BBT - Biomaterials, Biomecànica i Enginyeria de Teixits

 

El Grup de Biomaterials, Bioemecànica i Enginyeria de Teixits basa la seva recerca en el desenvolupament de biomaterials per a la regeneració i/o la reparació funcional de teixits i òrgans. Això comprèn el disseny de materials capaços de modular la resposta biològica del teixit receptor, donant lloc en alguns casos a la regeneració de teixits, i en altres a una perfecta integració del biomaterial, amb la recuperació funcional perduda.
El plantejament d'aquest objectiu és intrínsecament interdisciplinari, i exigeix d’una banda la caracterització dels materials a nivell físicoquímic i mecànic i, de l'altra, l'estudi de les seves interaccions amb les entitats biològiques a diferents nivells -proteïnes, cèl·lules i teixits-.
La recerca duta a terme pel grup BBT abasta tant aspectes fonamentals com d'altres més tecnològics, susceptibles de ser transferits a empreses del sector biomèdic.

El Grupo de Biomateriales, Biomecánica e Ingeniería de Tejidos basa su investigación en el desarrollo de biomateriales para la regeneración y / o la reparación funcional de tejidos y órganos. Esto comprende el diseño de materiales capaces de modular la respuesta biológica del tejido receptor, dando lugar en algunos casos a la regeneración de tejidos, y en otros a una perfecta integración del biomaterial, con la recuperación funcional perdida. El planteamiento de este objetivo es intrínsecamente interdisciplinario, y exige por un lado la caracterización de los materiales a nivel físico-químico y mecánico y, por otro, el estudio de sus interacciones con las entidades biológicas a diferentes niveles -proteínas, celulas y tejidos-.La investigación llevada a cabo por el grupo BBT abarca tanto aspectos fundamentales como otros más tecnológicos, susceptibles de ser transferidos a empresas del sector biomédico.

The Biomaterials, Biomechanics and Tissue Engineering Group carries out research into the development of biomaterials for the regeneration and/or functional repair of tissues and organs. There is a demand for the design of materials that are able to modulate the biological response of receiving tissues. In some cases this ability leads to the regeneration and neoformation of degraded tissue, and in others, the perfect integration of the biomaterial and the recovery of the lost function.

The Biomaterials, Biomechanics and Tissue Engineering Group carries out research into the development of biomaterials for the regeneration and/or functional repair of tissues and organs. There is a demand for the design of materials that are able to modulate the biological response of receiving tissues. In some cases this ability leads to the regeneration and neoformation of degraded tissue, and in others, the perfect integration of the biomaterial and the recovery of the lost function.

Recent Submissions

  • Bioactive macroporous titanium implants highly interconnected 

    Caparrós, Cristina; Ortiz Hernández, Mónica; Molmeneu Trias, Meritxell; Punset Fuste, Miquel; Calero Martínez, José Antonio; Aparicio Badenas, Conrado José; Fernández Fairén, Mariano; Pérez Antoñanzas, Román; Gil Mur, Francisco Javier (Springer, 2016-10-01)
    Article
    Restricted access - publisher's policy
    Intervertebral implants should be designed with low load requirements, high friction coefficient and low elastic modulus in order to avoid the stress shielding effect on bone. Furthermore, the presence of a highly ...

  • Microstructure and surface damage in retrieved metal-on-metal hip arthroplasties 

    Fernández Fairén, Mariano; Punset Fuste, Miquel; Gilabert Cervera, Javier (2017-12-01)
    Article
    Restricted access - publisher's policy
    Background: Besides promising results of metal-on-metal (MOM) hip arthroplasty (HA), frequent failures have been reported even in the short term. Many host, surgical, design, metallurgical, and processing factors have been ...

  • Can we remove tattoos with non-thermal atmospheric plasma? 

    Tampieri, Francesco; Garcìa Araguz, Ariadna; Canal Barnils, Cristina (Wiley (John Wiley & Sons), 2022-01-01)
    Article
    Open Access
    Current methods for tattoo removal are long, costly and have drawbacks such as scarring among others. Looking for alternatives, here we assess the feasibility of non-thermal plasma (NTP) as a standalone method for the ...

  • Selectively targeting tumorigenicity in osteosarcoma 

    Tornin Cavielles, Juan; Mateu Sanz, Miguel; Rey, Verónica; Murillo, Dzohara; Huergo, Carmen; Rodríguez, Aida; Rodríguez, René; Canal Barnils, Cristina (Universitat Politècnica de Catalunya, 2022-03-14)
    Dataset
    Open Access

  • Maturation of biomimetic hydroxyapatite in physiological fluids: a physicochemical and proteomic study 

    Konka, Joanna Magdalena; Español Pons, Montserrat; Bosch Canals, Begoña María; de Oliveira, Eliandre; Ginebra Molins, Maria Pau (Elsevier, 2021-09-01)
    Article
    Open Access
    Covenantee:   Universitat Internacional de Catalunya / Parc Científic de Barcelona / Institut de Bioenginyeria de Catalunya
    Biomimetic calcium-deficient hydroxyapatite (CDHA) as a bioactive material exhibits exceptional intrinsic osteoinductive and osteogenic properties because of its nanostructure and composition, which promote a favorable ...

