BBT - Grup de recerca en Biomaterials, Biomecànica i Enginyeria de Teixits
El Grup de Biomaterials, Bioemecànica i Enginyeria de Teixits basa la seva recerca en el desenvolupament de biomaterials per a la regeneració i/o la reparació funcional de teixits i òrgans. Això comprèn el disseny de materials capaços de modular la resposta biològica del teixit receptor, donant lloc en alguns casos a la regeneració de teixits, i en altres a una perfecta integració del biomaterial, amb la recuperació funcional perduda.
El plantejament d'aquest objectiu és intrínsecament interdisciplinari, i exigeix d’una banda la caracterització dels materials a nivell físicoquímic i mecànic i, de l'altra, l'estudi de les seves interaccions amb les entitats biològiques a diferents nivells -proteïnes, cèl·lules i teixits-.
La recerca duta a terme pel grup BBT abasta tant aspectes fonamentals com d'altres més tecnològics, susceptibles de ser transferits a empreses del sector biomèdic.
El Grupo de Biomateriales, Biomecánica e Ingeniería de Tejidos basa su investigación en el desarrollo de biomateriales para la regeneración y / o la reparación funcional de tejidos y órganos. Esto comprende el diseño de materiales capaces de modular la respuesta biológica del tejido receptor, dando lugar en algunos casos a la regeneración de tejidos, y en otros a una perfecta integración del biomaterial, con la recuperación funcional perdida. El planteamiento de este objetivo es intrínsecamente interdisciplinario, y exige por un lado la caracterización de los materiales a nivel físico-químico y mecánico y, por otro, el estudio de sus interacciones con las entidades biológicas a diferentes niveles -proteínas, celulas y tejidos-.La investigación llevada a cabo por el grupo BBT abarca tanto aspectos fundamentales como otros más tecnológicos, susceptibles de ser transferidos a empresas del sector biomédico.
The Biomaterials, Biomechanics and Tissue Engineering Group carries out research into the development of biomaterials for the regeneration and/or functional repair of tissues and organs. There is a demand for the design of materials that are able to modulate the biological response of receiving tissues. In some cases this ability leads to the regeneration and neoformation of degraded tissue, and in others, the perfect integration of the biomaterial and the recovery of the lost function.
The Biomaterials, Biomechanics and Tissue Engineering Group carries out research into the development of biomaterials for the regeneration and/or functional repair of tissues and organs. There is a demand for the design of materials that are able to modulate the biological response of receiving tissues. In some cases this ability leads to the regeneration and neoformation of degraded tissue, and in others, the perfect integration of the biomaterial and the recovery of the lost function.
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Altres [1]
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Articles de revista [388]
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Dataset [3]
Recent Submissions
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Recent advances in the treatment of bone cancer with plasma-conditioned liquids
(2022)
Conference report
Open Access -
Lessons learnt with plasma-treated liquid therapies for bone cancer: opportunities for plasma medicine
(2022)
Conference report
Open Access -
Plasma-conditioned liquids in bone cancer therapy
(2022)
Conference report
Open Access -
Current state of cold atmospheric plasma and cancer-immunity cycle: therapeutic relevance and overcoming clinical limitations using hydrogels
(John Wiley & sons, 2023-01-20)
Article
Open AccessCold atmospheric plasma (CAP) is a partially ionized gas that gains attention as a well-tolerated cancer treatment that can enhance anti-tumor immune responses, which are important for durable therapeutic effects. This ... -
Intron-encoded cistronic transcripts for minimally invasive monitoring of coding and non-coding RNAs
(2022-11-07)
Article
Open Access
Covenantee: Helmholtz Zentrum München / Technische Universität München / Helmholtz Zentrum MünchenDespite their fundamental role in assessing (patho)physiological cell states, conventional gene reporters can follow gene expression but leave scars on the proteins or substantially alter the mature messenger RNA. ... -
Surface competition between osteoblasts and bacteria on silver-doped bioactive titanium implant
(Elsevier, 2023-01-24)
Article
Open Access
Covenantee: Institut de Recerca Sant Joan de Déu / Institut de Bioenginyeria de Catalunya / AMESThe rapid integration in the bone tissue and the prevention of bacterial infection are key for the success of the implant. In this regard, a silver (Ag)-doped thermochemical treatment that generate an Ag-doped calcium ... -
Ceramic-hydrogel composite as carrier for cold-plasma reactive-species: Safety and osteogenic capacity in vivo
(Wiley (John Wiley & Sons), 2022-01-01)
Article
Open Access
Covenantee: Institut de Recerca Sant Joan de Déu / Mimetis Biomaterials / Universitat Autònoma de Barcelona / Institut de Bioenginyeria de CatalunyaPlasma-treated hydrogels have been put forward as a potential selective osteosarcoma therapy through the release of reactive species to the diseased site. To allow their translation to the clinics, it is crucial to show ... -
Rheological characterisation of ceramic inks for 3D direct ink writing: A review
(Elsevier, 2021-12)
Article
Open Access3D printing is a competitive manufacturing technology, which has opened up new possibilities for the fabrication of complex ceramic structures and customised parts. Extrusion-based technologies, also known as direct ink ... -
Scaffold-based bone tissue engineering in microgravity: potential, concerns and implications
(2022-12-01)
Article
Open Access
Covenantee: Institut de Bioenginyeria de Catalunya / E. Amaldi FoundationOne of humanity’s greatest challenges is space exploration, which requires an in-depth analysis of the data continuously collected as a necessary input to fill technological gaps and move forward in several research sectors. ... -
Numerical simulation of the micro-extrusion process of printable biomaterials
(Scipedia, 2022)
Conference report
Open AccessThis work aims to gain a better understanding of how the rheological properties of printable materials affect their processability, as well as the quality of the final product, which at the end can lead to reducing time ... -
Hydroxyapatite nanoparticles-cell interaction: New approaches to disclose the fate of membrane-bound and internalised nanoparticles
(Elsevier, 2022-11-01)
Article
Open Access
Covenantee: Sincrotró ALBA / Maastricht University / Institut de Bioenginyeria de Catalunya / Nanyang Technological UniversityHydroxyapatite nanoparticles are popular tools in bone regeneration, but they have also been used for gene delivery and as anticancer drugs. Understanding their mechanism of action, particularly for the latter application, ... -
Functionalized silk promotes cell migration into calcium phosphate cements by providing macropores and cell adhesion motifs
(2022-11-01)
Article
Open Access
Covenantee: Kungliga Tekniska högskolan / Uppsala universitet / Institut de Bioenginyeria de CatalunyaCalcium phosphate cements (CPCs) are attractive synthetic bone grafts as they possess osteoconductive and osteoinductive properties. Their biomimetic synthesis grants them an intrinsic nano- and microporosity that resembles ...
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