BDNF and cortisol in the diagnosis of cocaine-induced depression
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hdl:2117/375774
Tipus de documentArticle
Data publicació2022-03-15
EditorFrontiers Media SA
Condicions d'accésAccés obert
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Reconeixement 4.0 Internacional
Abstract
Major depressive disorder (MDD) and cocaine use disorder (CUD) are related with disability and high mortality rates. The assessment and treatment of psychiatric comorbidity is challenging due to its high prevalence and its clinical severity, mostly due to suicide rates and the presence of medical comorbidities. The aim of this study is to investigate differences in brain derived neurotrophic factor (BDNF) and cortisol plasmatic levels in patients diagnosed with CUD-primary-MDD and CUD-induced-MDD and also to compare them to a sample of MDD patients (without cocaine use), a sample of CUD (without MDD), and a group of healthy controls (HC) after a stress challenge.
Descripció
Copyright © 2022 Fonseca, Mestre-Pinto, Rodríguez-Minguela, Papaseit, PérezMañá, Langohr, Barbuti, Farré, Torrens andNEURODEP GROUP. This is an openaccess article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
CitacióFonseca, F. [et al.]. BDNF and cortisol in the diagnosis of cocaine-induced depression. "Frontiers in psychiatry", 15 Març 2022, vol. 13, núm. 836771.
ISSN1664-0640
Versió de l'editorhttps://www.frontiersin.org/articles/10.3389/fpsyt.2022.836771/full
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