Effect of different antibiotic chemotherapies on pseudomonas aeruginosa infection in vitro of primary human corneal fibroblast cells

Cendra Gascón, María del Mar; Christodoulides, Myron; Hossain, Parwez

doi:10.3389/fmicb.2017.01614

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Cendra Gascón, María del Mar

Christodoulides, Myron

Hossain, Parwez

Document typeArticle

Defense date2017-08-22

PublisherFrontiers Media SA

Rights accessOpen Access

Except where otherwise noted, content on this work is licensed under a Creative Commons license : Attribution-NonCommercial-NoDerivs 3.0 Spain

Abstract

Pseudomonas aeruginosa is a major cause of bacterial keratitis (BK) worldwide. Inappropriate or non-optimal antibiotic chemotherapy can lead to corneal perforation and rapid sight loss. In this study, we tested the hypothesis that P. aeruginosa strain PAO1 invades primary human corneal fibroblasts (hCFs) in vitro and persists intracellularly, despite chemotherapy with antibiotics used commonly to treat BK

CitationCendra, M.; Christodoulides, M.; Hossain, P. Effect of different antibiotic chemotherapies on pseudomonas aeruginosa infection in vitro of primary human corneal fibroblast cells. "Frontiers in microbiology", 22 Agost 2017, vol. 8, núm. 1614, p. 1-13.

URIhttp://hdl.handle.net/2117/356905

DOI10.3389/fmicb.2017.01614

ISSN1664-302X

Publisher versionhttps://www.frontiersin.org/articles/10.3389/fmicb.2017.01614/full

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Departament d'Enginyeria Agroalimentària i Biotecnologia - Articles de revista [987]

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Effect of different antibiotic chemotherapies on pseudomonas aeruginosa infection in vitro of primary human corneal fibroblast cells

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