  • Intrapericardial delivery of APA-microcapsules as promising stem cell therapy carriers in an experimental acute myocardial infarction model 

    Báez Diaz, Claudia; Blanco Blázquez, Virginia; Sánchez Margallo, Francisco M.; López, Esther; Martin, Helena; Espona Noguera, Albert; Casado, Javier; Ciriza, Jesús; Pedraz, Jose Luis; Crisóstomo, Verónica (2021-11-01)
    Article
    Open Access
    The administration of cardiosphere-derived cells (CDCs) after acute myocardial infarction (AMI) is very promising. CDC encapsulation in alginate-poly-l-lysine-alginate (APA) could increase cell survival and adherence. The ...

  • Zirconia vs. titanium dental implants: primary stability in-vitro analysis 

    Arlucea, Nerea; Brizuela Velasco, Aritza; Diéguez Pereira, Markel; Punset Fuste, Miquel; Molmeneu Trias, Meritxell; Sánchez Lasheras, Fernando; De Llanos Lanchares, Hector; Álvarez Arenal, Ángel (Multidisciplinary Digital Publishing Institute (MDPI), 2021-12-20)
    Article
    Open Access
    Covenantee:   Universidad de Oviedo / Instituto Universitario de Ciencias y Tecnologías Espaciales de Asturias (ICTEA)
    The present experimental trial uses two types of dental implants, one made of titanium (Ti6Al4V) and the other one of zirconia (ZrO2), but both of identical design, to compare their stability and micro-movements values ...

  • Biomedical applications of powder metallurgy 

    Rodríguez Contreras, Alejandra María; Punset Fuste, Miquel; Manero Planella, José María; CALERO, JOSE ANTONIO; Torres Garrido, Diego (Elsevier, 2021-09-01)
    Part of book or chapter of book
    Restricted access - publisher's policy
    The performance and properties of Titanium (Ti) and its alloys can be fully exploited for biomedical applications such as orthopedic and dental implants, when porous structures are used. Such Ti structures can matched the ...

  • Hybrid conducting alginate-based hydrogel for hydrogen peroxide detection from enzymatic oxidation of lactate 

    Babeli Aguilera, Ismael; Puiggalí Jou, Anna; Roa Rovira, Joan Josep; Ginebra Molins, Maria Pau; García Torres, José Manuel; Alemán Llansó, Carlos (Elsevier, 2021-12-15)
    Article
    Restricted access - publisher's policy
    Covenantee:   Institut de Bioenginyeria de Catalunya
    A conducting nanocomposite hydrogel is developed for the detection of L-lactate. The hydrogel is based on a mixture of alginate (Alg) and poly(3,4-ethylenedioxythiophene) (PEDOT), which is loaded with gold nanoparticles ...

  • a-tricalcium phosphate synthesis from amorphous calcium phosphate: structural characterization and hydraulic reactivity 

    Martínez, Thomas; Español Pons, Montserrat; Charvillat, Cedric; Marsan, Olivier; Ginebra Molins, Maria Pau; Rey, Christian; Sarda, Stephanie (Springer, 2021-05-24)
    Article
    Open Access
    Covenantee:   Université de Toulouse / Institut de Bioenginyeria de Catalunya
    In the present study, amorphous tricalcium phosphate (TCP) has been synthetized by a wet route to obtain low temperature a-TCP at 650 °C (LT-aTCP) and compare its structural, physical–chemical and thermal properties with ...

  • Bactericidal silver-doped DLC coatings obtained by pulsed filtered cathodic arc co-deposition 

    Rupérez de Gracia, Elisa; Guillem Martí, Jordi; Lousa, Arturo; Punset Fuste, Miquel; Ortiz Hernández, Mónica (Elsevier, 2021-02)
    Article
    Restricted access - publisher's policy
    Covenantee:   Fundació Eurecat / Universitat de Barcelona / Asociación de la Industria Navarra
    Diamond-like carbon (DLC) coatings have been extensively studied over the last two decades in the field of materials engineering. The addition of effective bactericidal agents like silver suggests the potential application ...

  • Membrane perturbation, altered morphology and killing of Staphylococcus epidermidis upon contact with a cytocompatible peptide-based antibacterial surface 

    Boix Lemonche, Gerard; Guillem Martí, Jordi; Lekka, Maria; D'Este, Francesca; Guida, Filomena; Manero Planella, José María; Skerlavaj, Barbara (2021-07-01)
    Article
    Restricted access - publisher's policy
    Covenantee:   Università degli Studi di Udine / Basque Research & Technology Alliance / Università degli studi di Trieste / Universitetet i Oslo
    One possibility to prevent prosthetic infections is to produce biomaterials resistant to bacterial colonization by anchoring membrane active antimicrobial peptides (AMPs) onto the implant surface. In this perspective, a ...

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