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dc.contributor.authorDíaz Rizzolo, Diana Alícia
dc.contributor.authorAcar Denizli, Nihan
dc.contributor.authorKostov, Belchin Adriyanov
dc.contributor.authorRoura, Elena
dc.contributor.authorSisó-Almirall, Antoni
dc.contributor.authorDelicado Useros, Pedro Francisco
dc.contributor.authorGomis de Barbarà, Ramon
dc.contributor.otherUniversitat Politècnica de Catalunya. Departament d'Estadística i Investigació Operativa
dc.date.accessioned2023-04-27T09:34:47Z
dc.date.available2023-04-27T09:34:47Z
dc.date.issued2022-06-01
dc.identifier.citationDíaz, D. [et al.]. Glycaemia fluctuations improvement in old-age prediabetic subjects consuming a quinoa-based diet: a pilot study. "Nutrients", 1 Juny 2022, vol. 14, núm. 11, article 2331.
dc.identifier.issn2072-6643
dc.identifier.urihttp://hdl.handle.net/2117/386766
dc.description.abstractThis study aimed to observe if quinoa could produce a benefit on postprandial glycemia that would result in less progression to type 2 diabetes (T2D). A cross-over design pilot clinical study with a nutritional intervention for 8 weeks was performed: 4 weeks on a regular diet (RD) and 4 weeks on a quinoa diet (QD). Nine subjects aged =65 years with prediabetes were monitored during the first 4 weeks of RD with daily dietary records and FreeStyle Libre®. Subsequently, participants started the QD, where quinoa and 100% quinoa-based products replaced foods rich in complex carbohydrates that they had consumed in the first 4 weeks of RD. The glycemic measurements recorded by the sensors were considered as functions of time, and the effects of nutrients consumed at the intended time period were analyzed by means of a function-on-scalar regression (fosr) model. With QD participants, decreased body weight (-1.6 kg, p = 0.008), BMI (-0.6 kg/m2p = 0.004) and waist circumference (-1.5 cm, p = 0.015) were observed. Nutrients intake changed during QD, namely, decreased carbohydrates (p = 0.004) and increased lipids (p = 0.004) and some amino acids (p < 0.05). The fosr model showed a reduction in postprandial glycemia in QD despite intrapersonal differences thanks to the joint action of different nutrients and the suppression of others consumed on a regular diet. We conclude that in an old age and high T2D-risk population, a diet rich in quinoa reduces postprandial glycemia and could be a promising T2D-preventive strategy.
dc.language.isoeng
dc.rightsAttribution 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectÀrees temàtiques de la UPC::Ciències de la salut::Medicina
dc.subject.lcshDiabetes
dc.subject.lcshNutrition
dc.subject.otherNutrition
dc.subject.otherDiabetes
dc.subject.otherQuinoa
dc.subject.otherDiet
dc.subject.otherPrevention
dc.subject.otherGlycaemia
dc.titleGlycaemia fluctuations improvement in old-age prediabetic subjects consuming a quinoa-based diet: a pilot study
dc.typeArticle
dc.subject.lemacDiabetis
dc.subject.lemacNutrició
dc.contributor.groupUniversitat Politècnica de Catalunya. ADBD - Anàlisi de Dades Complexes per a les Decisions Empresarials
dc.identifier.doi10.3390/nu14112331
dc.description.peerreviewedPeer Reviewed
dc.relation.publisherversionhttps://www.mdpi.com/2072-6643/14/11/2331
dc.rights.accessOpen Access
local.identifier.drac35729514
dc.description.versionPostprint (published version)
local.citation.authorDíaz, D.; Acar-Denizli, N.; Kostov, B.; Roura, E.; Sisó-Almirall, A.; Delicado, P.; Gomis, R.
local.citation.publicationNameNutrients
local.citation.volume14
local.citation.number11, article 2331


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