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dc.contributor.authorRincón Fontán, Myriam
dc.contributor.authorRodríguez López, Lorena
dc.contributor.authorVecino Bello, Xanel
dc.contributor.authorCruz Freire, José Manuel
dc.contributor.authorMoldes Menduíña, Ana Belén
dc.contributor.otherUniversitat Politècnica de Catalunya. Departament d'Enginyeria Química
dc.date.accessioned2020-07-14T13:25:46Z
dc.date.issued2020-06-01
dc.identifier.citationRincón, M. [et al.]. Potential application of a multifunctional biosurfactant extract obtained from corn as stabilizing agent of vitamin C in cosmetic formulations. "Sustainable Chemistry and Pharmacy", 1 Juny 2020, vol. 16, p. 100248:1-100248:7.
dc.identifier.issn2352-5541
dc.identifier.urihttp://hdl.handle.net/2117/192940
dc.description.abstractVitamin C is an essential nutrient for human health, which can be found in the epidermis, playing an important role in the collagen production and protection of the skin. However, humans cannot produce this vitamin, being necessary to include it in health care products. Moreover, vitamin C is easily degradable making quite difficult to keep it as L-ascorbic acid form during long time. Thus, cosmetic and pharmaceutical industries include dehydrated vitamin C in its formulations to prevent its degradation. Therefore, it must be rehydrated before use, leading to a tedious process. The aim of this work was to study the addition of a multifunctional biosurfactant extract (BS), obtained from corn wet-milling industry, to an aqueous solution of L-ascorbic acid (AA) in order to improve the stability of this vitamin. A Box-Behnken factorial design was established in order to predict the degradation of vitamin C, using as independent variables: the concentration of vitamin C, the concentration of BS and the storage time. This study allowed to obtain a theoretical equation that predicts the degradation of vitamin C in presence and absence of BS, which was quantified by high performance liquid chromatography (HPLC). The experimental results showed that the presence of BS can inhibit the degradation of vitamin C in water up to 58% after 14 days in comparison with the same assays in absence of biosurfactant. This work opens the door to the use of this BS as stabilizing agent of formulations containing unstable active principles like vitamin C.
dc.language.isoeng
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Spain
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
dc.subjectÀrees temàtiques de la UPC::Enginyeria química::Biotecnologia
dc.subject.otherL-ascorbic acid
dc.subject.otherBiosurfactant extract
dc.subject.otherCorn stream
dc.subject.otherAntioxidant
dc.subject.otherStatistics
dc.titlePotential application of a multifunctional biosurfactant extract obtained from corn as stabilizing agent of vitamin C in cosmetic formulations
dc.typeArticle
dc.subject.lemacCosmètics
dc.subject.lemacAntioxidants
dc.contributor.groupUniversitat Politècnica de Catalunya. R2EM - Resource Recovery and Environmental Management
dc.identifier.doi10.1016/j.scp.2020.100248
dc.description.peerreviewedPeer Reviewed
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/abs/pii/S2352554119302633
dc.rights.accessRestricted access - publisher's policy
local.identifier.drac28130812
dc.description.versionPostprint (author's final draft)
dc.date.lift2022-06-30
local.citation.authorRincón, M.; Rodríguez, L.; Vecino, X.; Cruz, J.; Moldes, A.
local.citation.publicationNameSustainable Chemistry and Pharmacy
local.citation.volume16
local.citation.startingPage100248:1
local.citation.endingPage100248:7


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Attribution-NonCommercial-NoDerivs 3.0 Spain
Except where otherwise noted, content on this work is licensed under a Creative Commons license : Attribution-NonCommercial-NoDerivs 3.0 Spain