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dc.contributor.authorMestres Beà, Gemma
dc.contributor.authorAbdolhosseini, Masha
dc.contributor.authorBowles, Walter
dc.contributor.authorHuang, S.H.
dc.contributor.authorAparicio Bádenas, Conrado José
dc.contributor.authorGorr, Sven Ulrik
dc.contributor.authorGinebra Molins, Maria Pau
dc.contributor.otherUniversitat Politècnica de Catalunya. Departament de Ciència dels Materials i Enginyeria Metal·lúrgica
dc.date.accessioned2013-11-18T10:04:35Z
dc.date.created2013-09
dc.date.issued2013-09
dc.identifier.citationMestres, G. [et al.]. Antimicrobial properties and dentin bonding strength of magnesium phosphate cements. "Acta biomaterialia", Setembre 2013, vol. 9, núm. 9, p. 8384-8393.
dc.identifier.issn1742-7061
dc.identifier.urihttp://hdl.handle.net/2117/20634
dc.description.abstractThe main objective of this work was to assess the antimicrobial properties and the dentin-bonding strength of novel magnesium phosphate cements (MPC). Three formulations of MPC, consisting of magnesium oxide and a phosphate salt, NH4H2PO4, NaH2PO4 or a mixture of both, were evaluated. As a result of the setting reaction, MPC transformed into either struvite (MgNH4PO4·6H2O) when NH4H2PO4 was used or an amorphous magnesium sodium phosphate when NaH2PO4 was used. The MPC had appropriate setting times for hard tissue applications, high early compressive strengths and higher strength of bonding to dentin than commercial mineral trioxide aggregate cement. Bacteriological studies were performed with fresh and aged cements against three bacterial strains, Escherichia coli, Pseudomonas aeruginosa (planktonic and in biofilm) and Aggregatibacter actinomycetemcomitans. These bacteria have been associated with infected implants, as well as other frequent hard tissue related infections. Extracts of different compositions of MPC had bactericidal or bacteriostatic properties against the three bacterial strains tested. This was associated mainly with a synergistic effect between the high osmolarity and alkaline pH of the MPC. These intrinsic antimicrobial properties make MPC preferential candidates for applications in dentistry, such as root fillers, pulp capping agents and cavity liners.
dc.format.extent10 p.
dc.language.isoeng
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Spain
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
dc.subjectÀrees temàtiques de la UPC::Enginyeria dels materials
dc.subject.lcshMagnesium phosphate
dc.subject.lcshBiomedical materials
dc.subject.lcshBone cements
dc.subject.otherAntibacterial properties
dc.subject.otherBonding strength
dc.subject.otherDental cement
dc.subject.otherMagnesium phosphate cement
dc.subject.otherStruvite
dc.titleAntimicrobial properties and dentin bonding strength of magnesium phosphate cements
dc.typeArticle
dc.subject.lemacCiments ossis
dc.subject.lemacBiomaterials
dc.subject.lemacFosfat de magnesi
dc.contributor.groupUniversitat Politècnica de Catalunya. BBT - Biomaterials, Biomecànica i Enginyeria de Teixits
dc.identifier.doi10.1016/j.actbio.2013.05.032
dc.description.peerreviewedPeer Reviewed
dc.rights.accessRestricted access - publisher's policy
local.identifier.drac12773535
dc.description.versionPostprint (published version)
dc.date.lift10000-01-01
dc.contributor.covenanteeUniversity of Minnesota School of Dentistry
local.citation.authorMestres, G.; Abdolhosseini, M.; Bowles, W.; Huang, S.H.; Aparicio, C.; Gorr, S-U.; Ginebra, M.P.
local.citation.publicationNameActa biomaterialia
local.citation.volume9
local.citation.number9
local.citation.startingPage8384
local.citation.endingPage8393


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