Envíos recientes

  • Two-stage designs versus European scaled average designs in bioequivalence studies for highly variable drugs: which to choose? 

    Molins Lleonart, Eduard; Cobo Valeri, Erik; Ocaña Rebull, Jordi (2017-12)
    Artículo
    Acceso restringido por política de la editorial
    The usual approach to determine bioequivalence for highly variable drugs is scaled average bioequivalence, which is based on expanding the limits as a function of the within-subject variability in the reference formulation. ...
  • Selection of composite binary endpoints in clinical trials 

    Bofill Roig, Marta; Gómez Melis, Guadalupe (2017-10-12)
    Artículo
    Acceso restringido por política de la editorial
    The choice of a primary endpoint is an important issue when designing a clinical trial. It is common to use composite endpoints as a primary endpoint because it increases the number of observed events, captures more ...
  • Multi-depot rural postman problems 

    Fernández Aréizaga, Elena; Rodríguez Pereira, Jessica (Springer, 2017-07-01)
    Artículo
    Acceso restringido por política de la editorial
    This paper studies multi-depot rural postman problems on an undirected graph. These problems extend the well-known undirected rural postman problem to the case where there are several depots instead of just one. Linear ...
  • Minimum Spanning Trees with neighborhoods: mathematical programming formulations and solution methods 

    Blanco, Víctor; Fernández Aréizaga, Elena; Puerto Albandoz, Justo (Elsevier, 2017-11-01)
    Artículo
    Acceso restringido por política de la editorial
    This paper studies Minimum Spanning Trees under incomplete information assuming that it is only known that vertices belong to some neighborhoods that are second order cone representable and distances are measured with a ...
  • Using specification and description language for life cycle assesment in buildings 

    Fonseca Casas, Pau; Fonseca Casas, Antoni (2017-06-10)
    Artículo
    Acceso abierto
    The definition of a Life Cycle Assesment (LCA) for a building or an urban area is a complex task due to the inherent complexity of all the elements that must be considered. Furthermore, a multidisciplinary approach is ...
  • In-patient costs of agitation and containment in a mental health catchment area 

    Serrano-Blanco, Antoni; Rubio-Valera, Maria; Aznar, Ignacio; Baladón, Luisa; Gibert, Karina; Gracia Canales, Alfredo; Kaskens, Lisette; Ortiz, José Miguel; Salvador Carulla, Luís (2017-06-06)
    Artículo
    Acceso abierto
    Background: There is a scarce number of studies on the cost of agitation and containment interventions and their results are still inconclusive. We aimed to calculate the economic consequences of agitation events in an ...
  • Pharmacokinetics in morbid obesity: influence of two bariatric surgery techniques on paracetamol and caffeine metabolism 

    Goday Arno, Albert; Farré, Magí; Rodriguez Morato, Jose; Ramon, Jose M.; Perez Maña, Clara; Papaseit, Esther; Civit, Ester; Langohr, Klaus; Li Carbo, Marcel; De la Torre Fornell, Rafael (2017-05-30)
    Artículo
    Acceso restringido por política de la editorial
    The purpose of the study was to study the impact of the two most common bariatric surgery techniques on paracetamol pharmacokinetics (a marker of gastric emptying) and caffeine metabolism (a marker of liver function). In ...
  • Stochastic optimal generation bid to electricity markets with emissions risk constraints 

    Heredia, F.-Javier (Francisco Javier); Cifuentes Rubiano, Julián; Corchero García, Cristina (2018-02-01)
    Artículo
    Acceso abierto
    There are many factors that influence the day-ahead market bidding strategies of a generation company (GenCo) within the framework of the current energy market. Environmental policy issues are giving rise to emission ...
  • Are CONSORT checklists submitted by authors adequately reflecting what information is actually reported in published papers? 

    Blanco de Tena Davila, David; Biganne, Alice M.; Cobo Valeri, Erik (2018-01-29)
    Artículo
    Acceso abierto
    Background: Compulsory submission of a checklist from the relevant reporting guideline is one of the most widespread journal requirements aiming to improve completeness of reporting. However, the current suboptimal levels ...
  • Virtual mobility lab: a systemic approach to urban mobility challenges 

    Barceló Bugeda, Jaume; Montero Mercadé, Lídia; Ros Roca, Xavier (2018-01)
    Report de recerca
    Acceso abierto
  • Ordered Weighted Average optimization in Multiobjective Spanning Tree Problem 

    Fernández Aréizaga, Elena; Pozo, Miguel Angel; Puerto Albandoz, Justo; Scozzari, Andre (Elsevier, 2017-08-01)
    Artículo
    Acceso abierto
    Rework adversely impacts the performance of building projects. In this study, data were analyzed from 788 construction incidents in 40 Spanish building projects to determine the effects of project and managerial characteristics ...
  • The flexible periodic vehicle routing problem 

    Archetti, C; Fernández Aréizaga, Elena; Huerta Muñoz, Diana Lucia (2017-09)
    Artículo
    Acceso restringido por política de la editorial
    This paper introduces the Flexible Periodic Vehicle Routing Problem (FPVRP) where a carrier has to establish a distribution plan to serve his customers over a planning horizon. Each customer has a total demand that must ...

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