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Cosmetotextiles with gallic acid: skin reservoir effect

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10.1155/2013/456248
 
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hdl:2117/26785

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Marti Gelabert, Meritxell
Alonso Merino, Cristina
Martínez Rodríguez, Vanessa
Lis Arias, Manuel JoséMés informacióMés informacióMés informació
de la Maza, Alfons
Parra Juez, José Luis
Coderch Negra, Luisa
Document typeArticle
Defense date2013-03-11
PublisherHINDAWI
Rights accessOpen Access
Attribution 3.0 Spain
Except where otherwise noted, content on this work is licensed under a Creative Commons license : Attribution 3.0 Spain
Abstract
The antioxidant gallic acid (GA) has been incorporated into cotton (CO) and polyamide (PA) through two different vehicles, that is, liposomes and mixed micelles, and their respective absorption/desorption processes have been studied. Moreover, in vitro percutaneous absorption tests of different cosmetotextiles have been performed to demonstrate antioxidant penetration within the layers of the skin. When GA was embedded into the cosmetotextiles, it always promoted a reservoir effect that was much more marked than that observed for polyamide. Similar penetration was observed in the textiles treated with GA in mixed micelles or liposomes in such compartments of the skin as the stratum corneum, epidermis, and even the dermis. GA was detected in receptor fluid only when CO was treated with MM. This methodology may be usef ul in verifying how encapsulate ed substances incorporated into textile materials penetrate human skin. Indeed, such materials can be considered strategic delivery systems that release a given active compound into the skin at specific doses
CitationMarti, M. [et al.]. Cosmetotextiles with gallic acid: skin reservoir effect. "Journal of Drug Delivery", 11 Març 2013, vol. 2013, p. 1-7. 
URIhttp://hdl.handle.net/2117/26785
DOI10.1155/2013/456248
ISSN2090-3022
Publisher versionhttp://www.hindawi.com/journals/jdd/2013/456248/
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