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Sono-enzymatically embedded antibacterial silver-lignin nanoparticles on cork filter material for water disinfection
(Multidisciplinary Digital Publishing Institute (MDPI), 2022-10-02)
Article
Open AccessProviding clean drinking water is a great challenge worldwide, especially for low-income countries where the access to safe water is limited. During the last decade, new biotechnological approaches have been explored to ... -
3D-printed polymer-infiltrated ceramic network with antibacterial biobased silver nanoparticles
(American Chemical Society, 2022-01-01)
Article
Restricted access - publisher's policyThis work aimed at the antimicrobial functionalization of 3D-printed polymer-infiltrated biomimetic ceramic networks (PICN). The antimicrobial properties of the polymer-ceramic composites were achieved by coating them with ... -
Rapid colorimetric detection of wound infection with a fluidic paper device
(Multidisciplinary Digital Publishing Institute (MDPI), 2022-08-15)
Article
Open AccessCurrent procedures for the assessment of chronic wound infection are time-consuming and require complex instruments and trained personnel. The incidence of chronic wounds worldwide, and the associated economic burden, urge ... -
Nano-formulation endows quorum quenching enzyme-antibiotic hybrids with improved antibacterial and antibiofilm activities against pseudomonas aeruginosa
(2022-07-11)
Article
Open AccessThe emergence of antibiotic resistant bacteria coupled with the shortage of efficient antibacterials is one of the most serious unresolved problems for modern medicine. In this study, the nano-hybridization of the clinically ... -
Antibacterial, antibiofilm, and antiviral farnesol-containing nanoparticles prevent Staphylococcus aureus from drug resistance development
(2022-07-07)
Article
Open AccessMultidrug antimicrobial resistance is a constantly growing health care issue associated with increased mortality and morbidity, and huge financial burden. Bacteria frequently form biofilm communities responsible for numerous ... -
Synthesis and evaluation of wound healing properties of hydro-diab hydrogel loaded with green-synthetized AGNPS: in vitro and in ex vivo studies
(Springer Nature, 2022-08)
Article
Open AccessIn diabetic patients, the presence of neuropathy, peripheral vascular diseases and ischemia, leads to the formation of foot ulcerations with a higher risk of infection because the normal response to bacterial infection is ... -
Electrical monitoring of infection biomarkers in chronic wounds using nanochannels
(2022-08-01)
Article
Open AccessChronic wounds represent an important healthcare challenge in developed countries, being wound infection a serious complication with significant impact on patients’ life conditions. However, there is a lack of methods ... -
Discovery of novel 2,3,5-trisubstituted pyridine analogs as potent inhibitors of IL-1ß via modulation of the p38 MAPK signaling pathway
(2021-11-05)
Article
Open AccessInterleukin-1ß is a central mediator of innate immune responses and inflammation. It plays a key role in a wide variety of pathologies, ranging from autoinflammatory diseases to metabolic syndrome and malignant tumors. It ... -
Effect of sodium valproate on the conformational stability of the visual G Protein-coupled receptor rhodopsin
(2021-05-19)
Article
Open AccessRhodopsin is the G protein-coupled receptor of rod photoreceptor cells that mediates vertebrate vision at low light intensities. Mutations in rhodopsin cause inherited retinal degenerative diseases such as retinitis ... -
Effects of cryoprotectants on phospholipid monolayers - concentration and species dependence
(2022-03)
Article
Open AccessThe effects of four cryoprotectants (dimethylformamide (DMF), ethylene glycol (EG), glycerol and dimethyl sulfoxide (DMSO)) on monolayers of four phospholipids were investigated at high cryoprotectant concentration (10% ... -
Fragment dissolved molecular dynamics: a systematic and efficient method to locate binding sites
(Royal Society of Chemistry (RSC), 2021)
Article
Open AccessDiverse computational methods to support Fragment-based drug discovery (FBDD) are available in the literature. Despite their demonstrated efficacy to support FBDD campaigns, they exhibit some drawbacks such as protein ... -
Discovery of diverse natural products as inhibitors of SARS-CoV-2 Mpro protease through virtual screening
(2021-11-22)
Article
Open AccessSARS-CoV-2 is a type of coronavirus responsible for the international outbreak of respiratory illness termed COVID-19 that forced the World Health Organization to declare a pandemic infectious disease situation of international ...
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