BBT - Biomaterials, Biomecànica i Enginyeria de Teixits

 

El Grup de Biomaterials, Bioemecànica i Enginyeria de Teixits basa la seva recerca en el desenvolupament de biomaterials per a la regeneració i/o la reparació funcional de teixits i òrgans. Això comprèn el disseny de materials capaços de modular la resposta biològica del teixit receptor, donant lloc en alguns casos a la regeneració de teixits, i en altres a una perfecta integració del biomaterial, amb la recuperació funcional perduda.
El plantejament d'aquest objectiu és intrínsecament interdisciplinari, i exigeix d’una banda la caracterització dels materials a nivell físicoquímic i mecànic i, de l'altra, l'estudi de les seves interaccions amb les entitats biològiques a diferents nivells -proteïnes, cèl·lules i teixits-.
La recerca duta a terme pel grup BBT abasta tant aspectes fonamentals com d'altres més tecnològics, susceptibles de ser transferits a empreses del sector biomèdic.

El Grupo de Biomateriales, Biomecánica e Ingeniería de Tejidos basa su investigación en el desarrollo de biomateriales para la regeneración y / o la reparación funcional de tejidos y órganos. Esto comprende el diseño de materiales capaces de modular la respuesta biológica del tejido receptor, dando lugar en algunos casos a la regeneración de tejidos, y en otros a una perfecta integración del biomaterial, con la recuperación funcional perdida. El planteamiento de este objetivo es intrínsecamente interdisciplinario, y exige por un lado la caracterización de los materiales a nivel físico-químico y mecánico y, por otro, el estudio de sus interacciones con las entidades biológicas a diferentes niveles -proteínas, celulas y tejidos-.La investigación llevada a cabo por el grupo BBT abarca tanto aspectos fundamentales como otros más tecnológicos, susceptibles de ser transferidos a empresas del sector biomédico.

The Biomaterials, Biomechanics and Tissue Engineering Group carries out research into the development of biomaterials for the regeneration and/or functional repair of tissues and organs. There is a demand for the design of materials that are able to modulate the biological response of receiving tissues. In some cases this ability leads to the regeneration and neoformation of degraded tissue, and in others, the perfect integration of the biomaterial and the recovery of the lost function.

The Biomaterials, Biomechanics and Tissue Engineering Group carries out research into the development of biomaterials for the regeneration and/or functional repair of tissues and organs. There is a demand for the design of materials that are able to modulate the biological response of receiving tissues. In some cases this ability leads to the regeneration and neoformation of degraded tissue, and in others, the perfect integration of the biomaterial and the recovery of the lost function.

Recent Submissions

  • Cyclic deformation fatigue behaviour of Ti6Al4V thermochemically nitrided for articular prostheses 

    Gil Mur, Francisco Javier; Manero Planella, José María; Rodríguez Rius, Daniel; Planell Estany, Josep Anton (2003)
    Article
    Open Access
    Titanium and its alloys have many attractive properties including high specific strength, low density, and excellent corrosion resistance. Titanium and the Ti6Al4V alloy have long been recognized as materials with high ...

  • Self-healable and eco-friendly hydrogels for flexible supercapacitors 

    Babeli Aguilera, Ismael; Ruano Torres, Guillem; Puiggalí Jou, Anna; Ginebra Molins, Maria Pau; Alemán Llansó, Carlos; García Torres, José Manuel (Wiley (John Wiley & Sons), 2021-03-11)
    Article
    Restricted access - publisher's policy
    One limitation of wearable electronics, and at the same time a challenge, is the lack of energy storage devices with multiple functionalities produced using clean and environmental-friendly strategies. Here, a multifunctional ...

  • Corrosion resistance and ion release of dental prosthesis of COCR obtained by CAD-CAM milling, casting and laser sintering 

    Padrós, Roberto; Giner Tarrida, Lluís; Herrero Climent, Mariano; Punset Fuste, Miquel; Gil Mur, Javier (Multidisciplinary Digital Publishing Institute (MDPI), 2020-06-01)
    Article
    Open Access
    Covenantee:   Barcelona Dental Institute / Universitat Internacional de Catalunya / Porto Dental Institute
    Corrosion resistance and ion release behavior have been evaluated for thirty dental restoration samples obtained by three different manufacturing systems: computer-aided design and manufacturing (CAD-CAM), traditional ...

  • Kinetics and products of air plasma induced oxidation in water of imidacloprid and thiamethoxam treated individually and in mixture 

    Tampieri, Francesco; Durighello, Alessandro; Biondo, Omar; Gasior, Marcelina; Knys, Aleksandra; Marotta, Ester; Paradisi, Cristina (2019-05)
    Article
    Open Access
    Imidacloprid (I) and thiamethoxam (T) are widely used neonicotinoid insecticides with high persistence in the environment and thus included in the watch list of substances for European Union-wide monitoring reported in the ...

