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Recent Submissions
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Human CASPR2 antibodies reversibly alter memory and the CASPR2 protein complex
(Wiley, 2022-03-07)
Article
Open AccessObjective The encephalitis associated with antibodies against contactin-associated protein-like 2 (CASPR2) is presumably antibody-mediated but the antibody effects and whether they cause behavioral alterations are not ... -
The nucleus measures shape changes for cellular proprioception to control dynamic cell behavior
(ACS, 2020-10-16)
Article
Open AccessSingle cells continuously experience and react to mechanical challenges in three-dimensional tissues. Spatial constraints in dense tissues, physical activity, and injury all impose changes in cell shape. How cells can ... -
Unravelling the Metabolic Progression of Breast Cancer Cells to Bone Metastasis by Coupling Raman Spectroscopy and a Novel Use of Mcr-Als Algorithm
(ACS, 2018-03-28)
Open AccessRaman spectroscopy (RS) has shown promise as a tool to reveal biochemical changes that occur in cancer processes at the cellular level. However, when analyzing clinical samples, RS requires improvements to be able to resolve ... -
Light-sheet microscopy: a tutorial
(OSA, 2018-01-19)
Article
Open AccessThis paper is intended to give a comprehensive review of light-sheet (LS) microscopy from an optics perspective. As such, emphasis is placed on the advantages that LS microscope configurations present, given the degree of ... -
Interference with Clp protease impairs carotenoid accumulation during tomato fruit ripening
(Society for Experimental Biology, 2018-01-29)
Article
Open AccessProfound metabolic and structural changes are required for fleshy green fruits to ripen and become colorful and tasty. In tomato (Solanum lycopersicum), fruit ripening involves the differentiation of chromoplasts, specialized ... -
Transcriptome analysis in tissue sectors with contrasting crocins accumulation provides novel insights into apocarotenoid biosynthesis and regulation during chromoplast biogenesis
(Nature, 2018-02-12)
Article
Open AccessCrocins, the red soluble apocarotenoids of saffron, accumulate in the flowers of Crocus species in a developmental and tissue-specific manner. In Crocus sieberi, crocins accumulate in stigmas but also in a distinct yellow ... -
Synaptic phosphorylated a-synuclein in dementia with Lewy bodies
(Oxford, 2017-11-23)
Article
Open AccessDementia with Lewy bodies is characterized by the accumulation of Lewy bodies and Lewy neurites in the CNS, both of which are composed mainly of aggregated a-synuclein phosphorylated at Ser129. Although phosphorylated ... -
High-Resolution Morphological Approach to Analyse Elastic Laminae Injuries of the Ascending Aorta in a Murine Model of Marfan Syndrome
(Nature, 2017-05-04)
Article
Open AccessIn Marfan syndrome, the tunica media is disrupted, which leads to the formation of ascending aortic aneurysms. Marfan aortic samples are histologically characterized by the fragmentation of elastic laminae. However, ... -
STED imaging performance estimation by means of Fourier transform analysis
(OSA, 2017-04-17)
Article
Open AccessDue to relatively high powers used in STED, biological samples may be affected by the illumination in the process of image acquisition. Similarly, the performance of the system may be limited by the sample itself. ... -
Polarized cortical tension drives zebrafish epiboly movements
(EMBOpress, 2016-11-09)
Article
Open AccessThe principles underlying the biomechanics of morphogenesis are largely unknown. Epiboly is an essential embryonic event in which three tissues coordinate to direct the expansion of the blastoderm. How and where forces ... -
Two photon versus one photon fluorescence excitation in whispering gallery mode microresonators
(ScienceDirect, 2016-02-01)
Article
Open AccessWe investigate the feasibility of both one photon and two photon fluorescence excitation using whispering gallery mode microresonators. We report the linear and non linear fluorescence real-time detection of labeled IgG ... -
Conformational changes in matrix-isolated 6-methoxyindole: Effects of the thermal and infrared light excitations
(AIP, 2016-03-25)
Article
Open AccessConformational changes induced thermally or upon infrared excitation of matrix-isolated 6-methoxyindole were investigated. Narrowband near-infrared excitation of the first overtone of the N–H stretching vibration of each ...