El grup de recerca treballa en el camp de l'estructura-funció de proteïnes d'interès biomèdic i biotecnològic. Es porta a terme el disseny i l?obtenció de proteïnes recombinants mitjançant tècniques d'enginyeria genètica. Aquestes proteïnes són purificades i caracteritzades per tècniques bioquímiques i espectroscòpiques. També es treballa en la modificació d'enzims per a aplicacions en processos biotecnològics d'interès industrial.

http://futur.upc.edu/GBMI

The research group works on the structure and function of proteins of biomedical and biotechnological relevance. Recombinant proteins are designed and obtained by means of genetic engineering techniques. These proteins are purified and characterised using biochemical and spectroscopic methods. Enzyme engineering and modification are also studied, for their application to biotechnological processes in industry.

http://futur.upc.edu/GBMI

The research group works on the structure and function of proteins of biomedical and biotechnological relevance. Recombinant proteins are designed and obtained by means of genetic engineering techniques. These proteins are purified and characterised using biochemical and spectroscopic methods. Enzyme engineering and modification are also studied, for their application to biotechnological processes in industry.

http://futur.upc.edu/GBMI

Enviaments recents

  • Molecular features characterizing non-peptide selectivity to the human B1 and B2 bradykinin receptors 

    Rasaeifar, B.; Lupala, C.S.; Gómez Gutierrez, Patricia; Pérez González, Juan Jesús (2019-01-01)
    Article
    Accés restringit per política de l'editorial
    Bradykinin is produced in response to inflammation, trauma, burns, shock, allergy and some cardiovascular diseases. Actions of this peptide are mediated through two different G-protein coupled receptors, named B1 and B2 ...
  • Physical states and thermodynamic properties of model Gram-negative bacterial inner membranes 

    Hoyo Pérez, Javier; Torrent Burgués, Juan; Tzanov, Tzanko (2018-12-06)
    Article
    Accés restringit per política de l'editorial
    Novel antimicrobial agents are focused to interact with the bacterial membrane whose lipid composition (number and position of unsaturations and lipid headgroup) is adapted according to environmental signals. The anticipation ...
  • Metal-enzyme nanoaggregates eradicate both gram-positive and gram-negative bacteria and their biofilms 

    Ferreres Cabanes, Guillem; Bassegoda Puigdomenech, Arnau; Hoyo Pérez, Javier; Torrent Burgués, Juan; Tzanov, Tzanko (2018-11-13)
    Article
    Accés restringit per política de l'editorial
    To palliate the appearance of antimicrobial resistance (AMR), the use of bactericidal agents acting differently than conventional antibiotics and the elimination of bacterial biofilm, are the two most promising strategies. ...
  • Smart sensing fabrics for live bacteria detection 

    Ferrer-Vilanova, Amparo; Ivanova, Kristina Dimitrova; Diaz-Gonzalez, Maria; Alonso, Yasmine; Guirado, Gonzalo; Tzanov, Tzanko; Muños-Berbel, Xavier (Multidisciplinary Digital Publishing Institute (MDPI), 2018-11-27)
    Article
    Accés obert
    A smart textile for live bacteria detection of antimicrobial hospital tissues is here proposed. The capacity to detect viable bacteria is based on the use of Prussian Blue (PB) as electrochromic compound, with a clear ...
  • Enzymatic synthesis of a thiolated chitosan-based wound dressing crosslinked with chicoric acid 

    Stefanov, Ivaylo; Hinojosa Caballero, Dolores; Maspoch, Santiago; Hoyo Pérez, Javier; Tzanov, Tzanko (Royal Society of Chemistry (RSC), 2018-10-26)
    Article
    Accés obert
    This work describes the enzymatic synthesis of multifunctional hydrogels for chronic wound treatment using thiolated chitosan and the natural polyphenol chicoric acid. Gelation was achieved by ...
  • New myeloperoxidase detection system based on enzyme-catalysed oxidative synthesis of a dye for paper-based diagnostic devices 

    Bassegoda Puigdomenech, Arnau; Ferreres Cabanes, Guillem; Pérez Rafael, Silvia; Hinojosa-Caballero, Dolores; Torrent Burgués, Juan; Tzanov, Tzanko (2018-10-21)
    Article
    Accés restringit per política de l'editorial
    The severity and cost of wound infections strongly demands for simple and fast methods for wound infection determination. Point-of-care testing devices play a crucial role in order to achieve a fast diagnosis and early ...
  • Inhibition of quorum-sensing: A new paradigm in controlling bacterial virulence and biofilm formation 

    Asenova Ivanova, Aleksandra; Ivanova, Kristina Dimitrova; Tzanov, Tzanko (Springer Nature, 2018-05-31)
    Capítol de llibre
    Accés restringit per política de l'editorial
    Bacterial pathogens coordinate the expression of multiple virulence factors and formation of biofilms in cell density dependent manner, through a phenomenon named quorum sensing (QS). Protected in the biofilm community, ...
  • Thermodynamic behaviour of mixed films of an unsaturated and a saturated polar lipid : (Oleic Acid-Stearic Acid and POPC-DPPC) 

    Torrent Burgués, Juan (Multidisciplinary Digital Publishing Institute (MDPI), 2018-06)
    Article
    Accés obert
    Mixed fatty acids or mixed phospholipids systems with saturated-unsaturated hydrocarbon chains are of biological interest. In this work, the monolayers of oleic acid-stearic acid (OA-SA) and palmitoyloleoylphosphatidylch ...
  • Bottom-up layer-by-layer assembling of antibacterial freestanding nanobiocomposite films 

    Francesko, Antonio; Ivanova, Kristina Dimitrova; Hoyo Pérez, Javier; Pérez-Rafael, Silvia; Petkova, Petya; Fernandes Macedo, Margarida Maria; Heinze, Thomas; Mendoza Gómez, Ernesto; Tzanov, Tzanko (2018-07-27)
    Article
    Accés restringit per política de l'editorial
    In this study, freestanding nanobiocomposite films were obtained by the sequential deposition of biopolymer-capped silver nanoparticles (AgNPs) and hyaluronic acid (HA). At first, dispersions ofAgNPs decorated with chitosan ...
  • The Langmuir technique applied to the study of natural tears 

    Guaus Guerrero, Ester; Torrent Burgués, Juan (Springer, 2018-06-01)
    Article
    Accés restringit per política de l'editorial
    As a new proposal, natural tears collected from the Schirmer strips were studied using surface pressure-area, p-A, isotherms obtained with the Langmuir technique. Parameters such as limit surface pressure, plimit, elastic ...
  • Thylakoid membrane bioenergetics 

    Guaus Guerrero, Ester; Torrent Burgués, Juan; Hoyo Pérez, Javier (Elsevier, 2018-04-23)
    Capítol de llibre
    Accés restringit per política de l'editorial
    Oxygenic photosynthesis is a unique and essential photochemical process in which solar energy is used to oxidize water and to form carbohydrates. In this process molecular oxygen is released as a by-product. Thylakoid ...
  • Designing Peptidomimetics 

    Pérez González, Juan Jesús (2018-07-02)
    Article
    Accés restringit per política de l'editorial
    The concept of a peptidomimetic was coined about forty years ago. Since then, an enormous effort and interest has been devoted to mimic the properties of peptides with small molecules or pseudopeptides. The present report ...

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