El grup està especialitzat en la síntesi i l'estudi de propietats de nous polímers. Aquests corresponen majoritàriament a materials biodegradables, per la qual cosa ens hem centrat en les tècniques que permeten el seguiment del procés de degradació (hidrolític, enzimàtic o tèrmic). També es fa l'estudi de les seves aplicacions com a sistemes dosificadors de fàrmacs (preparació de micropartícules, incorporació de l'agent actiu i seguiment del seu alliberament). Els materials es caracteritzen a través de les tècniques espectroscòpiques habituals i se?n determinen les propietats tèrmiques i mecàniques.
Les propietats dels materials polimèrics depenen de la manera com s'organitzen les macromolècules, per la qual cosa també s'estudien les fases amorfes i les diferents fases cristal·lines. La determinació de l'estructura cristal·lina es fa combinant tècniques de difracció de raigs X (pols o fibra), microscòpia electrònica i simulació molecular. També es fa la resolució, per mètodes directes i per difracció amb mon

The team specialises in the synthesis of new polymers, their physical and chemical characterisation, and the study of their properties. It is mainly involved in the development of biodegradable polymers and the study of degradation processes (hydrolytic, enzymatic and thermal). The applications of polymers as drug delivery systems are considered. The study of amorphous content and crystalline phases is also undertaken. The crystalline structures are determined by X-ray diffraction (powder or fibre), electron microscopy and molecular simulation. Direct methods are applied to monocrystals of small model compounds that are representative of polymer sequences. Research is also carried out into crystal growth (from solution or from the melt state) and the kinetics of crystallisation.

The team specialises in the synthesis of new polymers, their physical and chemical characterisation, and the study of their properties. It is mainly involved in the development of biodegradable polymers and the study of degradation processes (hydrolytic, enzymatic and thermal). The applications of polymers as drug delivery systems are considered. The study of amorphous content and crystalline phases is also undertaken. The crystalline structures are determined by X-ray diffraction (powder or fibre), electron microscopy and molecular simulation. Direct methods are applied to monocrystals of small model compounds that are representative of polymer sequences. Research is also carried out into crystal growth (from solution or from the melt state) and the kinetics of crystallisation.

Recent Submissions

  • Cell responses to electrical pulse stimulation for anticancer drug release 

    Puiggalí Jou, Anna; Valle Mendoza, Luis Javier del; Alemán Llansó, Carlos (Multidisciplinary Digital Publishing Institute (MDPI), 2019-08-01)
    Article
    Open Access
    Electrical stimulation is an attractive approach to tune on-demand drug release in the body as it relies on simple setups and requires typically 1 V or less. Although many studies have been focused on the development of ...
  • Crystalline structures and structural transitions of copolyamides derived from 1,4-diaminobutane and different ratios of glutaric and azelaic acids 

    Olmo, Cristian; Casas Becerra, María Teresa; Martínez Guil, Juan Carlos; Franco García, María Lourdes; Puiggalí Bellalta, Jordi (Multidisciplinary Digital Publishing Institute (MDPI), 2019-04-01)
    Article
    Open Access
    Copolyamides derived from even 1,4-butanediamine and different mixtures of odd dicarboxylic acids with a great difference in the number of methylene groups (i.e., glutaric and azelaic acids with 3 and 7 groups, respectively) ...
  • Preparation of medicated polylactide micropieces by means of ultrasonic technology 

    Olmo, Cristian; Franco García, María Lourdes; Valle Mendoza, Luis Javier del; Puiggalí Bellalta, Jordi (Multidisciplinary Digital Publishing Institute, 2019-06-01)
    Article
    Open Access
    A technology based on the application of ultrasound as an energy source was applied to get polylactide (PLA) micropieces with minimum degradation and processing time. This requirement could be even shorter than 1.5 s. The ...
  • Crystallization kinetics of chain extended poly(L-lactide)s having different molecular structures 

    Yousefzade, Omid; Jeddi, Javad; Franco García, María Lourdes; Puiggalí Bellalta, Jordi; Garmabi, Hamid (2020-01-15)
    Article
    Restricted access - publisher's policy
    Poly(L-lactide)s (PLLAs) with different chain structures were prepared by reactive melt processing and using Joncryl ADR as chain extender. Results of gel permeation chromatography (GPC) revealed that chain extended PLLAs ...
  • Nanocomposites based on chain extended poly(l-lactic acid)/carboxylated carbon nanotubes: crystallization kinetics and lamellar morphology 

