El grup de recerca treballa en el camp de l'estructura-funció de proteïnes d'interès biomèdic i biotecnològic. Es porta a terme el disseny i l?obtenció de proteïnes recombinants mitjançant tècniques d'enginyeria genètica. Aquestes proteïnes són purificades i caracteritzades per tècniques bioquímiques i espectroscòpiques. També es treballa en la modificació d'enzims per a aplicacions en processos biotecnològics d'interès industrial.

http://futur.upc.edu/GBMI

The research group works on the structure and function of proteins of biomedical and biotechnological relevance. Recombinant proteins are designed and obtained by means of genetic engineering techniques. These proteins are purified and characterised using biochemical and spectroscopic methods. Enzyme engineering and modification are also studied, for their application to biotechnological processes in industry.

http://futur.upc.edu/GBMI

The research group works on the structure and function of proteins of biomedical and biotechnological relevance. Recombinant proteins are designed and obtained by means of genetic engineering techniques. These proteins are purified and characterised using biochemical and spectroscopic methods. Enzyme engineering and modification are also studied, for their application to biotechnological processes in industry.

http://futur.upc.edu/GBMI

Enviaments recents

  • Inhibition of quorum-sensing: A new paradigm in controlling bacterial virulence and biofilm formation 

    Asenova Ivanova, Aleksandra; Ivanova, Kristina Dimitrova; Tzanov, Tzanko (Springer Nature, 2018-05-31)
    Capítol de llibre
    Accés restringit per política de l'editorial
    Bacterial pathogens coordinate the expression of multiple virulence factors and formation of biofilms in cell density dependent manner, through a phenomenon named quorum sensing (QS). Protected in the biofilm community, ...
  • Thermodynamic behaviour of mixed films of an unsaturated and a saturated polar lipid : (Oleic Acid-Stearic Acid and POPC-DPPC) 

    Torrent Burgués, Juan (Multidisciplinary Digital Publishing Institute (MDPI), 2018-06)
    Article
    Accés obert
    Mixed fatty acids or mixed phospholipids systems with saturated-unsaturated hydrocarbon chains are of biological interest. In this work, the monolayers of oleic acid-stearic acid (OA-SA) and palmitoyloleoylphosphatidylch ...
  • Bottom-up layer-by-layer assembling of antibacterial freestanding nanobiocomposite films 

    Francesko, Antonio; Ivanova, Kristina Dimitrova; Hoyo Pérez, Javier; Pérez-Rafael, Silvia; Petkova, Petya; Fernandes Macedo, Margarida Maria; Heinze, Thomas; Mendoza Gómez, Ernesto; Tzanov, Tzanko (2018-07-27)
    Article
    Accés restringit per política de l'editorial
    In this study, freestanding nanobiocomposite films were obtained by the sequential deposition of biopolymer-capped silver nanoparticles (AgNPs) and hyaluronic acid (HA). At first, dispersions ofAgNPs decorated with chitosan ...
  • The Langmuir technique applied to the study of natural tears 

    Guaus Guerrero, Ester; Torrent Burgués, Juan (Springer, 2018-06-01)
    Article
    Accés restringit per política de l'editorial
    As a new proposal, natural tears collected from the Schirmer strips were studied using surface pressure-area, p-A, isotherms obtained with the Langmuir technique. Parameters such as limit surface pressure, plimit, elastic ...
  • Thylakoid membrane bioenergetics 

    Guaus Guerrero, Ester; Torrent Burgués, Juan; Hoyo Pérez, Javier (Elsevier, 2018-04-23)
    Capítol de llibre
    Accés restringit per política de l'editorial
    Oxygenic photosynthesis is a unique and essential photochemical process in which solar energy is used to oxidize water and to form carbohydrates. In this process molecular oxygen is released as a by-product. Thylakoid ...
  • Designing Peptidomimetics 

    Pérez González, Juan Jesús (2018-07-02)
    Article
    Accés restringit per política de l'editorial
    The concept of a peptidomimetic was coined about forty years ago. Since then, an enormous effort and interest has been devoted to mimic the properties of peptides with small molecules or pseudopeptides. The present report ...
  • Blockade of the Interaction of Calcineurin with FOXO in Astrocytes Protects Against Amyloid-beta-Induced Neuronal Death 

    Fernandez, Ana M.; Hervas, Ruben; Dominguez Fraile, Manuel; Garrido Victoria, Navarro; Gómez Gutiérrez, Patricia; Vega, Miguel; Vitorica, Javier; Pérez González, Juan Jesús; Torres Aleman, Ignacio (2016-01-01)
    Article
    Accés obert
    Astrocytes actively participate in neuro-inflammatory processes associated to Alzheimer's disease (AD), and other brain pathologies. We recently showed that an astrocyte-specific intracellular signaling pathway involving ...
  • Human blue cone opsin regeneration involves secondary retinal binding with analog specificity 

    Srinivasan, Sundaramoorthy; Fernández Sampedro, Miguel Ángel; Morillo Cazorla, Margarita; Ramon Portés, Eva; Jiménez Rosés, Mireia; Cordomi, Arnau; Garriga Solé, Pere (2018-03-27)
    Article
    Accés restringit per política de l'editorial
    Human color vision is mediated by the red, green, and blue cone visual pigments. Cone opsins are G-protein-coupled receptors consisting of an opsin apoprotein covalently linked to the 11-cis-retinal chromophore. All visual ...
  • Report on mixed monolayer films of a saturated and an unsaturated polar lipid 

    Torrent Burgués, Juan (2018-05-14)
    Report de recerca
    Accés obert
  • Durable antimicrobial cotton textiles coated sonochemically with ZnO nanoparticles embedded in an in-situ enzymatically generated bioadhesive 

    Salat, Marc; Petkova, Petya; Hoyo Pérez, Javier; Perelshtein, Ilana; Gedanken, Aharon; Tzanov, Tzanko (2018-02-14)
    Article
    Accés restringit per política de l'editorial
    An important preventive measure for providing a bacteria-free environment for the patients is the introduction of highly efficient and durable antibacterial textiles in hospitals. This work describes a single step ...
  • Tuning ubiquinone position in biomimetic monolayer membranes 

    Hoyo Pérez, Javier; Guaus Guerrero, Ester; Torrent Burgués, Juan (2017-06-19)
    Article
    Accés obert
    Artificial lipid bilayers have been extensively studied as models that mimic natural membranes (biomimetic membranes). Several attempts of biomimetic membranes inserting ubiquinone (UQ) have been performed to enlighten ...
  • Strategies to prevent the occurrence of resistance against antibiotics by using advanced materials 

    Bassegoda Puigdomenech, Arnau; Ivanova, Kristina Dimitrova; Ramon, Eva; Tzanov, Tzanko (2018-02-01)
    Article
    Accés restringit per política de l'editorial
    Drug resistance occurrence is a global healthcare concern responsible for the increased morbidity and mortality in hospitals, time of hospitalisation and huge financial loss. The failure of the most antibiotics to kill ...

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