Electrochemical detection of dopamine based on a PVA/PEDOT: PSS thin film electrode
Tutor / directorTorras Costa, Juan
Document typeBachelor thesis
Rights accessOpen Access
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This project is part of a trans-national training network: the BioInspireSensing project, whose purpose is producing biosensors for pressure, temperature, and acidity. The aim of this study is fabricating a biosensor for the electrochemical sensing of dopamine using an all-organic system consisting of 3D printed polylactic acid (PLA), poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) tracks, and poly(vinyl alcohol) (PVA)-PEDOT:PSS thin film electrode. In this project, a 3D printed PLA track has been used as a substrate on top of which two different structures have been engineered through drop casting: first a conductive track of PEDOT:PSS and then the actual TFE, based on PVA and PEDOT:PSS. The electroactivity of the final device has been tested through electrochemical techniques: cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) and was improved through electropolymerization. In addition, the sensing properties of the device have been proven effective in the electrochemical detection of dopamine. The main three objectives of this work were: the optimization of the PEDOT:PSS track thickness; the study of the effects of electropolymerization on the TFE electroactivity; the determination of the sensing properties of the system to specific biomolecules. The relevance of the object of this study lies in the employment of a system that is all-organic and in the electrochemical detection of dopamine.