Towards tissue reconstruction, using 3D hydrogel-based scaffolds
Estadístiques de LA Referencia / Recolecta
Inclou dades d'ús des de 2022
Cita com:
hdl:2117/333952
Tipus de documentProjecte Final de Màster Oficial
Data2020-07-16
Condicions d'accésAccés obert
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Abstract
In the last decades, the European countries have been fighting against an increasing incidence of cancer. If we take a look in the statistics, we will see that breast cancer has been the highest burden between females, having a really big impact in women living in Belgium. Luckily, Belgium has one of the highest survival rates of breast cancer. This, however, often implies the excision of the patient’s breast, or at least a part of it. This generates the following dilemma: how to reconstruct the breast with the functionalities of the original one and with the minimum cost for the patient, both medically and economically. Nowadays there are three clinical approaches that try to recover the initial breast: medical implants, lipofilling and microsurgical free tissue transplantation. These however have their own drawback and this thesis will try to tackle this by focusing on adipose tissue engineering, as being part of a bigger research lead by the Polymer Chemistry and Biomaterials of the University of Gent (PBM). It is going to discuss some materials and methods that can be used for tissue regeneration, from a practical point of view with the principal goal to set the next pathways to apply these materials. You are going to see all the process, from the synthesis of different hydrogels, going through the processing of several scaffolds with direct and indirect 3D printing, for finally doing the characterization of these products, in order to analyze the properties that were looking for. It is concluded that tissue engineering is a really interesting field of study in order to be applied in medical sciences although it is still in an initial phase for breast reconstruction.
TitulacióMÀSTER UNIVERSITARI EN ENGINYERIA INDUSTRIAL (Pla 2014)
Col·leccions
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towards-tissue- ... drogel-based-scaffolds.pdf | 2,028Mb | Visualitza/Obre |