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dc.contributor.authorEgozcue Rubí, Juan José
dc.contributor.authorGraffelman, Jan
dc.contributor.authorOrtego Martínez, María Isabel
dc.contributor.authorPawlowsky Glahn, Vera
dc.contributor.otherUniversitat Politècnica de Catalunya. Departament d'Enginyeria Civil i Ambiental
dc.contributor.otherUniversitat Politècnica de Catalunya. Departament d'Estadística i Investigació Operativa
dc.date.accessioned2021-02-09T08:57:45Z
dc.date.available2021-02-09T08:57:45Z
dc.date.issued2020-12-01
dc.identifier.citationEgozcue, J.J. [et al.]. Some thoughts on counts in sequencing studies. "NAR Genomics and Bioinformatics", 1 Desembre 2020, vol. 2, núm. 4, p. 1-10.
dc.identifier.issn2631-9268
dc.identifier.urihttp://hdl.handle.net/2117/337113
dc.description.abstractMeasurements in sequencing studies are mostly based on counts. There is a lack of theoretical developments for the analysis and modelling of this type of data. Some thoughts in this direction are presented, which might serve as a seed. The main issues addressed are the compositional character of multinomial probabilities and the corresponding representation in orthogonal (isometric) coordinates, and modelling distributions for sequencing data taking into account possible effects of amplification techniques.
dc.format.extent10 p.
dc.language.isoeng
dc.subjectÀrees temàtiques de la UPC::Matemàtiques i estadística::Matemàtica aplicada a les ciències
dc.subject.lcshBiomathematics
dc.titleSome thoughts on counts in sequencing studies
dc.typeArticle
dc.subject.lemacBiomatemàtica
dc.contributor.groupUniversitat Politècnica de Catalunya. COSDA-UPC - COmpositional and Spatial Data Analysis
dc.identifier.doi10.1093/nargab/lqaa094
dc.description.peerreviewedPeer Reviewed
dc.subject.amsClassificació AMS::92 Biology and other natural sciences::92B Mathematical biology in general
dc.relation.publisherversionhttps://academic.oup.com/nargab/article/2/4/lqaa094/5996081
dc.rights.accessOpen Access
local.identifier.drac30483610
dc.description.versionPostprint (published version)
local.citation.authorEgozcue, J. J.; Graffelman, J.; Ortego, M.I.; Pawlowsky, V.
local.citation.publicationNameNAR Genomics and Bioinformatics
local.citation.volume2
local.citation.number4
local.citation.startingPage1
local.citation.endingPage10


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