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Model-driven exploration of poro-viscoelasticity in human brain tissue: be careful with the parameters!
(2024-12-06)
Article
Open AccessThe brain is arguably the most complex human organ and modelling its mechanical behaviour has challenged researchers for decades. There is still a lack of understanding on how this multiphase tissue responds to mechanical ... -
Development of a multi-fidelity optimisation strategy based on hybrid methods
(Springer, 2024-09-14)
Article
Open AccessA multi-fidelity optimisation strategy has been developed in the present work, and its performance is illustrated through a series of test cases. The strategy is based on hybrid methods such that two genetic optimisation ... -
On the efficient and accurate non-linear computational modeling of multilayered bending plates. State of the art and a novel proposal: the 2D+ multiscale approach
(2024-07)
Article
Open AccessAfter conducting a comprehensive historical review of presently established methods for computational modeling of multilayered bending plates, the present work introduces a novel 2D multiscale strategy, termed the 2D+ ... -
Sound transmission loss enhancement through triple-peak coupled resonances acoustic metamaterials
(2024-03-15)
Article
Open AccessCoupled resonances mechanisms combined with the notion of acoustic metamaterials offer exceptional sound insulation capabilities, even at the challenging low frequency ranges below 1000 Hz. In this context, the concept of ... -
Machine learning in solid mechanics: Application to acoustic metamaterial design
(John Wiley & sons, 2024-07-30)
Article
Open AccessMachine learning (ML) and Deep learning (DL) are increasingly pivotal in the design of advanced metamaterials, seamlessly integrated with material or topology optimization. Their intrinsic capability to predict and ... -
Optimal design of Multiresonant Layered Acoustic Metamaterials (MLAM) via a homogenization approach
(Elsevier, 2023-10)
Article
Open AccessBroadband sound attenuation at low frequency ranges (below 500 Hz) has been a challenge in the acoustics field which cannot be solved, via conventional materials, unless impractical amounts of mass are employed. Multiresonant ... -
Poro-viscoelastic material parameter identification of brain tissue-mimicking hydrogels
(Frontiers Media SA, 2023-04-10)
Article
Open AccessUnderstanding and characterizing the mechanical and structural properties of brain tissue is essential for developing and calibrating reliable material models. Based on the Theory of Porous Media, a novel nonlinear ... -
The role of computational models in mechanobiology of growing bone
(Frontiers Media SA, 2022-11-18)
Article
Open AccessEndochondral ossification, the process by which long bones grow in length, is regulated by mechanical forces. Computational models, specifically finite element models, have been used for decades to understand the role of ... -
I’m stuck! How to efficiently debug computational solid mechanics models so you can enjoy the beauty of simulations
(2023-01)
Article
Open AccessA substantial fraction of the time that computational modellers dedicate to developing their models is actually spent trouble-shooting and debugging their code. However, how this process unfolds is seldom spoken about, ... -
Coiled phononic crystal with periodic rotational locking: subwavelength bragg band gaps
(American Physical Society (APS), 2022-07-15)
Article
Open AccessPhononic crystals (PnC) are spatially periodic materials with band gaps that form by Bragg scattering of elastic waves. Within the frequency range of a band gap, wave propagation is not admitted. A long-standing limitation ... -
Usability of deep learning pipelines for 3D nuclei identification with Stardist and Cellpose
(Elsevier, 2022-12)
Article
Open AccessSegmentation of 3D images to identify cells and their molecular outputs can be difficult and tedious. Machine learning algorithms provide a promising alternative to manual analysis as emerging 3D image processing technology ... -
Local mechanical stimuli correlate with tissue growth in axolotl salamander joint morphogenesis
(2022-05-25)
Article
Open AccessMovement-induced forces are critical to correct joint formation, but it is unclear how cells sense and respond to these mechanical cues. To study the role of mechanical stimuli in the shaping of the joint, we combined ...
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