Early in 2004 the Ministry of Education and Science (Spanish Government), Generalitat de Catalunya (local Catalan Government) and Technical University of Catalonia (UPC) took the initiative of creating a National Supercomputing Center in Barcelona. BSC-CNS (Barcelona Supercomputing Center – Centro Nacional de Supercomputación) is the National Supercomputing Facility in Spain and was officially constituted in April 2005. BSC-CNS manages MareNostrum, one of the most powerful supercomputers in Europe, located at the Torre Girona chapel. The mission of BSC-CNS is to investigate, develop and manage information technology in order to facilitate scientific progress. With this aim, special dedication has been taken to areas such as Computer Sciences, Life Sciences, Earth Sciences and Computational Applications in Science and Engineering.

http://www.bsc.es/

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Recent Submissions

  • A first update on mapping the human genetic architecture of COVID-19 

    COVID-19 Host Genetics Initiative (Nature Research, 2022-08)
    Article
    Open Access
    The COVID-19 pandemic continues to pose a major public health threat, especially in countries with low vaccination rates. To better understand the biological underpinnings of SARS-CoV-2 infection and COVID-19 severity, we ...
  • Identifying cellular cancer mechanisms through pathway-driven data integration 

    Windels, Sam F L; Malod Dognin, Noël; Przulj, Natasa (Oxford University Press, 2022-08-02)
    Article
    Open Access
    Abstract Motivation Cancer is a genetic disease in which accumulated mutations of driver genes induce a functional reorganization of the cell by reprogramming cellular pathways. Current approaches identify cancer pathways ...
  • Overlap of vitamin A and vitamin D target genes with CAKUT-related processes [version 2; peer review: 2 approved, 2 approved with reservations] 

    Ozisik, Ozan; Ehrhart, Friederike; Evelo, Chris T.; Mantovani, Alberto; Baudot, Anaı̈s (F1000Research, 2022)
    Article
    Open Access
    Congenital Anomalies of the Kidney and Urinary Tract (CAKUT) are a group of abnormalities affecting the kidneys and their outflow tracts. CAKUT patients display a large clinical variability as well as a complex aetiology. ...
  • A Hyperactive End to the Atlantic Hurricane Season October–November 2020 

    Klotzbach, Philip J.; Wood, Kimberly M.; Bell, Michael M.; Blake, Eric S.; Bowen, Steven G.; Caron, Louis-Philippe; Collins, Jennifer M.; Gibney, Ethan J.; Schreck III, Carl J.; Truchelut, Ryan E. (American Meteorological Society, 2022)
    Article
    Open Access
    The active 2020 Atlantic hurricane season produced 30 named storms, 14 hurricanes, and 7 major hurricanes (category 3+ on the Saffir–Simpson hurricane wind scale). Though the season was active overall, the final two months ...
  • Climate Services Toolbox (CSTools) v4.0: from climate forecasts to climate forecast information 

    Pérez Zanón, Núria; Caron, Louis-Philippe; Terzago, Silvia; Van Schaeybroeck, Bert; Lledó, Llorenç; Bretonnière, Pierre-Antoine; Delgado Torres, Carlos (Copernicus Publications, 2022)
    Article
    Open Access
    Despite the wealth of existing climate forecast data, only a small part is effectively exploited for sectoral applications. A major cause of this is the lack of integrated tools that allow the translation of data into ...
  • Secondary structure prediction of long noncoding RNA: review and experimental comparison of existing approaches 

    Bugnon, Leandro; Edera, Alejandro A.; Prochetto, Santiago D.; Gerard, Matias; Raad, Jonathan; Chorostecki, Uciel Pablo; Gabaldón, Toni (Oxford University Press, 2022-07)
    Article
    Restricted access - publisher's policy
    MOTIVATION: In contrast to messenger RNAs, the function of the wide range of existing long noncoding RNAs (lncRNAs) largely depends on their structure, which determines interactions with partner molecules. Thus, the ...
  • Metagenomic mining for esterases in the microbial community of Los Rueldos acid mine drainage formation 

    Vidal, Paula; Martínez Martínez, Mónica; Fernandez Lopez, Laura; Roda, Sergi; Méndez García, Celia; Golyshina, Olga V.; Guallar, Victor; Pelaez, Ana Isabel; Ferrer, Manuel (Frontiers Media, 2022-05)
    Article
    Open Access
    Acid mine drainage (AMD) systems are extremely acidic and are metal-rich formations inhabited by relatively low-complexity communities of acidophiles whose enzymes remain mostly uncharacterized. Indeed, enzymes from only ...
  • A multi-pollutant and multi-sectorial approach to screening the consistency of emission inventories 

    Thunis, Philippe; Clappier, Alain; Pisoni, Enrico; Bessagnet, Bertrand; Kuenen, Jeroen; Guevara Vilardell, Marc; Lopez Aparicio, Susana (Copernicus Publications, 2022)
    Article
    Open Access
    Some studies show that significant uncertainties affect emission inventories, which may impeach conclusions based on air-quality model results. These uncertainties result from the need to compile a wide variety of information ...
  • Resolving the fine structure in the energy landscapes of repeat proteins 

    Sanches, Murilo N.; Parra, Rodrigo Gonzalo; Viegas, Rafael Giordano; Oliveira Junior, Antonio Bento; Wolynes, Peter; Ferreiro, Diego U.; Leite, Vitor B.P. (Cambridge University Press, 2022)
    Article
    Open Access
    Ankyrin (ANK) repeat proteins are coded by tandem occurrences of patterns with around 33 amino acids. They often mediate protein–protein interactions in a diversity of biological systems. These proteins have an elongated ...
  • Universal multilayer network exploration by random walk with restart 

    Baptista, Anthony; Gonzalez, Aitor; Baudot, Anaïs (Nature Research, 2022)
    Article
    Open Access
    The amount and variety of data have been increasing drastically for several years. These data are often represented as networks and explored with approaches arising from network theory. Recent years have witnessed the ...
  • The Quest for Orthologs orthology benchmark service in 2022 

    Nevers, Yannis; Jones, Tamsin E M; Jyothi, Dushyanth; Yates, Bethan; Ferret, Meritxell; Portell Silva, Laura; Codo, Laia; Marcet Houben, Marina; Vlasova, Anna; Gabaldon, Toni; Capella Gutierrez, Salvador (Oxford University Press [, 2022)
    Article
    Open Access
    The Orthology Benchmark Service (https://orthology.benchmarkservice.org) is the gold standard for orthology inference evaluation, supported and maintained by the Quest for Orthologs consortium. It is an essential resource ...
  • Towards more effective visualisations in climate services: good practices and recommendations 

    Terrado, Marta; Calvo, Luz; Christel, Isadora (Springer, 2022)
    Article
    Open Access
    Visualisations are often the entry point to information that supports stakeholders’ decision- and policy-making processes. Visual displays can employ either static, dynamic or interactive formats as well as various types ...

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