, green, and blue) ...

    • Multifunctional ZnO NPs-chitosan-gallic acid hybrid nanocoating to overcome contact lenses associated conditions and discomfort 

      Hoyo Pérez, Javier; Ivanova, Kristina Dimitrova; Guaus Guerrero, Ester; Tzanov, Tzanko (2019-02-13)
      Article
      Restricted access - publisher's policy
      Contact lenses (CL) provide visual correction but their use may also induce several adverse effects causative of discomfort and conditions that lead to stop or discontinue their use. Discomfort is mainly caused by insufficient ...

    • Molecular features characterizing non-peptide selectivity to the human B1 and B2 bradykinin receptors 

      Rasaeifar, B.; Lupala, C.S.; Gómez Gutierrez, Patricia; Pérez González, Juan Jesús (2019-01-01)
      Article
      Restricted access - publisher's policy
      Bradykinin is produced in response to inflammation, trauma, burns, shock, allergy and some cardiovascular diseases. Actions of this peptide are mediated through two different G-protein coupled receptors, named B1 and B2 ...

    • Physical states and thermodynamic properties of model Gram-negative bacterial inner membranes 

      Hoyo Pérez, Javier; Torrent Burgués, Juan; Tzanov, Tzanko (2018-12-06)
      Article
      Open Access
      Novel antimicrobial agents are focused to interact with the bacterial membrane whose lipid composition (number and position of unsaturations and lipid headgroup) is adapted according to environmental signals. The anticipation ...

    • Metal-enzyme nanoaggregates eradicate both gram-positive and gram-negative bacteria and their biofilms 

      Ferreres Cabanes, Guillem; Bassegoda Puigdomenech, Arnau; Hoyo Pérez, Javier; Torrent Burgués, Juan; Tzanov, Tzanko (2018-11-13)
      Article
      Open Access
      To palliate the appearance of antimicrobial resistance (AMR), the use of bactericidal agents acting differently than conventional antibiotics and the elimination of bacterial biofilm, are the two most promising strategies. ...

    • Smart sensing fabrics for live bacteria detection 

      Ferrer-Vilanova, Amparo; Ivanova, Kristina Dimitrova; Diaz-Gonzalez, Maria; Alonso, Yasmine; Guirado, Gonzalo; Tzanov, Tzanko; Muños-Berbel, Xavier (Multidisciplinary Digital Publishing Institute (MDPI), 2018-11-27)
      Article
      Open Access
      A smart textile for live bacteria detection of antimicrobial hospital tissues is here proposed. The capacity to detect viable bacteria is based on the use of Prussian Blue (PB) as electrochromic compound, with a clear ...

    • Enzymatic synthesis of a thiolated chitosan-based wound dressing crosslinked with chicoric acid 

      Stefanov, Ivaylo; Hinojosa Caballero, Dolores; Maspoch, Santiago; Hoyo Pérez, Javier; Tzanov, Tzanko (Royal Society of Chemistry (RSC), 2018-10-26)
      Article
      Open Access
      This work describes the enzymatic synthesis of multifunctional hydrogels for chronic wound treatment using thiolated chitosan and the natural polyphenol chicoric acid. Gelation was achieved by ...

    • New myeloperoxidase detection system based on enzyme-catalysed oxidative synthesis of a dye for paper-based diagnostic devices 

      Bassegoda Puigdomenech, Arnau; Ferreres Cabanes, Guillem; Pérez Rafael, Silvia; Hinojosa-Caballero, Dolores; Torrent Burgués, Juan; Tzanov, Tzanko (2018-10-21)
      Article
      Open Access
      The severity and cost of wound infections strongly demands for simple and fast methods for wound infection determination. Point-of-care testing devices play a crucial role in order to achieve a fast diagnosis and early ...

    • Thermodynamic behaviour of mixed films of an unsaturated and a saturated polar lipid : (Oleic Acid-Stearic Acid and POPC-DPPC) 

      Torrent Burgués, Juan (Multidisciplinary Digital Publishing Institute (MDPI), 2018-06)
      Article
      Open Access
      Mixed fatty acids or mixed phospholipids systems with saturated-unsaturated hydrocarbon chains are of biological interest. In this work, the monolayers of oleic acid-stearic acid (OA-SA) and palmitoyloleoylphosphatidylch ...