Now showing items 1-12 of 164

    • Polyphenols and visual health: potential effects on degenerative retinal diseases 

      Fernandez Gonzalez, Pol; Mas Sanchez, Aina; Garriga Solé, Pere (2021-06-04)
      Article
      Open Access
      Dietary polyphenols are a group of natural compounds that have been proposed to have beneficial effects on human health. They were first known for their antioxidant properties, but several studies over the years have shown ...
    • Lipid artificial tears at a mimetic ocular interface 

      Torrent Burgués, Juan; Hoyo Pérez, Javier; Tzanov, Tzanko (2021-08)
      Article
      Open Access
      We studied the behaviour of three lipid tear products, commercialised by the same brand, as Langmuir films at the air/liquid interface to simulate the ocular environment. No significant differences were observed in the ...
    • Hybrid tellurium-lignin nanoparticles with enhanced antibacterial properties 

      Morena Gatius, Ángela Gala; Bassegoda Puigdomenech, Arnau; Hoyo Pérez, Javier; Tzanov, Tzanko (2021-04-07)
      Article
      Restricted access - publisher's policy
      The surge of antibiotic-resistant bacteria is leading to the loss of antibiotic treatment effectiveness, resulting in prolonged infections and even death. Against this healthcare threat, antimicrobial nanoparticles that ...
    • New insights into the stereochemical requirements of the bombesin BB1 receptor antagonists binding 

      Rasaeifar, Bahareh; Gómez Gutiérrez, Patricia; Pérez González, Juan Jesús (2020-08-17)
      Article
      Open Access
      Members of the family of bombesinlike peptides exert a wide range of biological activities both at the central nervous system and in peripheral tissues through at least three G-Protein Coupled Receptors: BB1, BB2 and BB3. ...
    • Discovery of a bradykinin b2 partial agonist profile of raloxifene in a drug repurposing campaign 

      Gómez Gutiérrez, Patricia; Pérez González, Juan Jesús (2020-12-29)
      Article
      Open Access
      Covid-19 urges a deeper understanding of the underlying molecular mechanisms involved in illness progression to provide a prompt therapeutical response with an adequate use of available drugs, including drug repurposing. ...
    • Anti-inflammatory effect of amygdalin analogs following topical administration on the TPA-induced irritant contact dermatitis model in mice 

      Pérez González, Juan Jesús (2021-01-26)
      Article
      Open Access
      Amygdalin is a cyanogenic glycoside found in seeds of apricots, peaches, almonds, and other rosaceous stone fruits. A few years ago, amygdalin was identified as a peptidomimetic of peptide T, a compound that had been ...
    • Interactions of cryoprotective agents with phospholipid membranes - A Langmuir monolayer study 

      Raju, Rekha; Torrent Burgués, Juan; Bryant, Gary (2020-09)
      Article
      Open Access
      The influence of four common cryoprotectants (dimethyl sulfoxide, glycerol, ethylene glycol and dimethylformamide) on monolayers of four common phospholipids (DPPC, DOPC, POPC and POPE) have been studied using Langmuir ...
    • Antimicrobial lightweight materials and components 

      Morena Gatius, Ángela Gala; Ferreres Cabanes, Guillem; Ivanova, Kristina Dimitrova; Pérez Rafael, Silvia; Tzanov, Tzanko (Elsevier, 2020-12-02)
      Part of book or chapter of book
      Restricted access - publisher's policy
      Lightweight materials and components have gained remarkable scientific and technological importance in the recent times as the main drivers of innovation. They are finding widespread use across all industry sectors to ...
    • Molecular features of non-selective small molecule antagonists of the Bradykinin receptors 

      Rasaeifar, Bahareh; Gómez Gutierrez, Patricia; Pérez González, Juan Jesús (2020-09-21)
      Article
      Open Access
      Angiotensin converting enzyme 2 (ACE2) downregulation is a key negative factor for the severity of lung edema and acute lung failure observed in patients infected with SARS-CoV-2. ACE2 downregulation affects the levels of ...
    • Structural study of a retro-enantiomer peptide with possible application in the pre-exposure prophylaxis of HIV infection 

      Gómara Elena, María José; Pérez, Yolanda; Gómez Gutierrez, Patricia; Pérez González, Juan Jesús (Nature, 2020-09-02)
      Article
      Open Access
      Based on the structure of an HIV-1 entry inhibitor peptide two stapled- and a retro-enantio peptides have been designed to provide novel prevention interventions against HIV transmission. The three peptides show greater ...
    • Sonochemical coating of Prussian Blue for the production of smart bacterial-sensing hospital textiles 

      Ferrer Vilanova, Amparo; Alonso, Yasmine; Dietvorst, Jiri; Pérez-Montero, Marta; Rodríguez-Rodríguez, Rosalía; Ivanova, Kristina Dimitrova; Tzanov, Tzanko; Vigués, Núria; Mas, Jordi; Guirado, Gonzalo; Muñoz-Berbel, Xavier (2020-08-27)
      Article
      Restricted access - publisher's policy
      In healthcare facilities, environmental microbes are responsible for numerous infections leading to patient’s health complications and even death. The detection of the pathogens present on contaminated surfaces is crucial, ...
    • Antibody-enabled antimicrobial nanocapsules for selective elimination of Staphylococcus aureus 

      Ivanova, Kristina Dimitrova; Asenova Ivanova, Aleksandra; Ramon Portés, Eva; Hoyo Pérez, Javier; Sanchez-Gomez, Susana; Tzanov, Tzanko (2020-07-16)
      Article
      Open Access
      Targeted bactericide nanosystems hold significant promise to improve the efficacy of existing antimicrobials for treatment of severe bacterial infections, minimizing the side effects and lowering the risk of antibiotic ...