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Antimicrobial and antifouling hyaluronic acid-cobalt nanogel coatings built sonochemically on contact lenses
(2024-12)
Article
Open AccessThe wearing of contact lenses (CLs) may cause bacterial infections, leading in turn to more serious complications and ultimately vision impairment. In this scenario, the first step is the adhesion of tear proteins, which ... -
Theranostic nano-enabled polyurethane eso-sponges coupled to surface enhanced Raman scattering for detection and control of bacteria killing
(2024-08-08)
Article
Open AccessHerein, a facile approach toward converting a three-dimensional polyurethane sponge (PUS), employed in endoluminal vacuum-assisted closure (endo-VAC) therapies, in a theranostic material able to detect and to inhibit ... -
193 effect of template selection on the construction of atomistic models of GPCRs by homology modeling
(2015-05-18)
Article
Open AccessAnalysis of the diverse crystallographic structures of G-Protein Coupled Receptors (GPCRs) available suggests that although they share a common seven helix bundle, there are specific features that might be relevant for ... -
Unveiling the potential of CuO and Cu2O nanoparticles against novel copper-resistant pseudomonas strains: an in-depth comparison
(2024-10-13)
Article
Open AccessFour novel Pseudomonas strains with record resistance to copper (Cu2+) previously isolated from ecologically diverse samples (P. lactis UKR1, P. panacis UKR2, P. veronii UKR3, and P. veronii UKR4) were tested against ... -
Biofilm prevention and removal in non-target pseudomonas strain by siphovirus-like coliphage
(2024-10-09)
Article
Open AccessBackground/Objectives. Bacteriophages have gained significant interest as a potential solution to combat harmful bacteria, especially in the fight against antimicrobial resistance. With the rise in drug-resistant microorganisms, ... -
Integrated biofilm dispersion and virulence responsiveness for targeted treatment of pseudomonas aeruginosa infection in lungs
(2024-11-12)
Article
Open AccessThe self-organization of microbes into biofilms provides multiple benefits including tolerance to mechanical stress and resistance to immune defences and antibiotics. Coupled to a compromised mucociliary function, these ... -
Retigabine increases the conformational stability of the visual photoreceptor rhodopsin
(2024-09)
Article
Open AccessRhodopsin is the key photoreceptor protein that mediates vision in low-light conditions. Mutations in rhodopsin are the cause of retinal degenerative diseases such as retinitis pigmentosa. Some of these mutations cause a ... -
Enzymatically built nanoenabled antimicrobial coating on urinary catheters
(2024-07-23)
Article
Open AccessCatheter-associated urinary tract infections represent a major share of nosocomial infections, and are associated with longer periods of hospitalization and a huge financial burden. Currently, there are only a handful of ... -
Poly(vinyl chloride) films incorporated with antioxidant ZnO-flavonoid nanoparticles: a strategy for food preservation
(Multidisciplinary Digital Publishing Institute (MDPI), 2024-08-29)
Article
Open AccessAntioxidant films were prepared using poly(vinyl chloride) (PVC) incorporated with 0.5% or 1.0% zinc oxide (ZnO)-flavonoid (quercetin or morin) nanoparticles (NPZnO-Q% or NPZnO-M%) via the casting method. NP incorporation ... -
Multifunctional piezoelectric surfaces enhanced with layer-by-layer coating for improved osseointegration and antibacterial performance
(Elsevier, 2024-11)
Article
Open AccessImplant failure is primarily caused by poor osseointegration and bacterial colonization, which demands readmissions and revision surgeries to correct it. A novel approach involves engineering multifunctional interfaces ... -
Shedding light on dark chemical matter: the discovery of a SARS-CoV-2 Mpro main protease inhibitor through Intensive virtual screening and in vitro evaluation
(Multidisciplinary Digital Publishing Institute (MDPI), 2024-06-01)
Article
Open AccessThe development of specific antiviral therapies targeting SARS-CoV-2 remains fundamental because of the continued high incidence of COVID-19 and limited accessibility to antivirals in some countries. In this context, dark ... -
Exploring the effects of lignin nanoparticles in different zebrafish inflammatory models
(2024-07-30)
Article
Open AccessPurpose: Lignin is the most abundant source of aromatic biopolymers and has gained interest in industrial and biomedical applications due to the reported biocompatibility and defense provided against bacterial and fungal ...
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