The landscape of virus-host protein–protein interaction databases
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Cita com:
hdl:2117/375154
Tipus de documentArticle
Data publicació2022-07-15
EditorFrontiers Media SA
Condicions d'accésAccés obert
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Reconeixement 4.0 Internacional
Abstract
Knowledge of virus-host interactomes has advanced exponentially in the last decade by the use of high-throughput screening technologies to obtain a more comprehensive landscape of virus-host protein–protein interactions. In this article, we present a systematic review of the available virus-host protein–protein interaction database resources. The resources covered in this review are both generic virus-host protein–protein interaction databases and databases of protein–protein interactions for a specific virus or for those viruses that infect a particular host. The databases are reviewed on the basis of the specificity for a particular virus or host, the number of virus-host protein–protein interactions included, and the functionality in terms of browse, search, visualization, and download. Further, we also analyze the overlap of the databases, that is, the number of virus-host protein–protein interactions shared by the various databases, as well as the structure of the virus-host protein–protein interaction network, across viruses and hosts.
CitacióValiente, G. The landscape of virus-host protein–protein interaction databases. "Frontiers in microbiology", 15 Juliol 2022, vol. 13, article 827742, p. 1-11.
ISSN1664-302X
Versió de l'editorhttps://www.frontiersin.org/articles/10.3389/fmicb.2022.827742/full
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fmicb-13-827742.pdf | 1,416Mb | Visualitza/Obre |