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dc.contributor.authorGil Mur, Francisco Javier
dc.contributor.authorManzanares, Norberto
dc.contributor.authorBadet de Mena, Armando
dc.contributor.authorAparicio Bádenas, Conrado José
dc.contributor.authorGinebra Molins, Maria Pau
dc.contributor.otherUniversitat Politècnica de Catalunya. Departament de Ciència dels Materials i Enginyeria Metal·lúrgica
dc.identifier.citationGil, F.J. [et al.]. Biomimetic treatment on dental implants for short-term bone regeneration. "Clinical oral investigations", 01 Gener 2014, vol. 18, núm. 1, p. 59-66.
dc.description.abstractObjectives The main purpose of this work was to assess the short-term bone regenerative potential of new osteoconductive implants. The novelty of the study lies in the analysis of the effectiveness of a novel two-step treatment which combines shot-blasting with a thermo-chemical treatment, at very short times after implant placement in a minipig model. Materials and methods Three hundred twenty implants with four different surface treatments, namely bioactivated sur- faces, micro-rough grit-blasted, micro-rough acid-etched and smooth as-machined titanium implants were placed into the bone of 20 minipigs. The percent of bone-to-implant contact was determined 3 days, 1, 2, 3 and 10 weeks after implant placement by histomorphometric analysis. Surface composition, topography and wettability of the implant specimens were analysed. Results The combination of shot-blasting and thermo- chemical treatment accelerated bone regeneration at early stages in comparison with all other treatments between day 3 and week 3 ( p <0.05). The value of osseointegration attained at week 2 was maintained until the end of the experiment without any significant changes (percent direct contact ≈ 85 %). This was mostly attributed to the ability of these implants to form in vivo a layer of apatitic mineral that coated the implant and could rapidly stimu- late bone nucleation and growth from the implant surface. Conclusions The surface quality resulting from this treat- ment on cpTi provided dental implants with a unique ability of rapid bone regeneration and osseointegration. Clinical relevance This treatment represents a step forward in the direction of reducing the time prior to implant loading
dc.format.extent8 p.
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Spain
dc.subjectÀrees temàtiques de la UPC::Enginyeria dels materials
dc.subject.lcshDental implants
dc.subject.otherTitanium implants
dc.titleBiomimetic treatment on dental implants for short-term bone regeneration
dc.subject.lemacImplants dentals
dc.contributor.groupUniversitat Politècnica de Catalunya. BBT - Biomaterials, Biomecànica i Enginyeria de Teixits
dc.description.peerreviewedPeer Reviewed
dc.rights.accessRestricted access - publisher's policy
dc.description.versionPostprint (published version)
dc.contributor.covenanteeUniversity of Minnesota School of Dentistry
upcommons.citation.authorGil, F.J.; Manzanares, N.; Badet, A.; Aparicio, C.; Ginebra, M.P.
upcommons.citation.publicationNameClinical oral investigations

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