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dc.contributor.authorGómez Melis, Guadalupe
dc.contributor.otherUniversitat Politècnica de Catalunya. Departament d'Estadística i Investigació Operativa
dc.identifier.citationGómez, G. Some theoretical thoughts when using a composite endpoint to prove the efficacy of a treatment. A: International Workshop on Statistical Modelling. "Proceedings of the 26th International Workshop on Statistical Modelling". València: 2011, p. 14-21.
dc.description.abstractThis paper discusses, following Gómez and Lagakos (2011) methodology, to what extent is there a gain in efficiency from adding a component event to a relevant endpoint when the treatment effect on this component is not as strong as on the original relevant endpoint under ideal (independence) circumstances. It presents the bivariate copula model used to overcome the independence assumption and presents the relationship between the components of the asymptotic relative efficiency and a set of interpretable parametres.
dc.format.extent8 p.
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Spain
dc.subjectÀrees temàtiques de la UPC::Matemàtiques i estadística::Estadística matemàtica
dc.subject.otherAsymptotic Relative E_ciency
dc.subject.otherComposite Endpoints
dc.subject.otherComposite Outcomes
dc.subject.otherCopula Model
dc.subject.otherLogrank tests AMS 62N
dc.titleSome theoretical thoughts when using a composite endpoint to prove the efficacy of a treatment
dc.typeConference report
dc.contributor.groupUniversitat Politècnica de Catalunya. GREMA - Grup de Recerca en Estadística Matemàtica i les seves Aplicacions
dc.description.peerreviewedPeer Reviewed
dc.subject.amsClassificació AMS::62 Statistics::62N Survival analysis and censored data
dc.rights.accessOpen Access
dc.description.versionPostprint (published version)
local.citation.authorGómez, G.
local.citation.contributorInternational Workshop on Statistical Modelling
local.citation.publicationNameProceedings of the 26th International Workshop on Statistical Modelling

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