Estimation of synaptic conductances using control theory

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hdl:2117/330636
Document typeMaster thesis
Date2020-10
Rights accessOpen Access
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Attribution-NonCommercial-NoDerivs 3.0 Spain
Abstract
Unveiling the input a neuron receives and distinguishing between excitation and inhibition provides information on local connectivity and brain operating conditions. However, experimental techniques do not allow direct recordings of synaptic inputs, and thus inverse methods are sought to retrieve synaptic currents/conductances from cell voltage. We propose a new method to estimate synaptic currents in neuron models using control theory (equivalent control and robust exact differentiation) and disentangle excitatory from inhibitory synaptic conductances.
DegreeMÀSTER UNIVERSITARI EN MATEMÀTICA AVANÇADA I ENGINYERIA MATEMÀTICA (Pla 2010)
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