El grup de recerca treballa en el camp de l'estructura-funció de proteïnes d'interès biomèdic i biotecnològic. Es porta a terme el disseny i l?obtenció de proteïnes recombinants mitjançant tècniques d'enginyeria genètica. Aquestes proteïnes són purificades i caracteritzades per tècniques bioquímiques i espectroscòpiques. També es treballa en la modificació d'enzims per a aplicacions en processos biotecnològics d'interès industrial.

http://futur.upc.edu/GBMI

The research group works on the structure and function of proteins of biomedical and biotechnological relevance. Recombinant proteins are designed and obtained by means of genetic engineering techniques. These proteins are purified and characterised using biochemical and spectroscopic methods. Enzyme engineering and modification are also studied, for their application to biotechnological processes in industry.

http://futur.upc.edu/GBMI

The research group works on the structure and function of proteins of biomedical and biotechnological relevance. Recombinant proteins are designed and obtained by means of genetic engineering techniques. These proteins are purified and characterised using biochemical and spectroscopic methods. Enzyme engineering and modification are also studied, for their application to biotechnological processes in industry.

http://futur.upc.edu/GBMI

Recent Submissions

  • Durable antimicrobial cotton textiles coated sonochemically with ZnO nanoparticles embedded in an in-situ enzymatically generated bioadhesive 

    Salat, Marc; Petkova, Petya; Hoyo Pérez, Javier; Perelshtein, Ilana; Gedanken, Aharon; Tzanov, Tzanko (2018-02-14)
    Article
    Restricted access - publisher's policy
    An important preventive measure for providing a bacteria-free environment for the patients is the introduction of highly efficient and durable antibacterial textiles in hospitals. This work describes a single step ...
  • Tuning ubiquinone position in biomimetic monolayer membranes 

    Hoyo Pérez, Javier; Guaus Guerrero, Ester; Torrent Burgués, Juan (2017-06-19)
    Article
    Restricted access - publisher's policy
    Artificial lipid bilayers have been extensively studied as models that mimic natural membranes (biomimetic membranes). Several attempts of biomimetic membranes inserting ubiquinone (UQ) have been performed to enlighten ...
  • Strategies to prevent the occurrence of resistance against antibiotics by using advanced materials 

    Bassegoda Puigdomenech, Arnau; Ivanova, Kristina Dimitrova; Ramon, Eva; Tzanov, Tzanko (2018-02-01)
    Article
    Restricted access - publisher's policy
    Drug resistance occurrence is a global healthcare concern responsible for the increased morbidity and mortality in hospitals, time of hospitalisation and huge financial loss. The failure of the most antibiotics to kill ...
  • Layer-by-layer decorated nanoparticles with tunable antibacterial and antibiofilm properties against both gram-positive and gram-negative bacteria 

    Asenova Ivanova, Aleksandra; Ivanova, Kristina Dimitrova; Hoyo Pérez, Javier; Sanchez-Gomez, Susana; Heinze, Thomas; Tzanov, Tzanko (2018-01-09)
    Article
    Restricted access - publisher's policy
    acteria-mediated diseases are a global healthcare concern due to the development and spread of antibiotic resistant strains. Cationic compounds are considered membrane active biocidal agents having a great potential to ...
  • Identification of potential small molecule binding pockets in p38a MAP kinase 

    Gómez Gutierrez, Patricia; Rubio Martínez, Jaime; Pérez González, Juan Jesús (2017-10-23)
    Article
    Open Access
    Given the essential role played by protein kinases in regulating cellular pathways, their dysregulation can result in the onset and/or progression of various human diseases. Structural analysis of diverse protein kinases ...
  • Social responsibility as a transversal competence of graduates 

    Pérez González, Juan Jesús (2016)
    Conference report
    Open Access
    Paper purpose: The aim of the present communication is to propose a procedure to assess the level of competence achieved by graduates. Design/methodology/theoretical approach: We propose to use a quality assurance ...
  • Effect of the solvent on the conformational behavior of the alanine dipeptide deduced from MD simulations 

    Rubio Martínez, Jaime; Tomás Belenguer, María Santos; Pérez González, Juan Jesús (2017-11-01)
    Article
    Open Access
    In general, peptides do not exhibit a well-defined conformational profile in solution. However, despite the experimental blurred picture associated with their structure, compelling spectroscopic evidence shows that peptides ...
  • Antibacterial coatings on medical devices 

    Ivanova, Kristina Dimitrova; Bassegoda Puigdomenech, Arnau; Tzanov, Tzanko (Elsevier, 2017-11-02)
    Part of book or chapter of book
    Restricted access - publisher's policy
  • Hydrogel dressings for advanced wound management 

    Francesko, Antonio; Petkova, Petya; Tzanov, Tzanko (2017-09-20)
    Article
    Restricted access - publisher's policy
    Composed in a large extent of water and due to their non-adhesiveness, hydrogels found their way to the wound dressing market as materials that provide a moisture environment for healing while being comfortable to the ...
  • Studies on lipid artificial tears 

    Torrent Burgués, Juan (2017-09-12)
    External research report
    Open Access
    The use of artificial tears is related with dry eye problems or ocular irritations. It exist different types of artificial tears. One type of them is the lipid artificial tears which tray to repair or improve the lipid ...
  • Using molecular dynamics for the refinement of atomistic models of GPCRs by homology modeling 

    Lupala, Cecylia Severin; Rasaeifar, Bahareh; Gómez Gutiérrez, Patricia; Pérez González, Juan Jesús (2017-08-13)
    Article
    Restricted access - publisher's policy
    Despite GPCRs sharing a common seven helix bundle, analysis of the diverse crystallographic structures available reveal specific features that might be relevant for ligand design. Despite the number of crystallographic ...
  • Flavonoid allosteric modulation of mutated visual rhodopsin associated with retinitis pigmentosa 

    Herrera Hernández, María Guadalupe; Ramon Portés, Eva; Lupala, Cecylia Severin; Tena Campos, Mercè; Pérez González, Juan Jesús; Garriga Solé, Pere (Macmillan Publishers, 2017-12-01)
    Article
    Open Access
    Dietary flavonoids exhibit many biologically-relevant functions and can potentially have beneficial effects in the treatment of pathological conditions. In spite of its well known antioxidant properties, scarce structural ...

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