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dc.contributor.authorBuxadera Palomero, Judit
dc.contributor.authorGodoy Gallardo, María
dc.contributor.authorMolmeneu Trias, Meritxell
dc.contributor.authorPunset Fuste, Miquel
dc.contributor.authorGil Mur, Francisco Javier
dc.contributor.otherUniversitat Politècnica de Catalunya. Departament de Ciència i Enginyeria de Materials
dc.date.accessioned2020-10-20T08:30:50Z
dc.date.available2020-10-20T08:30:50Z
dc.date.issued2020-04-01
dc.identifier.citationBuxadera-Palomero, J. [et al.]. Antibacterial properties of triethoxysilylpropyl succinic anhydride silane (TESPSA) on titanium dental implants. "Polymers", 1 Abril 2020, vol. 12, núm. 4, p. 773/1-773/15.
dc.identifier.issn2073-4360
dc.identifier.urihttp://hdl.handle.net/2117/330466
dc.description.abstractInfections related to dental implants are a common complication that can ultimately lead to implant failure, and thereby carries significant health and economic costs. In order to ward off these infections, this paper explores the immobilization of triethoxysilylpropyl succinic anhydride (TESPSA, TSP) silane onto dental implants, and the interaction of two distinct monospecies biofilms and an oral plaque with the coated titanium samples. To this end, titanium disks from prior machining were first activated by a NaOH treatment and further functionalized with TESPSA silane. A porous sodium titanate surface was observed by scanning electron microscopy and X-ray photoelectron spectroscopy analyses confirmed the presence of TESPSA on the titanium samples (8.4% for Ti–N-TSP). Furthermore, a lactate dehydrogenase assay concluded that TESPSA did not have a negative effect on the viability of human fibroblasts. Importantly, the in vitro effect of modified surfaces against Streptococcus sanguinis, Lactobacillus salivarius and oral plaque were studied using a viable bacterial adhesion assay. A significant reduction was achieved in all cases but, as expected, with different effectiveness against simple mono-species biofilm (ratio dead/live of 0.4) and complete oral biofilm (ratio dead/live of 0.6). Nevertheless, this approach holds a great potential to provide dental implants with antimicrobial properties.
dc.language.isoeng
dc.publisherMultidisciplinary Digital Publishing Institute (MDPI)
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectÀrees temàtiques de la UPC::Enginyeria dels materials
dc.subject.lcshBiomedical materials
dc.subject.lcshDental implants
dc.subject.lcshTitanium
dc.subject.otherTitanium
dc.subject.otherTriethoxysilylpropyl succinic anhydride (TESPSA)
dc.subject.otherBacterial adhesion
dc.subject.otherAntibacterial
dc.subject.otherBiofilm
dc.subject.otherSilane
dc.titleAntibacterial properties of triethoxysilylpropyl succinic anhydride silane (TESPSA) on titanium dental implants
dc.typeArticle
dc.subject.lemacTitani -- Aplicacions mèdiques
dc.subject.lemacMaterials biomèdics
dc.subject.lemacImplants dentals
dc.contributor.groupUniversitat Politècnica de Catalunya. BBT - Biomaterials, Biomecànica i Enginyeria de Teixits
dc.identifier.doi10.3390/polym12040773
dc.description.peerreviewedPeer Reviewed
dc.rights.accessOpen Access
local.identifier.drac28618099
dc.description.versionPostprint (published version)
dc.contributor.covenanteeUniversitat Internacional de Catalunya
local.citation.authorBuxadera-Palomero, J.; Godoy-Gallardo, M.; Molmeneu, M.; Punset, M.; Gil, F.J.
local.citation.publicationNamePolymers
local.citation.volume12
local.citation.number4
local.citation.startingPage773/1
local.citation.endingPage773/15


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