Widefield SERS for High-Throughput Nanoparticle Screening
Cita com:
hdl:2117/361685
Tipus de documentArticle
Data publicació2022-02-02
EditorWiley
Condicions d'accésAccés obert
Llevat que s'hi indiqui el contrari, els
continguts d'aquesta obra estan subjectes a la llicència de Creative Commons
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Reconeixement 3.0 Espanya
ProjecteVISUALIZACION EN 3D DE PROCESOS DINAMICOS EN CELULAS VIVAS (AEI-RTI2018-099957-J-I00)
LightNet - LightNet (EC-H2020-670949)
INTEGRAL STAGING, PROGNOSTIC AND DIAGNOSTIC OF CANCER IN LIQUID SAMPLES THROUGH OPTICAL METHODS (AEI-PID2020-120306RB-I00)
LightNet - LightNet (EC-H2020-670949)
INTEGRAL STAGING, PROGNOSTIC AND DIAGNOSTIC OF CANCER IN LIQUID SAMPLES THROUGH OPTICAL METHODS (AEI-PID2020-120306RB-I00)
Abstract
Surface-enhanced Raman scattering (SERS) imaging is a powerful technology with unprecedent potential for ultrasensitive chemical analysis. Point-by-point scanning and often excessively long spectral acquisition-times hamper the broad exploitation of the full analytical potential of SERS. Here, we introduce large scale SERS particle screening (LSSPS), a multiplexed widefield screening approach to particle-characterization, which is 500-1000 times faster than typical confocal Raman implementations. Beyond its higher throughput, LSSPS simultaneously quantifies both the sample’s Raman and Rayleigh scattering, allowing for an unprecedented correlation of SERS activity with the particle-size and to directly quantify the fraction of SERS active particles.
CitacióLiebel, M. [et al.]. Widefield SERS for High-Throughput Nanoparticle Screening. "Angewandte Chemie", 2 Febrer 2022, vol. 2022, núm. e202200072.
Versió de l'editorhttps://onlinelibrary.wiley.com/doi/10.1002/anie.202200072?af=R
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Angewandte Chem ... particle Screening (1).pdf | 1,596Mb | Visualitza/Obre |