    Yousefzade, Omid; Franco García, María Lourdes; Nami, Mahsa; Puiggalí Bellalta, Jordi; Garmabi, Hamid (2019-06-01)
    Article
    Open Access
    Isothermal and nonisothermal crystallization kinetics of poly(l-lactide) and its nanocomposites with different multiwalled carbon nanotubes (i.e., pristine and functionalized) were investigated. The effects of chain extension ...
  • Non-isothermal crystallization kinetics of poly(4-hydroxybutyrate) biopolymer 

    Keridou, Ina; Valle Mendoza, Luis Javier del; Funk, Lutz; Turon, Pau; Franco García, María Lourdes; Puiggalí Bellalta, Jordi (2019-08-05)
    Article
    Open Access
    The non-isothermal crystallization of the biodegradable poly(4-hydroxybutyrate) (P4HB) has been studied by means of differential scanning calorimetry (DSC) and polarizing optical microscopy (POM). In the first case, Avrami, ...
  • Isothermal crystallization kinetics of poly(4-hydroxybutyrate) biopolymer 

    Keridou, Ina; Valle Mendoza, Luis Javier del; Funk, Lutz; Turon, Pau; Yousef, Ibraheem; Franco García, María Lourdes; Puiggalí Bellalta, Jordi (Multidisciplinary Digital Publishing Institute (MDPI), 2019-08-01)
    Article
    Open Access
    Thermal properties and crystallization kinetics of poly(4-hydroxybutyrate) (P4HB) have been studied. The polymer shows the typical complex melting behavior associated to different lamellar populations. Annealing processes ...
  • Biomimetic hybrid membranes: incorporation of transport proteins/peptides into polymer supports 

    Puiggalí Jou, Anna; Valle Mendoza, Luis Javier del; Alemán Llansó, Carlos (2019-01-01)
    Article
    Restricted access - publisher's policy
    Molecular sensing, water purification and desalination, drug delivery, and DNA sequencing are some striking applications of biomimetic hybrid membranes. These devices take advantage of biomolecules, which have gained ...
  • Antimicrobial activity of poly(3,4-ethylenedioxythiophene) n-doped with a pyridinium-containing polyelectrolyte 

    Sánchez Jiménez, Margarita; Estrany Coda, Francesc; Borràs Cristòfol, Núria; Maiti, Binoy; Díaz Díaz, David; Valle Mendoza, Luis Javier del; Alemán Llansó, Carlos (2019-08-30)
    Article
    Restricted access - publisher's policy
    In spite of p-doped conducting polymers having been widely studied in the last decades and many applications having been developed, studies based on n-doped conducting polymers are extremely scarce. This fact is even more ...
  • Scaffolds for sustained release of ambroxol hydrochloride, a pharmacological Chaperone that Increases the Activity of Misfolded ß-Glucocerebrosidase 

    Enshaei, Hamidreza; Molina, Brenda G.; Valle Mendoza, Luis Javier del; Estrany Coda, Francesc; Arnan, Carme; Puiggalí Bellalta, Jordi; Saperas Plana, Núria; Alemán Llansó, Carlos (2019-01-01)
    Article
    Restricted access - publisher's policy
    Ambroxol is a pharmacological chaperone (PC) for Gaucher disease that increases lysosomal activity of misfolded ß-glucocerebrosidase (GCase) while displaying a safe toxicological profile. In this work, different ...
  • Hydrogels for flexible and compressible free standing cellulose supercapacitors 

    Saborío González, Maricruz; Svelic, Petra; Casanovas Salas, Jordi; Ruano Torres, Guillem; Pérez Madrigal, María del Mar; Franco García, María Lourdes; Torras Costa, Juan; Estrany Coda, Francesc; Alemán Llansó, Carlos (Elsevier, 2019-09-01)
    Article
    Restricted access - publisher's policy
    Cellulose-based supercapacitors display important advantages in comparison with devices fabricated with other materials, regarding environmental friendliness, flexibility, cost and versatility. Recent progress in the field ...
  • Sustained release of a pharmacological chaperone that increases the activity of misfolded ß-Glucocerebrosidase 

    Enshaei, Hamidreza; Molina García, Brenda Guadalupe; Valle Mendoza, Luis Javier del; Estrany Coda, Francesc; Arnan, Carme; Puiggalí Bellalta, Jordi; Saperas Plana, Núria; Alemán Llansó, Carlos (2019)
    Conference lecture
    Open Access

View more