Computational modeling of single cell migration
Tutor / directorSáez Viñas, Pablo
Document typeBachelor thesis
Rights accessOpen Access
Cell migration is central to any biological process such as embryonic development, wound healing or cancer. Here we study the mechanisms the cell uses when moving as well as the main proteins involved like actin and myosin. We also focus on the initial polarization of the cell and how the cell responds to external stimulus. We center on two kind of polarization: chemical cues and stiffness gradients of the substrate. In this thesis we also show how we solve the model equations, which are coupled PDEs, by combining a finite element scheme with a Crank-Nicolson method.
DegreeGRAU EN MATEMÀTIQUES (Pla 2009)