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Synthesis and evaluation of wound healing properties of hydro-diab hydrogel loaded with green-synthetized AGNPS: in vitro and in ex vivo studies
(Springer Nature, 2022-03-31)
Article
Open AccessIn diabetic patients, the presence of neuropathy, peripheral vascular diseases and ischemia, leads to the formation of foot ulcerations with a higher risk of infection because the normal response to bacterial infection is ... -
Electrical monitoring of infection biomarkers in chronic wounds using nanochannels
(2022-08-01)
Article
Open AccessChronic wounds represent an important healthcare challenge in developed countries, being wound infection a serious complication with significant impact on patients’ life conditions. However, there is a lack of methods ... -
Discovery of novel 2,3,5-trisubstituted pyridine analogs as potent inhibitors of IL-1ß via modulation of the p38 MAPK signaling pathway
(2021-11-05)
Article
Open AccessInterleukin-1ß is a central mediator of innate immune responses and inflammation. It plays a key role in a wide variety of pathologies, ranging from autoinflammatory diseases to metabolic syndrome and malignant tumors. It ... -
Effect of sodium valproate on the conformational stability of the visual G Protein-coupled receptor rhodopsin
(2021-05-19)
Article
Open AccessRhodopsin is the G protein-coupled receptor of rod photoreceptor cells that mediates vertebrate vision at low light intensities. Mutations in rhodopsin cause inherited retinal degenerative diseases such as retinitis ... -
Effects of cryoprotectants on phospholipid monolayers - concentration and species dependence
(2022-03)
Article
Open AccessThe effects of four cryoprotectants (dimethylformamide (DMF), ethylene glycol (EG), glycerol and dimethyl sulfoxide (DMSO)) on monolayers of four phospholipids were investigated at high cryoprotectant concentration (10% ... -
Fragment dissolved molecular dynamics: a systematic and efficient method to locate binding sites
(Royal Society of Chemistry (RSC), 2021)
Article
Open AccessDiverse computational methods to support Fragment-based drug discovery (FBDD) are available in the literature. Despite their demonstrated efficacy to support FBDD campaigns, they exhibit some drawbacks such as protein ... -
Discovery of diverse natural products as inhibitors of SARS-CoV-2 Mpro protease through virtual screening
(2021-11-22)
Article
Restricted access - publisher's policySARS-CoV-2 is a type of coronavirus responsible for the international outbreak of respiratory illness termed COVID-19 that forced the World Health Organization to declare a pandemic infectious disease situation of international ... -
Characterization of modified solid electrodes with organized thin films of a tetra-substituted zinc phthalocyanine
(2022-04-01)
Article
Open AccessOrganized thin films of a zinc phthalocyanine have been deposited on solid electrodes using several techniques, such as drop casting, immersion and Langmuir-Blodgett (LB), at several conditions, and their electrochemical ... -
Lysozyme influence on monolayers of individual and mixed lipids
(Multidisciplinary Digital Publishing Institute (MDPI), 2022-03)
Article
Open AccessFatty acids, cholesterol, and phospholipids are amphiphilic compounds of biological interest, which form ordered monolayers mimicking biomembranes, and can be studied with the Langmuir technique using surface pressure-area ... -
Electrochemical quantification of biomarker myeloperoxidase
(2022-02-22)
Article
Restricted access - publisher's policyPoint of care testing (PoCT) devices permit precise and rapid detection of disease-related biomarkers contributing to an early disease diagnosis and administration of an appropriate treatment. The enzyme myeloperoxidase ... -
Hyaluronic acid derivative molecular weight-dependent synthesis and antimicrobial effect of hybrid silver nanoparticles
(2021-12-14)
Article
Open AccessSilver nanoparticles (Ag NPs) appeared as promising antimicrobial candidates to face the development of antibiotic resistance. Although reported as toxic towards mammalian cells, their combination with biomolecules have ... -
Simultaneous ultrasound-assisted hybrid polyzwitterion/antimicrobial peptide nanoparticles synthesis and deposition on silicone urinary catheters for prevention of biofilm-associated infections
(2021-11-21)
Article
Open AccessNosocomial infections caused by antibiotic-resistant bacteria are constantly growing healthcare threats, as they are the reason for the increased mortality, morbidity, and considerable financial burden due to the poor ...
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