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Poly(sulfobetaine methacrylate)/poly(ethylene glycole) hydrogels for chronic wounds management
(Elsevier, 2019-05-14)
Article
Restricted access - publisher's policyPolyzwitterions (PZI) recently emerged as biomaterials with excellent bio- and haemo-compatibility, demonstrating lower protein adsorption on their surfaces even compared to the golden standard in the field – poly(ethylene ... -
Action potential propagation: ion current or intramembrane electric field?
(2018-01-22)
Article
Open AccessThe established action potential propagation mechanisms do not satisfactorily explain propagation on myelinated axons given the current knowledge of biological channels and membranes. The flow across ion channels presents ... -
Effect of set up protocols on the accuracy of alchemical free energy calculation over a set of ACK1 inhibitors
(Public Library of Science (PLOS), 2019-03-01)
Article
Open AccessHit-to-lead virtual screening frequently relies on a cascade of computational methods that starts with rapid calculations applied to a large number of compounds and ends with more expensive computations restricted to a ... -
Electrical evaluation of bacterial virulence factors using nanopores
(2019-03-19)
Article
Restricted access - publisher's policyIn this work, we propose a novel methodology for electrical monitoring using nanoporous alumina membranes of virulence factors secreted by bacterial pathogens. Bacterial hyaluronidase (HYAL), which is produced by a number ... -
Ligand binding mechanisms in human cone visual pigments
(2019-07)
Article
Restricted access - publisher's policyVertebrate vision starts with light absorption by visual pigments in rod and cone photoreceptor cells of the retina. Rhodopsin, in rod cells, responds to dim light, whereas three types of cone opsins (red, green, and blue) ... -
Multifunctional ZnO NPs-chitosan-gallic acid hybrid nanocoating to overcome contact lenses associated conditions and discomfort
(2019-02-13)
Article
Restricted access - publisher's policyContact lenses (CL) provide visual correction but their use may also induce several adverse effects causative of discomfort and conditions that lead to stop or discontinue their use. Discomfort is mainly caused by insufficient ... -
Molecular features characterizing non-peptide selectivity to the human B1 and B2 bradykinin receptors
(2019-01-01)
Article
Restricted access - publisher's policyBradykinin is produced in response to inflammation, trauma, burns, shock, allergy and some cardiovascular diseases. Actions of this peptide are mediated through two different G-protein coupled receptors, named B1 and B2 ... -
Physical states and thermodynamic properties of model Gram-negative bacterial inner membranes
(2018-12-06)
Article
Restricted access - publisher's policyNovel antimicrobial agents are focused to interact with the bacterial membrane whose lipid composition (number and position of unsaturations and lipid headgroup) is adapted according to environmental signals. The anticipation ... -
Metal-enzyme nanoaggregates eradicate both gram-positive and gram-negative bacteria and their biofilms
(2018-11-13)
Article
Restricted access - publisher's policyTo palliate the appearance of antimicrobial resistance (AMR), the use of bactericidal agents acting differently than conventional antibiotics and the elimination of bacterial biofilm, are the two most promising strategies. ... -
Smart sensing fabrics for live bacteria detection
(Multidisciplinary Digital Publishing Institute (MDPI), 2018-11-27)
Article
Open AccessA smart textile for live bacteria detection of antimicrobial hospital tissues is here proposed. The capacity to detect viable bacteria is based on the use of Prussian Blue (PB) as electrochromic compound, with a clear ... -
Enzymatic synthesis of a thiolated chitosan-based wound dressing crosslinked with chicoric acid
(Royal Society of Chemistry (RSC), 2018-10-26)
Article
Open AccessThis work describes the enzymatic synthesis of multifunctional hydrogels for chronic wound treatment using thiolated chitosan and the natural polyphenol chicoric acid. Gelation was achieved by ... -
New myeloperoxidase detection system based on enzyme-catalysed oxidative synthesis of a dye for paper-based diagnostic devices
(2018-10-21)
Article
Restricted access - publisher's policyThe severity and cost of wound infections strongly demands for simple and fast methods for wound infection determination. Point-of-care testing devices play a crucial role in order to achieve a fast diagnosis and early ...
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