  • Positive effect of cold atmospheric nitrogen plasma on the behavior of mesenchymal stem cells cultured on a bone scaffold containing iron oxide-loaded silica nanoparticles catalyst 

    Przekora, Agata; Audemar, Maïté; Pawlat, Joanna; Canal Barnils, Cristina; Thomann, Jean-Sébastien; Labay, Cédric Pierre (2020-07-03)
    Article
    Open Access
    Covenantee:   Uniwersytet Medyczny w Lublinie / Université Catholique de Louvain / Politechnika Lubelska / Luxembourg Institute of Science and Technology
    Low-temperature atmospheric pressure plasma was demonstrated to have an ability to generate different reactive oxygen and nitrogen species (RONS), showing wide biological actions. Within this study, mesoporous silica ...

  • Application of fluorescence-based probes for the determination of superoxide in water treated with air non-thermal plasma 

    Cabrellon, Gabriele; Tampieri, Francesco; Rossa, Andrea; Barbon, Antonio; Marotta, Ester; Paradisi, Cristina (2020-09-25)
    Article
    Restricted access - publisher's policy
    Superoxide is one of the reactive oxygen species (ROS) in non-thermal plasmas generated by electrical discharges in air at room temperature and atmospheric pressure. One important application of such plasmas is the activation ...

  • Radicals and ions formed in plasma-treated organic solvents: a mechanistic investigation to rationalize the enhancement of electrospinnability of polycaprolactont 

    Grande, Silvia; Tampieri, Francesco; Nikiforov, Anton; Giardina, Agata; Barbon, Antonio; Cools, Pieter; Morent, Rino; Paradisi, Cristina; Marotta, Ester; De Geyter, Nathalie (2019-05-16)
    Article
    Open Access
    This paper reports and discusses the beneficial effects on the quality of electrospun polycaprolactone nanofibers brought about by pretreatment of the solvent with non-thermal plasma. Chloroform/dimethylformamide 9:1 ...

  • Propulsion and energetics of a minimal magnetic microswimmer 

    Calero, Carles; García Torres, José Manuel; Ortiz, Antonio; Sagues, Francesc; Pagonabarraga, Ignacio; Tierno, Pietro (Royal Society of Chemistry, 2020-07-28)
    Article
    Restricted access - publisher's policy
    In this manuscript we describe the realization of a minimal hybrid microswimmer, composed of a ferromagnetic nanorod and a paramagnetic microsphere. The unbounded pair is propelled in water upon application of a swinging ...

  • Electrodeposición de recubrimientos de fosfato de calcio sobre titanio 

    Rupérez de Gracia, Elisa; Rodríguez Rius, Daniel; Vidal Girona, Elia (2018)
    Article
    Open Access
    El titanio y sus aleaciones son biomateriales usados frecuentemente en implantes y prótesis. Sin embargo, estos biomateriales metálicos tienen limitaciones relacionadas con la bioactividad. Una vía para aumentar la ...

  • An engineered biomimetic peptide regulates cell behavior by synergistic integrin and growth factor signaling 

    Oliver Cervelló, Lluís; Martín Gómez, Helena; Reyes, Leslie; Noureddine, Fatima; Cavalcanti-Adam, Elisabetta Ada; Ginebra Molins, Maria Pau; Mas Moruno, Carlos (2020-12-18)
    Article
    Restricted access - publisher's policy
    Covenantee:   Max-Planck-Institut für medizinische Forschung
    Recreating the healing microenvironment is essential to regulate cell–material interactions and ensure the integration of biomaterials. To repair bone, such bioactivity can be achieved by mimicking its extracellular matrix ...

  • Effect of allogeneic cell-based tissue-engineered treatments in a sheep osteonecrosis model 

    López Fernández, Alba; Barro Ojed, Víctor; Ortiz Hernández, Mónica; Manzanares, Maria Cristina; Ginebra Molins, Maria Pau; Vives Armengol, Joaquim; Velez Villa, Roberto; Aguirre Canyadell, Màrius (2020-03-27)
    Article
    Open Access
    Covenantee:   Universitat Autònoma de Barcelona / Vall d'Hebron Institut de Recerca / Hospital Universitari Vall d'Hebron / Universitat de Barcelona
    Osteonecrosis of the femoral head (ONFH) is defined as a tissue disorder and successive subchondral bone collapse resulting from an ischemic process, which may progress to hip osteoarthritis. Cell therapy with multipotent ...

  • Chemically diverse multifunctional peptide platforms with antimicrobial and cell adhesive properties 

    Martín Gómez, Helena; Oliver Cervelló, Lluís; Buxadera Palomero, Judit; Ginebra Molins, Maria Pau; Mas Moruno, Carlos (2020-01-01)
    Article
    Restricted access - publisher's policy
    Bacterial infections and incomplete biomaterial integration are major problems that can lead to the failure of medical implants. However, simultaneously addressing these two issues remains a challenge. Here, we present a ...

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