Show simple item record

dc.contributor.authorPensalfini, Marco
dc.contributor.authorRotach, Mathias
dc.contributor.authorHopf, Raoul
dc.contributor.authorBielicki, A.
dc.contributor.authorSantoprete, Roberto
dc.contributor.authorMazza, Edoardo
dc.date.accessioned2020-11-30T11:32:19Z
dc.date.available2020-11-30T11:32:19Z
dc.date.issued2020-10-01
dc.identifier.citationPensalfini, M. [et al.]. How cosmetic tightening products modulate the biomechanics and morphology of human skin. "Acta biomaterialia", 1 Octubrer 2020, vol. 115, núm. October, p. 299-316.
dc.identifier.issn1742-7061
dc.identifier.urihttp://hdl.handle.net/2117/333490
dc.description.abstractThe active and passive mechanical behavior of a cosmetic tightening product for skin anti-aging is investigated based on a wide range of in vivo and in vitro measurements. The experimental data are used to inform a numerical model of the attained cosmetic effect, which is then implemented in a commercial finite-element framework and used to analyze the mechanisms that regulate the biomechanical interaction between the native tissue and the tightening film. Such a film reduces wrinkles and enhances skin consistency by increasing its stiffness by 48-107% and reducing inelastic, non-recoverable deformations (-47%). The substrate deformability influences both the extent of tightening and the reduction of wrinkle amplitude. The present findings allow, for the first time, to rationalize the mechanisms of action of cosmetic products with a tightening action and provide quantitative evidence for further optimization of this fascinating class of biomaterials.
dc.format.extent18 p.
dc.language.isoeng
dc.publisherElsevier
dc.rightsAttribution 3.0 Spain
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/
dc.subjectÀrees temàtiques de la UPC::Enginyeria dels materials::Disseny i selecció de materials
dc.subject.lcshCosmetics--Analysis
dc.subject.otherSkin tightening
dc.subject.otherSoft tissue biomechanics
dc.subject.otherMaterial characterization
dc.subject.otherConstitutive modeling
dc.subject.otherMechanobiology
dc.titleHow cosmetic tightening products modulate the biomechanics and morphology of human skin
dc.typeArticle
dc.subject.lemacCosmètics -- Anàlisi
dc.identifier.doi10.1016/j.actbio.2020.08.027
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S1742706120304876
dc.rights.accessOpen Access
local.identifier.drac29884385
dc.description.versionPostprint (published version)
local.citation.authorPensalfini, M.; Rotach, M.; Hopf, R.; Bielicki, A.; Santoprete, R.; Mazza, E.
local.citation.publicationNameActa biomaterialia
local.citation.volume115
local.citation.numberOctober
local.citation.startingPage299
local.citation.endingPage316


Files in this item

Thumbnail

This item appears in the following Collection(s)

    Show simple item record

    Attribution 3.0 Spain
    Except where otherwise noted, content on this work is licensed under a Creative Commons license : Attribution 3.0 Spain