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Application of ultrasound-assisted compression and 3D-printing semi-solid extrusion techniques to the development of sustained-release drug delivery systems based on a novel biodegradable aliphatic copolyester
(2024-05)
Article
Open AccessThe purpose of this study was to investigate the ability of two advanced hot-processing technologies, Ultrasound-Assisted Compression (USAC) and 3D-printing Semi-solid Extrusion (SSE), to manufacture sustained-release drug ... -
Enzymatic degradation behavior of self-degradable lipase-embedded aliphatic and aromatic polyesters and their blends
(2024-06-10)
Article
Open AccessOver the past decade, the preparation of novel materials by enzyme-embedding into biopolyesters has been proposed as a straightforward method to produce self-degrading polymers. This paper reports the preparation and ... -
Challenging isodimorphism concepts: formation of three crystalline phases in poly(hexamethylene-ran-octamethylene carbonate) copolymers
(American Chemical Society (ACS), 2023-10-11)
Article
Open AccessIn this work, poly(hexamethylene-ran-octamethylene carbonate) copolycarbonates were synthesized by melt polycondensation in a wide range of compositions. The copolymers displayed some of the characteristic isodimorphic ... -
Disappearance of melt memory effect with comonomer incorporation in isodimorphic random copolyesters
(American Chemical Society (ACS), 2023-09-21)
Article
Open AccessMelt memory effects in polymer crystallization have attracted much attention in the past few years. Although progress has been made in understanding how the chemical structure of polymers can affect melt memory, there are ... -
Synthesis of functionalized triblock copolyesters derived from lactic acid and macrolactones for bone tissue regeneration
(2023-04-09)
Article
Open AccessSynthetic and functional grafts are a great alternative to conventional grafts. They can provide a physical support and the precise signaling for cells to heal damaged tissues. In this study, a novel RGD peptide ... -
Enzymatic crosslinked hydrogels of gelatin and poly (vinyl alcohol) loaded with probiotic bacteria as oral delivery system
(Multidisciplinary Digital Publishing Institute (MDPI), 2022-12-09)
Article
Open AccessProbiotic bacteria are widely used to prepare pharmaceutical products and functional foods because they promote and sustain health. Nonetheless, probiotic viability is prone to decrease under gastrointestinal conditions. ... -
Hydrophobic modification of poly(gamma-glutamic acid) by grafting 4-phenyl-butyl side groups for the encapsulation and release of doxorubicin
(Multidisciplinary Digital Publishing Institute (MDPI), 2023-05-16)
Article
Open AccessThe delivery of drugs is a great challenge, since most of active pharmaceutical ingredients developed today are hydrophobic and poorly water soluble. From this perspective, drug encapsulation on biodegradable and biocompatible ... -
Tunable enzymatic biodegradation of poly(butylene succinate): biobased coatings and self-degradable films
(Elsevier, 2023-05-01)
Article
Open AccessBiodegradation of polyesters driven by enzymes is considered as one of the most effective way of degradation of these materials, as a way to control plastics accumulation in the environment. In this study, we present two ... -
IberWQ: new simulation tool for 2D water quality modelling in rivers and shallow estuaries
(2016-09)
Article
Open AccessThis paper presents a new freeware simulation tool (IberWQ) for 2D water quality modelling in rivers and non-stratified estuaries. The model computes the spatial and temporal evolution of several species and variables which ... -
Elastomeric copolyesters of omega-pentadecalactone and cyclohexylenedimethylene succinate obtained by enzymatic polymerization
(Elsevier, 2023-01)
Article
Open AccessThe use of renewable monomers and green polymerization processes for preparing new synthetic polymers is a hot topic today. In this work we have obtained high molecular weight copolyesters derived from ¿-pentadecalactone ... -
Enzymatic recycling of polymacrolactones
(2022-02-16)
Article
Open AccessThe use of renewable monomers to make new polyesters which could replace the ones obtained from petrochemical resources employing green processes is attracting a lot of attention these days. With this in mind, three different ... -
Green metallic nanoparticles for cancer therapy: evaluation models and cancer applications
(2021-10-18)
Article
Open AccessMetal-based nanoparticles are widely used to deliver bioactive molecules and drugs to improve cancer therapy. Several research works have highlighted the synthesis of gold and silver nanoparticles by green chemistry, using ...
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