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dc.contributor.authorSerafini Immich, Ana
dc.contributor.authorTornero García, José Antonio
dc.contributor.authorCano Casas, Francesc
dc.contributor.authorLis Arias, Manuel José
dc.contributor.otherUniversitat Politècnica de Catalunya. Departament de Ciència i Enginyeria de Materials
dc.contributor.otherUniversitat Politècnica de Catalunya. Doctorat en Enginyeria Tèxtil i Paperera
dc.contributor.otherUniversitat Politècnica de Catalunya. Departament d'Enginyeria Química
dc.identifier.citationSerafini, A. [et al.]. Diffusional approach on electrospun PLLA membranes for caffeine delivery. A: "Advanced aspects of engineering research vol. 6". Book publisher international, 2021, p. 67-79.
dc.description.abstractOne of the great advantages of electrospun fibers is the large tridimensional area produced, capable of storing any type of material. The aim of our investigation is to study the electrospinning technique to produce polymer membranes for drug delivery applications, given their large surface area and ability to transport a bioactive compound. A mathematical modeling of the delivery system kinetics was also studied to find the mechanism that controls the releasing process. Results showed that electrospinning could provide regular and smooth membranes suitable for drug delivery processes. The choice of a proper solvent for this process was an important parameter analyzed, because it determined whether fibers were capable of forming, as well as influencing fiber porosity. The mathematical modeling also proved that thicker PLLA membranes exhibited a Fickian diffusion behavior during the drug transport, presenting better control in drug delivery processes
dc.description.sponsorshipThe authors are grateful to CAPES for financial support
dc.format.extent13 p.
dc.publisherBook publisher international
dc.subjectÀrees temàtiques de la UPC::Enginyeria dels materials
dc.subject.lcshNanostructured materials
dc.subject.lcshDrug delivery systems
dc.subject.lcshMembranes (Technology)
dc.subject.otherSandwich structures
dc.subject.otherDiffusion coefficients
dc.titleDiffusional approach on electrospun PLLA membranes for caffeine delivery
dc.typePart of book or chapter of book
dc.subject.lemacMaterials nanoestructurats
dc.subject.lemacMedicaments -- Modes d'administració
dc.subject.lemacMembranes (Tecnologia)
dc.subject.lemacPolylactic acid
dc.contributor.groupUniversitat Politècnica de Catalunya. TECTEX - Grup de Recerca en Tecnologia Tèxtil
dc.contributor.groupUniversitat Politècnica de Catalunya. POLQUITEX - Materials Polimérics i Química Téxtil
dc.rights.accessRestricted access - publisher's policy
dc.description.versionPostprint (published version)
local.citation.authorSerafini, A.; Tornero, J.; Cano, F.; Lis, M.
local.citation.publicationNameAdvanced aspects of engineering research vol. 6

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