Articles de revista
Envíos recientes
-
Evolution of tandem repeat satellite sequences in two closely related caenorhabditis species: Diminution of satellites in hermaphrodites
(2017-12-01)
Artículo
Acceso abiertoThe availability of the genome sequence of the unisexual (male-female) Caenorhabditis nigoni offers an opportunity to compare its non-coding features with the related hermaphroditic species Caenorhabditis briggsae; to ... -
Effect of solvent choice on the self-assembly properties of a diphenylalanine amphiphile stabilized by an ion pair
(2017-07-19)
Artículo
Acceso restringido por política de la editorialA diphenylalanine (FF) amphiphile blocked at the C terminus with a benzyl ester (OBzl) and stabilized at the N terminus with a trifluoroacetate (TFA) anion was synthetized and characterized. Aggregation of peptide molecules ... -
Functional and structural analysis of AT-specific minor groove binders that disrupt DNA-protein interactions and cause disintegration of the Trypanosoma brucei kinetoplast
(2017-08-21)
Artículo
Acceso abiertoTrypanosoma brucei, the causative agent of sleeping sickness (Human African Trypanosomiasis, HAT), contains a kinetoplast with the mitochondrial DNA (kDNA), comprising of >70% AT base pairs. This has prompted studies of ... -
Paternal contribution to development: sperm genetic damage and repair in fish
(2017-04-01)
Artículo
Acceso abiertoIn this review we provide an overview of the components of the spermatozoa playing an important role in reproductive success beyond fertilization, showing the relationship between the integrity of the diverse elements and ... -
Crystalline structure and thermotropic behavior of alkyltrimethylphosphonium amphiphiles
(2017-02-14)
Artículo
Acceso abiertoQuaternary organophosphonium salts bearing long alkyl chains are cationic surfactants of interest owing to their physical and biological properties. In the present work, the crystal structure and thermotropic behavior of ... -
Intercalative DNA binding of the marine anticancer drug variolin B
(Macmillan Publishers, 2017-01-04)
Artículo
Acceso abiertoVariolin B is a rare marine alkaloid that showed promising anti-cancer activity soon after its isolation. It acts as a cyclin-dependent kinase inhibitor, although the precise mechanism through which it exerts the cytotoxic ... -
Paternal contribution to development: Spermgenetic damage and repair in fish
(2016)
Artículo
Acceso abiertoIn this review we provide an overview of the components of the spermatozoa playing an important role in reproductive success beyond fertilization , showing the relationship between the integrity of the diverse elements and ... -
Spermiogenesis and biflagellate spermatozoon of the teleost fish Lampanyctus crocodilus (Myctophiformes, Myctophidae): ultrastructure and characterisation of its sperm basic nuclear proteins
(2015-08-01)
Artículo
Acceso abiertoWe undertook an ultrastructural study of the spermiogenesis of the lanternfish Lampanyctus crocodilus (Myctophiformes, Myctophidae) with special emphasis on the condensation of chromatin and the biochemical characterisation ... -
High evolutionary turnover of satellite families in Caenorhabditis
(2015-10-05)
Artículo
Acceso abiertoBackground: The high density of tandem repeat sequences (satellites) in nematode genomes and the availability of genome sequences from several species in the group offer a unique opportunity to better understand the ... -
Two high-mobility group box domains act together to underwind and kink DNA.
(2015-07-02)
Artículo
Acceso abiertoHigh-mobility group protein 1 (HMGB1) is an essential and ubiquitous DNA architectural factor that influences a myriad of cellular processes. HMGB1 contains two DNA-binding domains, box A and box B, which have little ... -
Structure of the DNA duplex d(ATTAAT)(2) with Hoogsteen hydrogen bonds
(2015-03-17)
Artículo
Acceso abiertoThe traditional Watson-Crick base pairs in DNA may occasionally adopt a Hoogsteen conformation, with a different organization of hydrogen bonds. Previous crystal structures have shown that the Hoogsteen conformation is ... -
Aplicación al aprendizaje de técnicas de purificación y análisis de proteínas
(2014)
Artículo
Acceso abiertoA menudo el aprendizaje de técnicas experimentales en el laboratorio se ofrece en forma de prácticas independientes inconexas en las que el alumno aprende una o unas pocas de ellas en cada sesión. ...
RSS 1.0